Jürg Bähler
@jbahler.bsky.social
Geneticist, Professor at UCL, Secondment at Francis Crick Institute.
fission yeast | turquoise killifish | cellular quiescence | aging | functions of understudied genes and non-coding RNAs
fission yeast | turquoise killifish | cellular quiescence | aging | functions of understudied genes and non-coding RNAs
Reposted by Jürg Bähler
www.embopress.org/doi/full/10....
Here's an important and topical perspective from Nektarios Tavernarakis. Wise words!
Here's an important and topical perspective from Nektarios Tavernarakis. Wise words!
For the love of frontier research, or why Elon’s rockets keep blowing up | EMBO reports
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
www.embopress.org
October 25, 2025 at 4:48 PM
www.embopress.org/doi/full/10....
Here's an important and topical perspective from Nektarios Tavernarakis. Wise words!
Here's an important and topical perspective from Nektarios Tavernarakis. Wise words!
Reposted by Jürg Bähler
PomBase introduces two new interactive views for GO-CAM pathway models: Summary Maps (high-level, visual overview) and Mega-Models (connected models). Check them out here: lnkd.in/gfxNRdua
July 31, 2025 at 9:07 AM
PomBase introduces two new interactive views for GO-CAM pathway models: Summary Maps (high-level, visual overview) and Mega-Models (connected models). Check them out here: lnkd.in/gfxNRdua
Reposted by Jürg Bähler
Well this is interesting: Psilocybin treatment extends cellular lifespan and improves survival of aged mice
Guess all of us older adults need to stock up on mushrooms!!!
www.nature.com/articles/s41...
Guess all of us older adults need to stock up on mushrooms!!!
www.nature.com/articles/s41...
Psilocybin treatment extends cellular lifespan and improves survival of aged mice - npj Aging
npj Aging - Psilocybin treatment extends cellular lifespan and improves survival of aged mice
www.nature.com
July 31, 2025 at 12:40 PM
Well this is interesting: Psilocybin treatment extends cellular lifespan and improves survival of aged mice
Guess all of us older adults need to stock up on mushrooms!!!
www.nature.com/articles/s41...
Guess all of us older adults need to stock up on mushrooms!!!
www.nature.com/articles/s41...
Reposted by Jürg Bähler
Superhappy to share the last paper from my PhD in @litinice.bsky.social lab. We evolved yeasts with humanized telomeric repeats and discovered that they adapt through amplification of telomere-binding proteins and inactivation of the DNA damage response.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
The adaptive molecular landscape of reprogrammed telomeric sequences
Telomeric sequences vary across the tree of life and intimately co-evolve with telomere-binding protein complexes. However, the molecular mechanisms allowing organisms to adapt to new telomeric sequen...
www.biorxiv.org
July 3, 2025 at 8:29 AM
Superhappy to share the last paper from my PhD in @litinice.bsky.social lab. We evolved yeasts with humanized telomeric repeats and discovered that they adapt through amplification of telomere-binding proteins and inactivation of the DNA damage response.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
After 25 years, it was wonderful to reunite with all members of our original research group!
June 13, 2025 at 4:58 PM
After 25 years, it was wonderful to reunite with all members of our original research group!
Reposted by Jürg Bähler
FlyBase needs your help!
Because of recent changes to government funding, the NIH grant that supported FlyBase has been "terminated." flybase.org
Because of recent changes to government funding, the NIH grant that supported FlyBase has been "terminated." flybase.org
June 9, 2025 at 2:42 PM
FlyBase needs your help!
Because of recent changes to government funding, the NIH grant that supported FlyBase has been "terminated." flybase.org
Because of recent changes to government funding, the NIH grant that supported FlyBase has been "terminated." flybase.org
Reposted by Jürg Bähler
We are excited to be recruiting 3 post-doctoral researchers to study glial cell dysfunction in #agingresearch and #neurodegeneration, including one position using #Drosophila models! If you are interested, please read more below to get in touch or apply (links in thread).
