IorioLab
@ioriolab.bsky.social
we mix informatics/biology/functional-genomics to identify new therapeutic targets/markers, for cancer and other human diseases. we ❤️ CRISPR, statistics and ML
@eurocancerdepmap.bsky.social, hosted by Francesco (alongside Pedro Beltrao from ETH Zurich, and Evangelia Petsalaki and Isidro Cortés-Ciriano from EMBL-EBI) at @humantechnopole.bsky.social, has concluded. Great speakers delivered breakthroughs that advance #cancer genomics across #Europe! 🏛️🧬
November 24, 2025 at 10:53 AM
@eurocancerdepmap.bsky.social, hosted by Francesco (alongside Pedro Beltrao from ETH Zurich, and Evangelia Petsalaki and Isidro Cortés-Ciriano from EMBL-EBI) at @humantechnopole.bsky.social, has concluded. Great speakers delivered breakthroughs that advance #cancer genomics across #Europe! 🏛️🧬
Now @alejandrapcelab.bsky.social is taking us through the multidimensional map of early adaptation to treatment and how targeting cell plasticity can prevent childhood cancer relapse @eurocancerdepmap.bsky.social
November 20, 2025 at 9:39 AM
Now @alejandrapcelab.bsky.social is taking us through the multidimensional map of early adaptation to treatment and how targeting cell plasticity can prevent childhood cancer relapse @eurocancerdepmap.bsky.social
We start with Carmen Herranz-Ors from @sangerinstitute.bsky.social giving us an overview of the impressive work done to generate Tumour Organoid Biobank and develop a 3D Dependency Map @eurocancerdepmap.bsky.social
November 20, 2025 at 9:26 AM
We start with Carmen Herranz-Ors from @sangerinstitute.bsky.social giving us an overview of the impressive work done to generate Tumour Organoid Biobank and develop a 3D Dependency Map @eurocancerdepmap.bsky.social
The 2nd @eurocancerdepmap.bsky.social meeting is starting with introduction from @francescoiorio.bsky.social ! Full day of exciting talks ahead. Stay with us for live updates @humantechnopole.bsky.social
November 20, 2025 at 8:59 AM
The 2nd @eurocancerdepmap.bsky.social meeting is starting with introduction from @francescoiorio.bsky.social ! Full day of exciting talks ahead. Stay with us for live updates @humantechnopole.bsky.social
Delighted to host Traver Hart (MD Anderson Cancer Center), who delivered an engaging seminar on synthetic lethality at #HumanTechnopole. He showed how bridging #CRISPR and predictive modeling can advance design and interpretation of genetic interaction screens and inform new therapeutic strategies.
November 19, 2025 at 4:58 PM
Delighted to host Traver Hart (MD Anderson Cancer Center), who delivered an engaging seminar on synthetic lethality at #HumanTechnopole. He showed how bridging #CRISPR and predictive modeling can advance design and interpretation of genetic interaction screens and inform new therapeutic strategies.
Kudos to Nevenka Radic for winning the best poster award! Very well deserved 🎉
October 29, 2025 at 1:38 PM
Kudos to Nevenka Radic for winning the best poster award! Very well deserved 🎉
Francesco Iorio’s invited talk highlights how we integrate clinically relevant mutational profiles with CRISPR functional genomics data to uncover vulnerabilities associated with mutations currently considered non-actionable, expanding potential therapeutic opportunities.
October 29, 2025 at 1:37 PM
Francesco Iorio’s invited talk highlights how we integrate clinically relevant mutational profiles with CRISPR functional genomics data to uncover vulnerabilities associated with mutations currently considered non-actionable, expanding potential therapeutic opportunities.
Vanessa Spagnolo presents how we dissect cancer dependencies using CRISPR functional genomics, and how we are applying these approaches across multiple projects in our lab to identify new therapeutic vulnerabilities.
October 29, 2025 at 1:34 PM
Vanessa Spagnolo presents how we dissect cancer dependencies using CRISPR functional genomics, and how we are applying these approaches across multiple projects in our lab to identify new therapeutic vulnerabilities.
Nevenka Radic is showcasing our work charting the genetic dependencies of drug-resistant cancer cells. By identifying context-specific vulnerabilities, we aim to inform the rational design of combinatorial treatments to advancing precision oncology.
