La segunda ronda de keynote talks nos trae expertos/as del ICTP-CSIC, @uahes.bsky.social, IMDEA nanociencia, @iqf-csic.bsky.social y el propio @iqm-csic.bsky.social, que nos han hablado de nanotecnologías aplicadas a la medicina y del impacto de la IA en la biología estructural
#Innovación #Ciencia

A continuación, María Llorens-Martín, del @cbm-csic-uam.bsky.social, nos habla sobre la neurogénesis hipocampal adulta: la incorporación de nuevas neuronas a lo largo de la vida, uno de los fenómenos más fascinantes y únicos de nuestro cerebro 🧠
@csic.es

This method enables noninvasive PET imaging of atherosclerosis without using antibodies and may have potential for targeted drug delivery to atherosclerotic plaques.

👏 Congratulations to all the authors for this remarkable contribution to nanomedicine and molecular imaging! (4/4)

#Nanomedicine

The study shows that functionalized sphingomyelin solid lipid nanoparticles accumulate in atherosclerotic plaques, enabling binding of radiolabeled nanotracers for precise PET imaging.
In mice, a clear aortic arch signal appeared only in animals receiving the complete pretargeting strategy. (3/4)

In this work, the team introduces an innovative nanoparticle-to-nanoparticle pretargeted #PET imaging strategy for the noninvasive detection of #atherosclerosis — a fully nanomaterial-based approach that eliminates the need for antibodies as targeting agents. (2/4)