jacobboysen.bsky.social
jacobboysen.bsky.social
@jacobboysen.bsky.social
The liminal space between self and non-self. AI x genome grammars. Noncoding, TEs, UTRs, that sort of thing.
Autosomes, not autonomies lol
March 12, 2025 at 6:06 AM
Is it common to have these y-chromosome-like fixed non-recombining regions across plant autonomies? Plants you crazy bastards….
March 12, 2025 at 6:05 AM
Plants are nuts, your work is really cool. I haven’t spent a lot of time with your papers so apologies for ignorance, but just perusing, it looks like 3’UTR repeats are a dominant theme? And evidence for small RNAs or possibly (I assume) some other trans factor being the limiting timing factor?
March 12, 2025 at 6:04 AM
I love the idea anchor species but I wonder if they need to be tied phylogenetically or if they need to based off genome architecture characteristics. Yeast and fission yeast and candida for example, very different genome architectures due to ecology and domestication etc
March 6, 2025 at 1:19 AM
Right right, so this matches my mental model as well. We’re trying to brute force speak genome Esperanto when we barely speak a few genome languages “well”. Compared to proteins where the language is the same across all species essentially
March 6, 2025 at 1:16 AM
What do you mean by better labels and tricks? Much higher quality annotation of ref genomes?
March 6, 2025 at 12:23 AM
Are these SINE fossils? Ie do they have limited seq complementarity? You can….go down a really big rabbit hole here
December 12, 2024 at 4:34 PM