June 1, 2025 at 3:26 PM
We are excited to be recruiting 3 post-doctoral researchers to study glial cell dysfunction in #agingresearch and #neurodegeneration, including one position using #Drosophila models! If you are interested, please read more below to get in touch or apply (links in thread).
Reposted by Jürg Bähler
We found a new way to make mice live 30% longer! 🧪 #aging #longevity #rapamycin
A combination of classic longevity drug rapamycin with cancer drug trametinib was more effective than either on its own.
Read more about the exciting results here:
A combination of classic longevity drug rapamycin with cancer drug trametinib was more effective than either on its own.
Read more about the exciting results here:
New drug cocktail makes mice live 30% longer – Andrew Steele
Rapamycin + anti-cancer drug trametinib does better than rapa on its own!
andrewsteele.co.uk
May 31, 2025 at 3:27 PM
We found a new way to make mice live 30% longer! 🧪 #aging #longevity #rapamycin
A combination of classic longevity drug rapamycin with cancer drug trametinib was more effective than either on its own.
Read more about the exciting results here:
A combination of classic longevity drug rapamycin with cancer drug trametinib was more effective than either on its own.
Read more about the exciting results here:
Reposted by Jürg Bähler
We will put forward a 500 million package for 2025-2027 to make Europe a magnet for researchers.
As well as ambitious proposals for R&I in the next EU budget.
We will also offer the best and brightest the right incentives to come to Europe ↓
As well as ambitious proposals for R&I in the next EU budget.
We will also offer the best and brightest the right incentives to come to Europe ↓
May 5, 2025 at 10:02 AM
We will put forward a 500 million package for 2025-2027 to make Europe a magnet for researchers.
As well as ambitious proposals for R&I in the next EU budget.
We will also offer the best and brightest the right incentives to come to Europe ↓
As well as ambitious proposals for R&I in the next EU budget.
We will also offer the best and brightest the right incentives to come to Europe ↓
Reposted by Jürg Bähler
The Economist cover 👀
April 24, 2025 at 4:38 PM
The Economist cover 👀
Reposted by Jürg Bähler
A periodic reminder to cite your resources. Although no @pombase.bsky.social update in this issue, we did sneak onto the cover illustration.
This issue of #GENETICS offers updates on 6 model organism databases & knowledgebases: buff.ly/Mn0hIzl
🔎 AgBioData Consortium
🔎 Candida Genome Database
🔎 Saccharomyces Genome Database
🔎 SpudDB
🔎 Unified Phenotype Ontology
🔎 Zebrafish Information Network
Remember to cite your community resources!
🔎 AgBioData Consortium
🔎 Candida Genome Database
🔎 Saccharomyces Genome Database
🔎 SpudDB
🔎 Unified Phenotype Ontology
🔎 Zebrafish Information Network
Remember to cite your community resources!
April 9, 2025 at 5:19 AM
A periodic reminder to cite your resources. Although no @pombase.bsky.social update in this issue, we did sneak onto the cover illustration.
Reposted by Jürg Bähler
I spent a very nice couple of days at the "Hidden Cell, Dark Genome" conference in Edinburgh last week ... and even got to win a supercute eukaryotic cell 🙂 Thanks to the organisers for arranging the meeting!
April 9, 2025 at 6:39 AM
I spent a very nice couple of days at the "Hidden Cell, Dark Genome" conference in Edinburgh last week ... and even got to win a supercute eukaryotic cell 🙂 Thanks to the organisers for arranging the meeting!
Reposted by Jürg Bähler
You can now ✅ verify your #OpenCloning sequences using sequencing data 🧬 (Sanger or Nanopore). Just load your files 📂 and see where they align! 🎯
#OpenCloning is free & Open Source, and supports most cloning methods! 🔬🛠️
👉 Try it here: opencloning.org
🎞️ Demo video: youtu.be/n0hedzvpW88?...
#OpenCloning is free & Open Source, and supports most cloning methods! 🔬🛠️
👉 Try it here: opencloning.org
🎞️ Demo video: youtu.be/n0hedzvpW88?...
