James Gagnon
@james-gagnon.bsky.social
I'm an associate professor @UofUBiology, Utah, USA
gagnonlab.org | fish stuff in and out of the tank
gagnonlab.org | fish stuff in and out of the tank
Ooo fun! How about hox conservation
July 31, 2025 at 4:06 PM
Ooo fun! How about hox conservation
Development is coordinated by interactions between cell types, but these effects are often missed in cultured cell studies.
We developed an approach to identify these “cell-extrinsic effects” and discovered that they were pervasive in our dataset, actually outnumbering cell-intrinsic effects!
We developed an approach to identify these “cell-extrinsic effects” and discovered that they were pervasive in our dataset, actually outnumbering cell-intrinsic effects!
June 2, 2025 at 4:13 PM
Development is coordinated by interactions between cell types, but these effects are often missed in cultured cell studies.
We developed an approach to identify these “cell-extrinsic effects” and discovered that they were pervasive in our dataset, actually outnumbering cell-intrinsic effects!
We developed an approach to identify these “cell-extrinsic effects” and discovered that they were pervasive in our dataset, actually outnumbering cell-intrinsic effects!
In one experiment, we mutated 50 transcription factors and measured the consequences to 74 cell types across ~1000 embryos.
We found a lot of cool things, including many new phenotypes that we could confirm with other methods.
We found a lot of cool things, including many new phenotypes that we could confirm with other methods.
June 2, 2025 at 4:13 PM
In one experiment, we mutated 50 transcription factors and measured the consequences to 74 cell types across ~1000 embryos.
We found a lot of cool things, including many new phenotypes that we could confirm with other methods.
We found a lot of cool things, including many new phenotypes that we could confirm with other methods.