Inés
@ines-ddo.bsky.social
Postdoc at the Dunn School (University of Oxford) researching how Salmonella evades the Immune system
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We had a fantastic time today showcasing our amazing history and cutting-edge research at #OxfordOpenDoors! Visitors learnt about 100 years of medical research, the development of penicillin and our ongoing work on microbiology and AMR. Thanks to all the volunteers!
September 13, 2025 at 2:30 PM
We had a fantastic time today showcasing our amazing history and cutting-edge research at #OxfordOpenDoors! Visitors learnt about 100 years of medical research, the development of penicillin and our ongoing work on microbiology and AMR. Thanks to all the volunteers!
Great time showcasing the amazing science we do at the @dunnschool.bsky.social at #OxfordOpenDoors today!
September 13, 2025 at 1:11 PM
Great time showcasing the amazing science we do at the @dunnschool.bsky.social at #OxfordOpenDoors today!
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We have a new preprint on Salmonella effector SteE! Here we describe how kinase reprogramming drives transcriptional remodelling of the infected macrophage www.biorxiv.org/cgi/content/... - work led by @ines-ddo.bsky.social and fantastic collaboration with @peterwshill.bsky.social
Salmonella Effector SteE Reprogrammes the Macrophage Regulatory Network to Drive Specific Hyperactivation of STAT3 Target Genes
The ability of Salmonella Typhimurium to exploit macrophages as a niche for survival, replication and dissemination is central to its pathogenesis. The effector SteE, which polarises macrophages into ...
www.biorxiv.org
July 16, 2025 at 4:03 PM
We have a new preprint on Salmonella effector SteE! Here we describe how kinase reprogramming drives transcriptional remodelling of the infected macrophage www.biorxiv.org/cgi/content/... - work led by @ines-ddo.bsky.social and fantastic collaboration with @peterwshill.bsky.social
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We recently had a day of Salmonella-focused fun. Special thanks to @eadirectordndi.bsky.social and PhD student Kelvin Kerring for joining us from Kenya to discuss iNTS. All made possible via the Global hubs fund and @embo.org YIP networking fund. @jayhinton.bsky.social @katrinrittinger.bsky.social
March 18, 2025 at 11:55 AM
We recently had a day of Salmonella-focused fun. Special thanks to @eadirectordndi.bsky.social and PhD student Kelvin Kerring for joining us from Kenya to discuss iNTS. All made possible via the Global hubs fund and @embo.org YIP networking fund. @jayhinton.bsky.social @katrinrittinger.bsky.social
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How can a Salmonella effector change the specificity of a host kinase? SteE mediates kinase reprogramming via mimicry of conserved eukaryotic-like motifs- doi.org/10.1038/s443... Great collaboration with @katrinrittinger.bsky.social + big thanks to all authors & congrats to lead PDRA Ioanna Panagi!
Bacterial effectors mediate kinase reprogramming through mimicry of conserved eukaryotic motifs | EMBO reports
imageimageA virulence protein from diverse bacteria switches the amino acid specificity of the
eukaryotic kinase GSK3. This kinase reprogramming depends on several short linear
motifs that each appear...
www.embopress.org
May 13, 2025 at 8:33 AM
How can a Salmonella effector change the specificity of a host kinase? SteE mediates kinase reprogramming via mimicry of conserved eukaryotic-like motifs- doi.org/10.1038/s443... Great collaboration with @katrinrittinger.bsky.social + big thanks to all authors & congrats to lead PDRA Ioanna Panagi!
Reposted by Inés
During my PhD at @crick.ac.uk and @imperialcollegeldn.bsky.social, I explored the molecular interaction between host and pathogen. My question: How have pathogenic bacteria evolved to manipulate their host environment during infection? 🦠https://biorxiv.org/content/10.1101/2025.03.01.640964v1 1/11
March 4, 2025 at 11:49 AM
During my PhD at @crick.ac.uk and @imperialcollegeldn.bsky.social, I explored the molecular interaction between host and pathogen. My question: How have pathogenic bacteria evolved to manipulate their host environment during infection? 🦠https://biorxiv.org/content/10.1101/2025.03.01.640964v1 1/11