October 29, 2025 at 1:33 PM
Nevenka Radic is showcasing our work charting the genetic dependencies of drug-resistant cancer cells. By identifying context-specific vulnerabilities, we aim to inform the rational design of combinatorial treatments to advancing precision oncology.
The Iorio Lab is at the 37th AICC International Meeting in Florence this week. With our Francesco Iorio presenting as an invited speaker, Nevenka Radic with a flash talk and Vanessa Spagnolo with a poster. Excited to share our latest results and connect with colleagues in the field.
October 29, 2025 at 1:30 PM
The Iorio Lab is at the 37th AICC International Meeting in Florence this week. With our Francesco Iorio presenting as an invited speaker, Nevenka Radic with a flash talk and Vanessa Spagnolo with a poster. Excited to share our latest results and connect with colleagues in the field.
Kudos to Nevenka Radic for winning the best poster award! Very well deserved 🎉
October 29, 2025 at 1:19 PM
Kudos to Nevenka Radic for winning the best poster award! Very well deserved 🎉
Francesco Iorio’s invited talk highlights how we integrate clinically relevant mutational profiles with CRISPR functional genomics data to uncover vulnerabilities associated with mutations currently considered non-actionable, expanding potential therapeutic opportunities.
October 29, 2025 at 1:15 PM
Francesco Iorio’s invited talk highlights how we integrate clinically relevant mutational profiles with CRISPR functional genomics data to uncover vulnerabilities associated with mutations currently considered non-actionable, expanding potential therapeutic opportunities.
Vanessa Spagnolo presents how we dissect cancer dependencies using CRISPR functional genomics, and how we are applying these approaches across multiple projects in our lab to identify new therapeutic vulnerabilities.
October 29, 2025 at 1:11 PM
Vanessa Spagnolo presents how we dissect cancer dependencies using CRISPR functional genomics, and how we are applying these approaches across multiple projects in our lab to identify new therapeutic vulnerabilities.
Nevenka Radic is showcasing our work charting the genetic dependencies of drug-resistant cancer cells. By identifying context-specific vulnerabilities, we aim to inform the rational design of combinatorial treatments to advancing precision oncology.
October 29, 2025 at 1:10 PM
Nevenka Radic is showcasing our work charting the genetic dependencies of drug-resistant cancer cells. By identifying context-specific vulnerabilities, we aim to inform the rational design of combinatorial treatments to advancing precision oncology.
Kudos to our Flavio Passante for winning with his team the REMEDi4ALL Hackathon in Barcellona! Researchers from 10 countries tackled real-world challenges in drug repurposing for rare neurodevelopmental disorders, spanning the whole pipeline from early target discovery to market access.
October 23, 2025 at 11:48 AM
Kudos to our Flavio Passante for winning with his team the REMEDi4ALL Hackathon in Barcellona! Researchers from 10 countries tackled real-world challenges in drug repurposing for rare neurodevelopmental disorders, spanning the whole pipeline from early target discovery to market access.
Our very own Raffaele Iannuzzi successfully defended his PhD Thesis last week. Raf has worked on benchmarking CRISPRdata analytical tool and predictive models leveraging bulk & single cell RNA-seq data. We will definitely miss him. We wish him all the best as new adventures await! Congrats Raf! 🎉
October 22, 2025 at 7:23 AM
Our very own Raffaele Iannuzzi successfully defended his PhD Thesis last week. Raf has worked on benchmarking CRISPRdata analytical tool and predictive models leveraging bulk & single cell RNA-seq data. We will definitely miss him. We wish him all the best as new adventures await! Congrats Raf! 🎉
!!! Less than 2 weeks left to register !!! Join us in Milan for the 2nd European Cancer Dependency Map Symposium, taking place on 20 November 2025 at Human Technopole
Cancer functional genomics; CRISPR-based screening;
AIdriven targetDiscovery and drug development
humantechnopole.it/en/trainings...
Cancer functional genomics; CRISPR-based screening;
AIdriven targetDiscovery and drug development
humantechnopole.it/en/trainings...
