Joao Pereira
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jdpereira.bsky.social
Joao Pereira
@jdpereira.bsky.social
Neuroscientist.
Assistant Professor of Neurology at UAB

Trying for a better, more humane approach to science.

Interested in neurodegenerative diseases, AI toolsets, and science in general!

STOP ALS.
Pinned
“But when I see something
I’ll reach and grab some wings
And fly away
During the day

Why can’t people do the same as birds?
I’ll say it with other words:
Why am I heavy and not light?
And why can’t I see it too?
A perfect bird’s eye view
When the sun is shining bright.”

7yo.

(Now 8yo)
“The graveyard is filled with important men
Could not be spared but were in the end.”

The Trans-Siberian Orchestra did not have to go this hard, but I am so glad they did.
a woman is playing a piano on a stage while flames are coming out of the keyboard .
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November 21, 2025 at 1:03 PM
It’s not a “claim”!!

The “claim” is that they do!!

Otherwise everything works - vaccines also haven’t been ruled out to cause people to turn into Mickey freaking Mouse!!
This is completely disgusting. Today, the CDC updated their vaccine safety page. It now says:

“The claim "vaccines do not cause autism" is not an evidence-based claim because studies have not ruled out the possibility that infant vaccines cause autism”.
November 20, 2025 at 12:52 PM
“I think I’m a poet.”
9yo
a close up of a man 's face with the words " i know " on his chest
ALT: a close up of a man 's face with the words " i know " on his chest
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November 20, 2025 at 9:30 AM
“Patience is the key to life, but it won’t unlock your heart. Only the people you loved, and love you back, your family and friends can do that.

At the end of your life, only love will unlock your heart.”

9yo channeling…. Something.
a man in a black shirt is making a funny face while sitting at a table .
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November 20, 2025 at 1:26 AM
One of the babies has been sleeping for four hours.

We’re in for a wild night.
a man with a beard says prepare for glory
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November 19, 2025 at 11:40 PM
Ok, so a total of 57km in the last four days. Funny how it was fine yesterday and today…

It’s not fine.

It’s not even remotely close to fine.
a woman in a suit says everything hurts and i 'm dying .
ALT: a woman in a suit says everything hurts and i 'm dying .
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November 19, 2025 at 8:45 PM
A restaurant was just raided close to us.

I’d never been, but there is such a strange feeling of loss.

Like the loss of safety, of sanctuary.

Restaurants felt like a safe place.

I like to think even the Kurgan would behave.
a man in a leather jacket is standing in a church with a priest .
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November 19, 2025 at 6:42 PM
I find it hilarious the crowd of “Harvard has moneys!!”

And what? They should distribute it for the good of the people?

Ya can’t advocate that AND capitalism mate.
You Need To Be Consistent Get It Together GIF
ALT: You Need To Be Consistent Get It Together GIF
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November 19, 2025 at 2:24 AM
A while back 9yo made a story about a new holiday everyone could celebrate: a birthday for those who did not know their birthday.

She set a date: it’s today.

So, I drove to the store, and we picked up a cake, and we had a birthday for those that don’t.

Happy birthday everyone.
a birthday cake with lit candles and the words happy birthday on it
ALT: a birthday cake with lit candles and the words happy birthday on it
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November 17, 2025 at 9:17 PM
Did 17.2.

I’ll get there.
The thing I miss the most about Boston was walking around everywhere. Can’t walk around nearly as much here, and it’s taking a toll.

So this weekend I’m on track to walk 20 miles, and hope to keep that up during the week.
a cartoon of spongebob saying delulu with his hands
ALT: a cartoon of spongebob saying delulu with his hands
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November 17, 2025 at 1:25 AM
The thing I miss the most about Boston was walking around everywhere. Can’t walk around nearly as much here, and it’s taking a toll.

So this weekend I’m on track to walk 20 miles, and hope to keep that up during the week.
a cartoon of spongebob saying delulu with his hands
ALT: a cartoon of spongebob saying delulu with his hands
media.tenor.com
November 16, 2025 at 6:00 PM
Hey mushroom people (Eheh) what is this?
November 15, 2025 at 9:16 PM
If you’re there go check this out!!

