Infectious Diseases Fellowship at Indiana University
@iuidfellowship.bsky.social
#idboardreview #idfellows #idfellowship #IDsky #HIVsky #idmeded
rabies #PEP ref www.cdc.gov/rabies/hcp/c...
Rabies Post-exposure Prophylaxis Guidance
Necessary steps to take when a patient has been exposed to rabies.
www.cdc.gov
December 11, 2025 at 12:59 AM
rabies #PEP ref www.cdc.gov/rabies/hcp/c...
skunks are not a #rabies virus reservoir in Idaho, bat-maintained rabies virus variants, including silver-haired bat variant, are enzootic in the state.
likely 3-step transmission chain: rabid silver-haired bat infected a skunk, which infected donor & led to infection of transplant recipient
likely 3-step transmission chain: rabid silver-haired bat infected a skunk, which infected donor & led to infection of transplant recipient
December 11, 2025 at 12:56 AM
skunks are not a #rabies virus reservoir in Idaho, bat-maintained rabies virus variants, including silver-haired bat variant, are enzootic in the state.
likely 3-step transmission chain: rabid silver-haired bat infected a skunk, which infected donor & led to infection of transplant recipient
likely 3-step transmission chain: rabid silver-haired bat infected a skunk, which infected donor & led to infection of transplant recipient
#Rabies risk varies by species, geography, & exposure circumstances. Rabies virus is maintained by specific animal reservoir species in continental USA (i.e., bats, raccoons, skunks, and foxes); however, any mammal can be infected, and approximately 800 cross-species infections were reported in 2022
December 11, 2025 at 12:54 AM
#Rabies risk varies by species, geography, & exposure circumstances. Rabies virus is maintained by specific animal reservoir species in continental USA (i.e., bats, raccoons, skunks, and foxes); however, any mammal can be infected, and approximately 800 cross-species infections were reported in 2022
5 weeks post-skunk scratch: donor was confused, had difficulty swallowing/walking, hallucinations, and a stiff neck. 2d later unresponsive: hospitalized: never regained consciousness & declared brain dead/removed from life support on hospital day 5.
December 11, 2025 at 12:51 AM
5 weeks post-skunk scratch: donor was confused, had difficulty swallowing/walking, hallucinations, and a stiff neck. 2d later unresponsive: hospitalized: never regained consciousness & declared brain dead/removed from life support on hospital day 5.
Per family: a skunk approached the donor as he held a kitten in an outbuilding on his rural property. The donor sustained a shin scratch that bled, but he did not think he had been bitten. According to the family, the donor attributed the skunk’s behavior to predatory aggression toward the kitten.
December 11, 2025 at 12:50 AM
Per family: a skunk approached the donor as he held a kitten in an outbuilding on his rural property. The donor sustained a shin scratch that bled, but he did not think he had been bitten. According to the family, the donor attributed the skunk’s behavior to predatory aggression toward the kitten.
#Rabies Human-to-Human Rabies Transmission via Solid Organ Transplantation from a Donor with Undiagnosed Rabies — United States, October 2024–February 2025 www.cdc.gov/mmwr/volumes...
Human-to-Human Rabies Transmission via Solid Organ...
This report describes the public health response to a patient who died after transplantation with an organ from a donor with undiagnosed rabies.
www.cdc.gov
December 11, 2025 at 12:48 AM
#Rabies Human-to-Human Rabies Transmission via Solid Organ Transplantation from a Donor with Undiagnosed Rabies — United States, October 2024–February 2025 www.cdc.gov/mmwr/volumes...
Treatment consisted primarily of surgery (94%) often in combination with antibiotics (77%). Only 11 cases were treated solely with antibiotics. PMID: 30755846
December 9, 2025 at 11:40 PM
Treatment consisted primarily of surgery (94%) often in combination with antibiotics (77%). Only 11 cases were treated solely with antibiotics. PMID: 30755846
December 9, 2025 at 11:40 PM
#penumbra sign has a high specificity of 96% but low sensitivity of 27% for musculoskeletal infections & helpful in differentiating neoplasm from infection. The proximal tibia is most frequent site of involvement & Staphylococcus aureus is the most commonly identified pathogen
December 9, 2025 at 11:38 PM
#penumbra sign has a high specificity of 96% but low sensitivity of 27% for musculoskeletal infections & helpful in differentiating neoplasm from infection. The proximal tibia is most frequent site of involvement & Staphylococcus aureus is the most commonly identified pathogen
#Penumbra sign: characteristic MRI feature of subacute osteomyelitis but can be seen in tuberculosis osteitis, osteoid osteoma, chondrosarcoma, eosinophilic granuloma as well as in benign cystic neoplasm and intraosseous ganglion
December 9, 2025 at 11:38 PM
#Penumbra sign: characteristic MRI feature of subacute osteomyelitis but can be seen in tuberculosis osteitis, osteoid osteoma, chondrosarcoma, eosinophilic granuloma as well as in benign cystic neoplasm and intraosseous ganglion
rim of tissue lining an abscess cavity in proximal metaphysis with minor signal hyperintensity relative to main abscess contents on T1: “penumbra sign” #brodie’s abscess most common cause staph aureus
December 9, 2025 at 11:38 PM
rim of tissue lining an abscess cavity in proximal metaphysis with minor signal hyperintensity relative to main abscess contents on T1: “penumbra sign” #brodie’s abscess most common cause staph aureus
#idboardreview Mycobacterium #bovis intrinsic Resistant to pyrazinamide. Tx: rifampicin, isoniazid & ethambutol x9mo #idsky
December 9, 2025 at 12:44 AM
#idboardreview Mycobacterium #bovis intrinsic Resistant to pyrazinamide. Tx: rifampicin, isoniazid & ethambutol x9mo #idsky
-High risk (contact w/ livestock closed spaces) abattoir workers, vet cattle necropsies foremen & milkers
-Medium risk (contact w/ livestock open spaces) tractor op, herders, feeders, vet & living in cowshed
-low risk (no direct w/ livestock)cowshed owners,clerks #bovis #TB
-Medium risk (contact w/ livestock open spaces) tractor op, herders, feeders, vet & living in cowshed
-low risk (no direct w/ livestock)cowshed owners,clerks #bovis #TB
December 9, 2025 at 12:44 AM
Widespread milk pasteurisation and strict hygiene measures in livestock management have gradually reduced transmission of bovine tuberculosis in developed countries #bovis
December 9, 2025 at 12:43 AM
Widespread milk pasteurisation and strict hygiene measures in livestock management have gradually reduced transmission of bovine tuberculosis in developed countries #bovis
#Mycobacterium #bovis responsible for zoonotic #TB. In humans: occurs following consumption of unpasteurised dairy products. However, transmission via occupational exposure may occur via inhalation of aerosols exhaled by infected animals or humans & from direct contacts w/wound
December 9, 2025 at 12:43 AM
#Mycobacterium #bovis responsible for zoonotic #TB. In humans: occurs following consumption of unpasteurised dairy products. However, transmission via occupational exposure may occur via inhalation of aerosols exhaled by infected animals or humans & from direct contacts w/wound