Jan Böhning
@janboehning.bsky.social
Postdoc, MRC-LMB. Cryo-EM/ET, mycobacteria, biofilms
Reposted by Jan Böhning
Assembly, architecture and functional roles of microbial surface layers
Review article published in @natrevmicro.nature.com with @bupbuse.bsky.social, Andriko von Kügelgen and @vikramalva.bsky.social.
S-layers are everywhere!
www.nature.com/articles/s41...
Review article published in @natrevmicro.nature.com with @bupbuse.bsky.social, Andriko von Kügelgen and @vikramalva.bsky.social.
S-layers are everywhere!
www.nature.com/articles/s41...
Assembly, architecture and functional roles of microbial surface layers - Nature Reviews Microbiology
Surface layers (S-layers) are ubiquitous protein assemblies that coat prokaryotic cells, with their functional roles increasingly coming into focus. In this Review, Isbilir and colleagues discuss rece...
www.nature.com
November 13, 2025 at 8:14 PM
Assembly, architecture and functional roles of microbial surface layers
Review article published in @natrevmicro.nature.com with @bupbuse.bsky.social, Andriko von Kügelgen and @vikramalva.bsky.social.
S-layers are everywhere!
www.nature.com/articles/s41...
Review article published in @natrevmicro.nature.com with @bupbuse.bsky.social, Andriko von Kügelgen and @vikramalva.bsky.social.
S-layers are everywhere!
www.nature.com/articles/s41...
Reposted by Jan Böhning
Sub-cellular chemical mapping in bacteria using correlated cryogenic electron and mass spectrometry imaging
Congrats Hannah Ochner and authors on this important paper! Strong collaboration with @kiranrpatil.bsky.social
www.biorxiv.org/cgi/content/...
@mrclmb.bsky.social @wellcometrust.bsky.social
Congrats Hannah Ochner and authors on this important paper! Strong collaboration with @kiranrpatil.bsky.social
www.biorxiv.org/cgi/content/...
@mrclmb.bsky.social @wellcometrust.bsky.social
August 31, 2025 at 6:44 PM
Sub-cellular chemical mapping in bacteria using correlated cryogenic electron and mass spectrometry imaging
Congrats Hannah Ochner and authors on this important paper! Strong collaboration with @kiranrpatil.bsky.social
www.biorxiv.org/cgi/content/...
@mrclmb.bsky.social @wellcometrust.bsky.social
Congrats Hannah Ochner and authors on this important paper! Strong collaboration with @kiranrpatil.bsky.social
www.biorxiv.org/cgi/content/...
@mrclmb.bsky.social @wellcometrust.bsky.social
Reposted by Jan Böhning
Targeted disruption of phage liquid crystalline droplets abolishes antibiotic tolerance of bacterial biofilms
led by @abultarafder.bsky.social
Great collaboration with @pearce-maths.bsky.social and @geiselbiofilm.bsky.social
www.biorxiv.org/cgi/content/...
led by @abultarafder.bsky.social
Great collaboration with @pearce-maths.bsky.social and @geiselbiofilm.bsky.social
www.biorxiv.org/cgi/content/...
July 29, 2025 at 9:35 AM
Targeted disruption of phage liquid crystalline droplets abolishes antibiotic tolerance of bacterial biofilms
led by @abultarafder.bsky.social
Great collaboration with @pearce-maths.bsky.social and @geiselbiofilm.bsky.social
www.biorxiv.org/cgi/content/...
led by @abultarafder.bsky.social
Great collaboration with @pearce-maths.bsky.social and @geiselbiofilm.bsky.social
www.biorxiv.org/cgi/content/...
Reposted by Jan Böhning
Bedaquiline resistance driven by the MmpS5L5 efflux pump is threatening the drug regimens used to treat MDR-TB.
In our new preprint, we used structural and genetic approaches to better understand how MmpS5L5 effluxes bedaquiline and how future resistance may evolve. 🧵🔽
#TBsky #MicroSky #TB
In our new preprint, we used structural and genetic approaches to better understand how MmpS5L5 effluxes bedaquiline and how future resistance may evolve. 🧵🔽
#TBsky #MicroSky #TB
Structural and functional analysis of the Mycobacterium tuberculosis MmpS5L5 efflux pump presages a pathway to increased bedaquiline resistance
Bedaquiline, an antitubercular drug that targets ATP-synthase, is a key component of a new oral drug regimen that has revolutionized the treatment of multi drug resistant tuberculosis. Clinical bedaqu...
www.biorxiv.org
June 26, 2025 at 10:30 AM