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JAMA Dermatology
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JAMA Dermatology is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications.

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In Sézary syndrome, detectable minimal residual disease at remission via high-throughput sequencing is linked to greater relapse risk. ja.ma/4p7hnyi
December 1, 2025 at 1:00 PM
In patients with #psoriatic #arthritis, combination targeted therapy does not significantly increase the risk of serious or opportunistic infections compared to standard therapy. ja.ma/3M1Vy4z
November 30, 2025 at 1:00 PM
This case report describes a woman in her 30s with porcelain-white discoloration of all nails, which persisted under pressure, and a GJA1 mutation.

ja.ma/4prvTRa
November 29, 2025 at 3:00 PM
A woman in her 50s presented with a nodular lesion on her left cheek. MRI revealed a well-defined, hypervascular, solid tumor located within the subcutaneous tissue with no evidence of invasion into adjacent structures.

What is your diagnosis? ja.ma/3XjbQbM
November 29, 2025 at 1:00 PM
On December 1 at 10 AM ET, JAMA and JAMA Network Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, will co-chair a public, live-streamed webinar discussing a new @who.int guideline concerning #GLP-1 therapy and adults with #obesity.

Register for the webinar: ja.ma/4irk1MR
November 28, 2025 at 6:36 PM
Analysis of Global Burden of Disease data from 1990 to 2021 shows a gradual rise in #psoriasis incidence for both sexes worldwide, with projections indicating continued increases by 2050.

ja.ma/4p24gOI
November 28, 2025 at 3:00 PM
A semiautomatic UV reflectance image-based system is comparably reliable to conventional methods for assessing vitiligo lesions using the Vitiligo Area Scoring Index (VASI).

ja.ma/4oV1wCO
November 28, 2025 at 1:00 PM
A community-based cohort study found progression to severe hidradenitis suppurativa is 10.4 times lower and remission rates are 3.8 times higher than hospital-based estimates.

ja.ma/4oVxGOw
November 27, 2025 at 3:00 PM
Hidradenitis suppurativa (HS) is a chronic, inflammatory condition in which nearly half of affected individuals experience psychiatric comorbidities.

This systematic review examines existing evidence on the relationship between disordered eating and HS.

ja.ma/3M0mEsY
November 27, 2025 at 1:00 PM
On December 1 at 10 AM ET, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, will co-chair a public, live-streamed webinar discussing a new WHO guideline concerning #GLP-1 therapy and adults with #obesity.

Register for the webinar: ja.ma/3KlWQH7
November 26, 2025 at 5:00 PM
A modified Delphi process achieved consensus on detailed morphologic definitions for 11 HS lesion types and 16 guidance statements to standardize lesion assessment in clinical trials.

ja.ma/44wm0JM
November 26, 2025 at 5:00 PM
JAK2 fusions in cutaneous T-cell lymphomas are present in both aggressive and indolent disease, including patients with early-stage mycosis fungoides and CD30-positive lymphoproliferative disorders.

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November 26, 2025 at 4:30 PM
#Sunburn history, especially painful, blistering, or severe sunburns during childhood or across a lifetime, is associated with increased odds of developing cutaneous squamous cell #carcinoma. ja.ma/44poUQB
November 26, 2025 at 1:00 PM
Editorial: #Nicotinamide shows significant promise as a chemopreventive agent to reduce skin cancer risk in those with a history of the disease, advocating for its integration into routine secondary prevention alongside sun protection.

ja.ma/4rqHguA
November 25, 2025 at 7:38 PM
In this cohort study of Merkel cell #carcinoma patients, a falling or negative titer indicated a 99.3% chance of remaining recurrence-free over 3 months, while a rising oncoprotein antibody titer suggested a 58% risk of recurrence by 12 months. ja.ma/4rifJeA
November 24, 2025 at 3:00 PM
The use of #nicotinamide is associated with a reduced risk of developing skin #cancer, particularly when initiated after the first skin cancer. ja.ma/48cXn5V
November 24, 2025 at 1:00 PM
A new prediction tool for #melanoma developed from the long-running QSkin Study was found to estimate future risk with high accuracy. ja.ma/3XJDBu4
November 23, 2025 at 1:00 PM
Among adults treated with #adalimumab, those with hidradenitis suppurativa have a higher risk of hospitalization due to noncutaneous infections, sepsis, and genitourinary infections. ja.ma/43F7Juc
November 22, 2025 at 2:00 PM
💬 Viewpoint: #AI is rapidly transforming dermatology training, yet most residency programs lack dedicated curricula and policies for guiding responsible use and integration into practice.

ja.ma/47UyEEN
November 22, 2025 at 12:00 PM
No statistically significant association was found between the initiation of interleukin (IL)-17(R)A inhibitors and major adverse cardiovascular events in patients, with tumor necrosis factor-α inhibitors used as comparators. ja.ma/47SreSn
November 21, 2025 at 2:00 PM
A woman in her 30s presented to our department with a 1-year history of painful annular eruptions on the anterior neck. What is your diagnosis?

ja.ma/48aN96i
November 21, 2025 at 12:00 PM
This case report describes a patient with a history of refractory acute myeloid leukemia who presented with white, spiny hyperkeratotic papules on his face and neck, and was subsequently diagnosed with trichodysplasia spinulosa. ja.ma/4pkNRVs
November 20, 2025 at 2:00 PM
Substituting roflumilast for apremilast in #psoriatic disease from 2014-2024 may have saved the US health system up to $13.5 billion.

ja.ma/3JYYZbG
November 20, 2025 at 12:00 PM
JAK inhibitor exposure was not associated with reduced height in children treated for atopic dermatitis, juvenile arthritis, or inflammatory bowel disease.

ja.ma/4nSUJZb
November 16, 2025 at 4:00 PM
A 12-year-old boy was referred to the dermatology clinic with a nonprogressive hyperpigmented and indurated plaque on his right forearm for 5 years.

What is your diagnosis?

ja.ma/4oIfAj9
November 16, 2025 at 3:00 PM