October 21, 2025 at 10:08 AM
!!! Less than 2 weeks left to register !!! Join us in Milan for the 2nd European Cancer Dependency Map Symposium, taking place on 20 November 2025 at Human Technopole
Cancer functional genomics; CRISPR-based screening;
AIdriven targetDiscovery and drug development
humantechnopole.it/en/trainings...
Cancer functional genomics; CRISPR-based screening;
AIdriven targetDiscovery and drug development
humantechnopole.it/en/trainings...
Last week we had the pleasure of hosting @maxbillmann.bsky.social at @humantechnopole.bsky.social for an inspiring seminar on genetic interaction maps an networks. Fantastic to learn how CRISPR screens and integrative analyses can illuminate the logic of genetic dependencies. A big thank you Max 👏
October 21, 2025 at 8:57 AM
Last week we had the pleasure of hosting @maxbillmann.bsky.social at @humantechnopole.bsky.social for an inspiring seminar on genetic interaction maps an networks. Fantastic to learn how CRISPR screens and integrative analyses can illuminate the logic of genetic dependencies. A big thank you Max 👏
Today we bid farewell to our postDoc @aurorasavino.bsky.social, who is moving to an independent position at the University of Torino. Her talent dedication and collaborative spirit have left a lasting mark on our team and projects🎉
Wishing you all the best for this exciting next chapter, Aurora!
🥳🍾
Wishing you all the best for this exciting next chapter, Aurora!
🥳🍾
September 11, 2025 at 12:33 PM
Today we bid farewell to our postDoc @aurorasavino.bsky.social, who is moving to an independent position at the University of Torino. Her talent dedication and collaborative spirit have left a lasting mark on our team and projects🎉
Wishing you all the best for this exciting next chapter, Aurora!
🥳🍾
Wishing you all the best for this exciting next chapter, Aurora!
🥳🍾
we are at #EACR2025 with two posters - the second one is presented by Ludovica Proietti and Gianluca vozza and focuses on our ERC funded DEPshock project
@humantechnopole.bsky.social
@humantechnopole.bsky.social
June 18, 2025 at 11:57 AM
we are at #EACR2025 with two posters - the second one is presented by Ludovica Proietti and Gianluca vozza and focuses on our ERC funded DEPshock project
@humantechnopole.bsky.social
@humantechnopole.bsky.social
we are at #EACR2025 with two posters, one presented by our Ottavio Croci on our collaborative work around a CRISPR based prioritisation of lncRNA vulnerabilities in multiple myeloma @humantechnopole.bsky.social
June 18, 2025 at 7:32 AM
we are at #EACR2025 with two posters, one presented by our Ottavio Croci on our collaborative work around a CRISPR based prioritisation of lncRNA vulnerabilities in multiple myeloma @humantechnopole.bsky.social
Big thanks to @floriangrebien.bsky.social for a fantastic seminar yesterday at @humantechnopole.bsky.social 🔬🧬 a masterclass in dissecting AML vulnerabilities with precision and creativity. We loved the science and the lunch chat too! 👏 #cancerbiology #AML #condensates
June 12, 2025 at 7:38 PM
Big thanks to @floriangrebien.bsky.social for a fantastic seminar yesterday at @humantechnopole.bsky.social 🔬🧬 a masterclass in dissecting AML vulnerabilities with precision and creativity. We loved the science and the lunch chat too! 👏 #cancerbiology #AML #condensates
🎄🎁 Secret Santa at IorioLab! 🎁🎄
Today, we swapped gifts, laughs, and maybe a few too many inside jokes during our Secret Santa exchange. From creative surprises to hilariously overwrapped packages, everyone brought the holiday cheer 👍 merry Xmas
Today, we swapped gifts, laughs, and maybe a few too many inside jokes during our Secret Santa exchange. From creative surprises to hilariously overwrapped packages, everyone brought the holiday cheer 👍 merry Xmas
December 12, 2024 at 8:23 PM
🎄🎁 Secret Santa at IorioLab! 🎁🎄
Today, we swapped gifts, laughs, and maybe a few too many inside jokes during our Secret Santa exchange. From creative surprises to hilariously overwrapped packages, everyone brought the holiday cheer 👍 merry Xmas
Today, we swapped gifts, laughs, and maybe a few too many inside jokes during our Secret Santa exchange. From creative surprises to hilariously overwrapped packages, everyone brought the holiday cheer 👍 merry Xmas