April 1, 2025 at 1:53 PM
You can now ✅ verify your #OpenCloning sequences using sequencing data 🧬 (Sanger or Nanopore). Just load your files 📂 and see where they align! 🎯
#OpenCloning is free & Open Source, and supports most cloning methods! 🔬🛠️
👉 Try it here: opencloning.org
🎞️ Demo video: youtu.be/n0hedzvpW88?...
#OpenCloning is free & Open Source, and supports most cloning methods! 🔬🛠️
👉 Try it here: opencloning.org
🎞️ Demo video: youtu.be/n0hedzvpW88?...
Reposted by Jürg Bähler
Together with fellow @biologists.bsky.social EiCs we've written about the unprecedented cuts & policy changes to research in the US
We stand with our US colleagues during this challenging time
Science transcends borders—setbacks in one nation affect us all
journals.biologists.com/dev/article/...
We stand with our US colleagues during this challenging time
Science transcends borders—setbacks in one nation affect us all
journals.biologists.com/dev/article/...
Science under siege: protecting scientific progress in turbulent times
As Editors-in-Chief of The Company of Biologists' journals, we have been watching with growing concern the policy changes in the United States of America (USA) and the challenges that these are creati...
journals.biologists.com
March 13, 2025 at 9:13 PM
Together with fellow @biologists.bsky.social EiCs we've written about the unprecedented cuts & policy changes to research in the US
We stand with our US colleagues during this challenging time
Science transcends borders—setbacks in one nation affect us all
journals.biologists.com/dev/article/...
We stand with our US colleagues during this challenging time
Science transcends borders—setbacks in one nation affect us all
journals.biologists.com/dev/article/...
Reposted by Jürg Bähler
It's time for individuals and organizations in Europe and other democratic countries to move mission- or life-critical IT services and infrastructure outside the reach of the US government; noting that US tech companies have already largely subordinated themselves.
www.huber.embl.de/group/posts/...
www.huber.embl.de/group/posts/...
Digital sovereignty – Huber Group @ EMBL
The US is now a mafia-style extortionist you want to stay away from
www.huber.embl.de
March 8, 2025 at 9:15 AM
It's time for individuals and organizations in Europe and other democratic countries to move mission- or life-critical IT services and infrastructure outside the reach of the US government; noting that US tech companies have already largely subordinated themselves.
www.huber.embl.de/group/posts/...
www.huber.embl.de/group/posts/...
Reposted by Jürg Bähler
Hello everyone on Bluesky! 🧪
We are EMBO, the organization of more than 2,100 leading researchers that promotes excellence in #lifesciences in Europe and beyond.
Read more: www.embo.org/about-embo/m...
We are EMBO, the organization of more than 2,100 leading researchers that promotes excellence in #lifesciences in Europe and beyond.
Read more: www.embo.org/about-embo/m...
February 12, 2025 at 12:56 PM
Hello everyone on Bluesky! 🧪
We are EMBO, the organization of more than 2,100 leading researchers that promotes excellence in #lifesciences in Europe and beyond.
Read more: www.embo.org/about-embo/m...
We are EMBO, the organization of more than 2,100 leading researchers that promotes excellence in #lifesciences in Europe and beyond.
Read more: www.embo.org/about-embo/m...
Reposted by Jürg Bähler
Grant rejections got you feeling low?
BSRA research grants have success rates between 35-67%! We offer our members
- Small Research Grants
- Travel Grants
- Summer Studentships
Next deadline 1st March. Know the perfect person? Tag them below!
bsra.org.uk/bsra-open-gr...
BSRA research grants have success rates between 35-67%! We offer our members
- Small Research Grants
- Travel Grants
- Summer Studentships
Next deadline 1st March. Know the perfect person? Tag them below!
bsra.org.uk/bsra-open-gr...
February 11, 2025 at 9:19 AM
Grant rejections got you feeling low?
