Jeroen Guikema
@jeroenguikema.bsky.social
Molecular biologist. 🧬Principal investigator at University of Amsterdam 🇳🇱 Research interests: immune repertoire diversification mechanisms, oncogenic signaling, B-cells, multiple myeloma #medsky #scisky #academicsky #biosky
Reposted by Jeroen Guikema
Scientists themselves determine what is valued within science. Yet we act as if beholden to external managers, bean-counters who confuse the production of papers with scientific progress.
We don't have to find better ways to navigate the prison of metrics-driven scientific assessment.
We don't have to find better ways to navigate the prison of metrics-driven scientific assessment.
October 25, 2025 at 9:35 PM
Scientists themselves determine what is valued within science. Yet we act as if beholden to external managers, bean-counters who confuse the production of papers with scientific progress.
We don't have to find better ways to navigate the prison of metrics-driven scientific assessment.
We don't have to find better ways to navigate the prison of metrics-driven scientific assessment.
This aligns with findings from our lab where we show that AKT inhibition synergizes with MCL-1 inhibition to induce cell death in myeloma cells. ashpublications.org/bloodadvance...
AKT signaling restrains tumor suppressive functions of FOXO transcription factors and GSK3 kinase in multiple myeloma
Key Points. FOXO transcription factors and the GSK3 kinase are pivotal tumor suppressors restrained by AKT activity in MM cells.FOXO and GSK3 destabilize M
ashpublications.org
May 4, 2025 at 9:20 AM
This aligns with findings from our lab where we show that AKT inhibition synergizes with MCL-1 inhibition to induce cell death in myeloma cells. ashpublications.org/bloodadvance...
Reposted by Jeroen Guikema
This is what we know about the so-called 'epithelial-mesenchymal transition'
'Lack of basic rationale in epithelial-mesenchymal transition and its related concepts'
cellandbioscience.biomedcentral.com/articles/10....
'Lack of basic rationale in epithelial-mesenchymal transition and its related concepts'
cellandbioscience.biomedcentral.com/articles/10....
May 3, 2025 at 11:26 AM
This is what we know about the so-called 'epithelial-mesenchymal transition'
'Lack of basic rationale in epithelial-mesenchymal transition and its related concepts'
cellandbioscience.biomedcentral.com/articles/10....
'Lack of basic rationale in epithelial-mesenchymal transition and its related concepts'
cellandbioscience.biomedcentral.com/articles/10....