We just uploaded a preprint on a new massively parallel single-molecule force spectroscopy method. No beads, no messy calibration - just pure DNA tethers pulling individual molecules while we watch them in real-time with fluorescence.
Check it out: www.biorxiv.org/content/10.1...

Latest from the lab: 🧬 Decoy DNA 🧬 can extend the lifetime of DNA-based tension probes >24h by outcompeting DNases and preserving signal integrity in live-cell tension imaging. This is a simple, general strategy for robust mechanobiology in DNase-rich environments. doi.org/10.1002/anie...

Wonderful visit to the University of Lethbridge -many thanks to Trushar @trushar7.bsky.social and Dylan for the kind hosting! Great discussions with researchers at the Chemistry and Biochemistry Department! 👍

Taking the group out for fun outside of the #BSC2025 @biophyscanada.bsky.social annual meeting, visited Niagara Falls, ran into a filming of a featured film, good times!

Congratulations 🎉 to Ryan, David, and Irving for winning two poster and a travel award at the @biophyscanada.bsky.social annual meeting! 👏

We just published a review of the very recent progress in integrin force loading rate measurement using various molecular tension probes. Learn more about how this has advanced the field and what potential improvement lies ahead here: doi.org/10.1017/qrd....
#mechanobiology #integrin #tensionprobes

Hello little one, nice to meet you!
#daimon

This is immensely fun to read
doi.org/10.1016/j.ij...

Coffee…made
Matlab…opened
Meetings…none
It’s gonna be a great day!