BSRA research grants have success rates between 35-67%! We offer our members
- Small Research Grants
- Travel Grants
- Summer Studentships
Next deadline 1st March. Know the perfect person? Tag them below!
bsra.org.uk/bsra-open-gr...
BSRA research grants have success rates between 35-67%! We offer our members
- Small Research Grants
- Travel Grants
- Summer Studentships
Next deadline 1st March. Know the perfect person? Tag them below!
bsra.org.uk/bsra-open-gr...
Reposted by Jürg Bähler
'Many of us...have a feeling that we are living in a country where fanatics, hooligans and eccentrics have got the upper hand.'
British Ambassador to Berlin, 1933.
British Ambassador to Berlin, 1933.
January 21, 2025 at 5:27 PM
'Many of us...have a feeling that we are living in a country where fanatics, hooligans and eccentrics have got the upper hand.'
British Ambassador to Berlin, 1933.
British Ambassador to Berlin, 1933.
You can apply to our postdoc position until 12 Jan:
We are looking for a Postdoc in Functional Genomics to examine the roles of conserved yet unstudied proteins, focusing on cellular quiescence and ageing.
www.ucl.ac.uk/work-at-ucl/...
We are looking for a Postdoc in Functional Genomics to examine the roles of conserved yet unstudied proteins, focusing on cellular quiescence and ageing.
www.ucl.ac.uk/work-at-ucl/...
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
www.ucl.ac.uk
January 5, 2025 at 4:19 PM
You can apply to our postdoc position until 12 Jan:
We are looking for a Postdoc in Functional Genomics to examine the roles of conserved yet unstudied proteins, focusing on cellular quiescence and ageing.
www.ucl.ac.uk/work-at-ucl/...
We are looking for a Postdoc in Functional Genomics to examine the roles of conserved yet unstudied proteins, focusing on cellular quiescence and ageing.
www.ucl.ac.uk/work-at-ucl/...
Reposted by Jürg Bähler
Second PhD project now online, co-supervised by @jbahler.bsky.social. Join us to work on the genetic architecture of environmental responses in fission yeast. Tons of existing data and resources (wild strains, MA lines, evolved populations...) to dig into.
www.trees-dla.ac.uk/projects/evo...
www.trees-dla.ac.uk/projects/evo...
The evolution of environmental responses | TREES DLA
Organisms are subject to environmental conditions that vary over time and space. To gain maximum fitness in the face of this variability, they need to adapt their phenotypes in such a way as to expres...
www.trees-dla.ac.uk
December 18, 2024 at 9:34 AM
Second PhD project now online, co-supervised by @jbahler.bsky.social. Join us to work on the genetic architecture of environmental responses in fission yeast. Tons of existing data and resources (wild strains, MA lines, evolved populations...) to dig into.
www.trees-dla.ac.uk/projects/evo...
www.trees-dla.ac.uk/projects/evo...
Reposted by Jürg Bähler
There is competitive #PhD funding for 4 years (eligibility criteria apply) to do a project on the human pathogen Candidozyma (Candida) auris dissecting the genetic basis of its antimicrobial resistance #AMR www.findaphd.com/phds/project... - pls repost
EASTBIO: Harnessing Transposon Mutagenesis to Dissect Antifungal Drug Resistance in the Fungal “Superbug” Candidozyma auris at University of Aberdeen on FindAPhD.com
PhD Project - EASTBIO: Harnessing Transposon Mutagenesis to Dissect Antifungal Drug Resistance in the Fungal “Superbug” Candidozyma auris at University of Aberdeen , listed on FindAPhD.com
www.findaphd.com
December 13, 2024 at 2:52 PM
There is competitive #PhD funding for 4 years (eligibility criteria apply) to do a project on the human pathogen Candidozyma (Candida) auris dissecting the genetic basis of its antimicrobial resistance #AMR www.findaphd.com/phds/project... - pls repost
Reposted by Jürg Bähler
OK Pinterest, I see where you are coming from
December 13, 2024 at 8:18 PM
OK Pinterest, I see where you are coming from