An idea we started in 2019 is now published in @natneuro.nature.com! Excited to share our new study: rdcu.be/eRvdA

Congrats to Mengmeng Jin and our team! Heartfelt thanks to all collaborators for their support, and to the reviewers for their insightful comments!

This review was actually written once before (the section on methodological considerations for creating chimeric models is shown in the image below), but it didn’t make it to publication at the time.

I was inspired by Dr. Suchun Zhang’s work on differentiating human PSCs + transplanting them into mice, and Dr. Steven Goldman’s work on human oligodendroglia taking over mouse brains.

We discussed the idea of chimeric models in our 2014 Nat Commun paper 👇

Thrilled to share our review just published in @cp-neuron.bsky.social ! 🎉
Big shoutout to Ava, Mengmeng, and our entire team!
authors.elsevier.com/a/1k-uh3BtfH...