So proud to have Anna and Gessica representing the lab!
So excited for upcoming #SfN25 🧠! I will be giving a talk during a nanosymposium all about using iPSC-derived models for studying neuronal function! Please stop by and check all the amazing talks for this session!
@sfn.org
November 15, 2025 at 7:16 PM
Sigh.

It’s actually faster for me to run RNASeq analysis on my MacBook than to read all the Uni’s cluster documentation.

All these tiny, huge barriers to entry on everything.
elmo from sesame street sitting at a table with a purple cup and straw
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November 15, 2025 at 2:41 PM
Hey, any #ALS researchers want to get together for a basic biology consortium (TALS has open proposals)?

DM me if so - happy to do a bunch of cool stuff in our organoids!
a close up of a feather on a rock with the words `` hello '' written in white letters .
ALT: a close up of a feather on a rock with the words `` hello '' written in white letters .
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November 15, 2025 at 2:33 PM
Oh we got a Guide TOC update!!

(Reads).
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ALT: homer simpson from the simpsons is standing in front of a shelf with stuffed animals and says d ' oh .
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November 14, 2025 at 10:31 PM
‼️ Hi everyone,

I usually don’t pull out the “I’m a microbiologist” card often but my local store was selling these at a discount.

Best before 2024.
In some cases that may not be an issue, but these smelled foul. Not just fermentation, bad bad.
Nothing usually wrong with the product but watch out.
November 14, 2025 at 3:03 PM
Help:

We have developed an organoid model of diabetic neuropathy.

It has oligodendrocytes, myelin, and adding diabetic stimuli makes them lose myelination, and break down mitochondria.

Further yet, we show this can be prevented with pharmacological intervention.

Which foundations may like this?
a fluffy cat is sitting on a wooden table with the words `` help '' written on it .
ALT: a fluffy cat is sitting on a wooden table with the words `` help '' written on it .
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November 13, 2025 at 5:22 PM
“Dad I’m afraid people won’t like us and want us to leave.”

My US Citizen 7yo daughter just casually breaking my heart.

(She is adorable, no one could ever dislike her. Me on the other hand…)
marie from the aristocats is looking out of a window with her paws crossed .
ALT: marie from the aristocats is looking out of a window with her paws crossed .
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November 13, 2025 at 5:20 PM
The twins can now play hungry hungry hippos.

That is all.
a group of stuffed animals are sitting on top of a red table .
ALT: a group of stuffed animals are sitting on top of a red table .
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November 13, 2025 at 2:53 AM
Asked separately: So, if I was an instrument, what would I be?

9yo: A drum!! You’re exciting!

7yo: A piano. You calm me.

Wow.

What about mom?

9yo: A piano. She soothes me.

7yo: A clarinet! She loves to sing!

How we all sound different to different people.

(Unanimous:the twins are maracas)
a man wearing a sombrero and a red poncho is holding maracas .
ALT: a man wearing a sombrero and a red poncho is holding maracas .
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November 12, 2025 at 2:00 PM
Reposted by Joao Pereira
Dozens of women converged on Cape Cod toward the end of summer for a unique annual gathering of a club no one really wanted to be a member of: women diagnosed in their 20s and early 30s with amyotrophic lateral sclerosis, or ALS.
The Young Women Grappling With an ‘Old Man’s Disease’
Diagnosed with A.L.S., they traded stories, drank tequila and made grim jokes at a unique annual gathering on Cape Cod.
nyti.ms
November 12, 2025 at 1:20 AM
“Hey girls, I used to read these when I was a kid!

Your uncle and aunt gave you this one, I haven’t read it yet, and.. cellphones??? There’s cellphones?

Wait it’s book 66??”

Me, stunned there is a Portuguese famous five type of book series that has over 66 books and started in 1982.
a man in a suit and tie talks to a woman with the words now i feel old behind him
ALT: a man in a suit and tie talks to a woman with the words now i feel old behind him
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November 12, 2025 at 1:19 AM
Just had a deep conversation about good and evil with the girls that culminated in the Manhattan project (with as little detail as possible).

And before you say anything: they asked, and I don’t lie.

Sigh.

We teach them good and evil with such clarity that every single shade of gray hurts.
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ALT: a pixel art illustration of a full moon rising over a lake with trees in the foreground .
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November 11, 2025 at 11:52 PM