Juan Rodriguez-Vita
@jrodriguezvita.bsky.social
Group leader at CIPF in Valencia, Spain, investigating tumor-stroma communication. My own views. He/him/his. https://www.cipf.es/science/research/cancer/tumor-stroma-communication
Que la financiación en ciencia es insuficiente no solo los pensamos en @aseica.bsky.social, sino que es una impresión compartida por el 80% de la población. Es hora de que la política escuche a la sociedad. #SinCienciaNoHayFuturo
July 30, 2025 at 2:40 PM
Que la financiación en ciencia es insuficiente no solo los pensamos en @aseica.bsky.social, sino que es una impresión compartida por el 80% de la población. Es hora de que la política escuche a la sociedad. #SinCienciaNoHayFuturo
Confieso que esto me ha hecho reír más de lo que habría sido normal.
July 10, 2025 at 8:00 AM
Confieso que esto me ha hecho reír más de lo que habría sido normal.
"A partir de mañana podrá consultar en Facilit@, su Carpeta Virtual de Expedientes"
June 17, 2025 at 6:19 AM
"A partir de mañana podrá consultar en Facilit@, su Carpeta Virtual de Expedientes"
Domingo=arroz con cosas
March 9, 2025 at 2:10 PM
Domingo=arroz con cosas
Powerful video showing the contribution that immigrants provide to the countries where they live. As a former immigrant in Germany myself, I feel very touched by it.
February 27, 2025 at 10:39 AM
Powerful video showing the contribution that immigrants provide to the countries where they live. As a former immigrant in Germany myself, I feel very touched by it.
You're finally resting again. We'll miss you so much, you were a great companion.
February 22, 2025 at 12:05 PM
You're finally resting again. We'll miss you so much, you were a great companion.
Se va acercando la Trobada de Alcoi. Este año centrada en el cáncer y el estilo de vida. La inscripción es gratuita y hay premios a las mejores presentaciones. Más información en este link: www.trailsolidarialcoi.org/inici-trobad...
February 17, 2025 at 12:28 PM
Se va acercando la Trobada de Alcoi. Este año centrada en el cáncer y el estilo de vida. La inscripción es gratuita y hay premios a las mejores presentaciones. Más información en este link: www.trailsolidarialcoi.org/inici-trobad...
"We followed your protocol, but we adapted some steps"
January 31, 2025 at 5:11 PM
"We followed your protocol, but we adapted some steps"
¡Yippie ki-yay, HdP!
January 12, 2025 at 10:00 PM
¡Yippie ki-yay, HdP!
Did I close the -80?
November 22, 2024 at 8:51 PM
Did I close the -80?
The abstract vs. the paper
November 21, 2024 at 11:37 AM
The abstract vs. the paper
That author in your paper:
November 20, 2024 at 9:09 AM
That author in your paper:
CRISPR is amazing
November 19, 2024 at 8:17 AM
CRISPR is amazing
"How did you end up working in Accademia?"
November 18, 2024 at 6:21 PM
"How did you end up working in Accademia?"
English speakers in academia
November 17, 2024 at 10:19 AM
English speakers in academia
Finally, when we blocked retinoic acid signaling during pre-cachexia, we were able to revert EC-Notch1-promoted WAT remodeling. This suggests that angiocrine signaling is a key player in cachexia development. 6/6
November 16, 2024 at 2:39 PM
Finally, when we blocked retinoic acid signaling during pre-cachexia, we were able to revert EC-Notch1-promoted WAT remodeling. This suggests that angiocrine signaling is a key player in cachexia development. 6/6
We observed that retinoic acid induced a hypermetabolic state as well as unresolved inflammation which contributes to fibrosis development. 5/6
November 16, 2024 at 2:39 PM
We observed that retinoic acid induced a hypermetabolic state as well as unresolved inflammation which contributes to fibrosis development. 5/6
We observed that Notch1 activation in ECs led to WAT wasting in the absence of tumor cells (genetic mouse model). We started a thorough search for the mechanism and found that Notch1 increases retinoic acid production directly and indirectly via angiocrine signaling.
November 16, 2024 at 2:39 PM
We observed that Notch1 activation in ECs led to WAT wasting in the absence of tumor cells (genetic mouse model). We started a thorough search for the mechanism and found that Notch1 increases retinoic acid production directly and indirectly via angiocrine signaling.
Then, we confirmed that also cachectic patients showed active Notch signaling in WAT. 3/6
November 16, 2024 at 2:39 PM
Then, we confirmed that also cachectic patients showed active Notch signaling in WAT. 3/6
We hypothesized that if Notch1 is active in the endothelium to promote metastasis (linkinghub.elsevier.com/retrieve/pii/S…), it could also have a cancer-promoting role in other distant organs. We evaluated WAT ECs during cachexia development and observed increased Notch1 activity. 2/6
November 16, 2024 at 2:39 PM
We hypothesized that if Notch1 is active in the endothelium to promote metastasis (linkinghub.elsevier.com/retrieve/pii/S…), it could also have a cancer-promoting role in other distant organs. We evaluated WAT ECs during cachexia development and observed increased Notch1 activity. 2/6
Let me tell you about the work that we published last year in Nature Cancer (@natureportfolio.bsky.social). It was a tremendous effort from Jacquelin Taylor within Andreas Fischer's lab. In it, we describe a new role of endothelial cells to promote cancer cachexia: nature.com/articles/s4301… 1/6
November 16, 2024 at 2:39 PM
Let me tell you about the work that we published last year in Nature Cancer (@natureportfolio.bsky.social). It was a tremendous effort from Jacquelin Taylor within Andreas Fischer's lab. In it, we describe a new role of endothelial cells to promote cancer cachexia: nature.com/articles/s4301… 1/6
The PI when two students are discussing cool results
November 16, 2024 at 7:10 AM
The PI when two students are discussing cool results
Watching Stardust again and realizing that it has Daredevil and Superman in it!
August 25, 2023 at 3:05 PM
Watching Stardust again and realizing that it has Daredevil and Superman in it!