Roisin OFlaherty
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irishglycogirl.bsky.social
Roisin OFlaherty
@irishglycogirl.bsky.social
76 followers 150 following 3 posts
Lecturer of Chemistry, PI in Glycoscience, Chair of Jenner Glycobiology and Medicine Symposium 2025, Mom and Musician
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irishglycogirl.bsky.social
Delighted to share our latest publication in Advanced Science, where we show that hypersialylation is a key feature of intervertebral disc degeneration and that inhibiting this glycosylation change can modulate inflammatory and metabolic pathways.

doi.org/10.1002/advs...
Inhibition of Hypersialylation in Human Intervertebral Disc Degeneration Modulates Inflammation and Metabolism
Glycosylation, specifically hypersialylation, is identified as a critical factor in human intervertebral disc (IVD) degeneration—a major cause of low back pain. This study demonstrates that inhibitin....
doi.org
November 21, 2025 at 5:30 PM
irishglycogirl.bsky.social
🚨 New paper in Glycobiology! 🚨
Thrilled to share our latest work on serum glycosylation in nephropathic cystinosis and the understudied IgG glycosylation in juveniles.

Read it here: academic.oup.com/glycob/artic...

#Glycoscience #Glycobiology #RareDisease #Biomarkers #TeamMaynooth
August 27, 2025 at 10:17 AM