Jay Hinton
@jayhinton.bsky.social
Salmonella admirer & Prof of Microbiology - Working on Salmonella bloodstream infections (iNTS) in sub- Saharan Africa context. Functional genomics. T1D.
🙏 Michael 🙏
We are indebted to our co-applicant Malick Gibani @mgibani.bsky.social and his team
Malick leads the crucial Wellcome-funded CHANTS Salmonella human challenge trial that underpins our new project and made it all possible❗️
@wellcometrust.bsky.social
bmjopen.bmj.com/content/14/1...
We are indebted to our co-applicant Malick Gibani @mgibani.bsky.social and his team
Malick leads the crucial Wellcome-funded CHANTS Salmonella human challenge trial that underpins our new project and made it all possible❗️
@wellcometrust.bsky.social
bmjopen.bmj.com/content/14/1...
Protocol for the challenge non-typhoidal Salmonella (CHANTS) study: a first-in-human, in-patient, double-blind, randomised, safety and dose-escalation controlled human infection model in the UK
Introduction Invasive non-typhoidal Salmonella (iNTS) serovars are a major cause of community-acquired bloodstream infections in sub-Saharan Africa (SSA). In this setting, Salmonella enterica serovar ...
bmjopen.bmj.com
November 6, 2025 at 7:21 AM
🙏 Michael 🙏
We are indebted to our co-applicant Malick Gibani @mgibani.bsky.social and his team
Malick leads the crucial Wellcome-funded CHANTS Salmonella human challenge trial that underpins our new project and made it all possible❗️
@wellcometrust.bsky.social
bmjopen.bmj.com/content/14/1...
We are indebted to our co-applicant Malick Gibani @mgibani.bsky.social and his team
Malick leads the crucial Wellcome-funded CHANTS Salmonella human challenge trial that underpins our new project and made it all possible❗️
@wellcometrust.bsky.social
bmjopen.bmj.com/content/14/1...
to @edcoakes.bsky.social and the CGR team for mastering vast metagenomic and metatranscriptomic datasets; to @roygoodacre.bsky.social and his colleagues at the CMR for their next-level metabolomic insights; to @acdarby.bsky.social and to @livuni-livsrf.bsky.social
October 30, 2025 at 3:50 PM
to @edcoakes.bsky.social and the CGR team for mastering vast metagenomic and metatranscriptomic datasets; to @roygoodacre.bsky.social and his colleagues at the CMR for their next-level metabolomic insights; to @acdarby.bsky.social and to @livuni-livsrf.bsky.social
We’re especially grateful to Wolf-Dietrich Hardt & @mgibani.bsky.social for suggesting the idea; to @lisamaierlab.bsky.social for bringing her remarkable TurboFerm high-throughput fermenter technology; to @blancaps.bsky.social for her expertise in Salmonella genomics and transcriptomics;
October 30, 2025 at 3:50 PM
We’re especially grateful to Wolf-Dietrich Hardt & @mgibani.bsky.social for suggesting the idea; to @lisamaierlab.bsky.social for bringing her remarkable TurboFerm high-throughput fermenter technology; to @blancaps.bsky.social for her expertise in Salmonella genomics and transcriptomics;
Bringing this together required a truly multidisciplinary effort — combining expertise with human challenge models, Salmonella–microbiota interactions, Salmonella biology and advanced multi-omics approaches including metagenomics, metatranscriptomics, and metabolomics.
October 30, 2025 at 3:50 PM
Bringing this together required a truly multidisciplinary effort — combining expertise with human challenge models, Salmonella–microbiota interactions, Salmonella biology and advanced multi-omics approaches including metagenomics, metatranscriptomics, and metabolomics.
We believe that this colonisation resistance is driven by the human gut microbiota -we will test our hypotheses experimentally & aim to define the mechanisms involved
The exciting project builds on outstanding work of @mgibani.bsky.social & team who developed Salmonella CHANTS human challenge model
The exciting project builds on outstanding work of @mgibani.bsky.social & team who developed Salmonella CHANTS human challenge model
October 30, 2025 at 3:50 PM
We believe that this colonisation resistance is driven by the human gut microbiota -we will test our hypotheses experimentally & aim to define the mechanisms involved
The exciting project builds on outstanding work of @mgibani.bsky.social & team who developed Salmonella CHANTS human challenge model
The exciting project builds on outstanding work of @mgibani.bsky.social & team who developed Salmonella CHANTS human challenge model
Welcome to Liverpool Tanya ❗️
September 19, 2025 at 8:36 AM
Welcome to Liverpool Tanya ❗️