Avery Hinks
@hinksave.bsky.social
PhD in muscle physiology and aging, constant reader of Stephen King books
Bonus: “Addition and Loss of Serial Sarcomeres—Implications for Muscle Mechanical Function” which also helped form the lit review in my thesis
Textbook chapter in “Fundamentals of Recovery, Regeneration, and Adaptation to Exercise Stress: An Integrated Approach”
link.springer.com/chapter/10.1...
Textbook chapter in “Fundamentals of Recovery, Regeneration, and Adaptation to Exercise Stress: An Integrated Approach”
link.springer.com/chapter/10.1...
Addition and Loss of Serial Sarcomeres—Implications for Muscle Mechanical Function
A skeletal muscle’s serial sarcomere number (SSN) is tightly regulated in response to chronic stimuli associated with changes in muscle length. Decreased SSN (~20%) is observed following immobil...
link.springer.com
September 21, 2025 at 1:11 PM
Bonus: “Addition and Loss of Serial Sarcomeres—Implications for Muscle Mechanical Function” which also helped form the lit review in my thesis
Textbook chapter in “Fundamentals of Recovery, Regeneration, and Adaptation to Exercise Stress: An Integrated Approach”
link.springer.com/chapter/10.1...
Textbook chapter in “Fundamentals of Recovery, Regeneration, and Adaptation to Exercise Stress: An Integrated Approach”
link.springer.com/chapter/10.1...
May 31, 2025 at 2:51 AM
Study 5: “Submaximal eccentric training during immobilization does not prevent serial sarcomere loss or impairments in mechanical function in old or young rats”
academic.oup.com/biomedgeront...
academic.oup.com/biomedgeront...
Validate User
academic.oup.com
May 31, 2025 at 2:47 AM
Study 5: “Submaximal eccentric training during immobilization does not prevent serial sarcomere loss or impairments in mechanical function in old or young rats”
academic.oup.com/biomedgeront...
academic.oup.com/biomedgeront...
Study 4: “Submaximal eccentric resistance training increases serial sarcomere number and improves dynamic muscle performance in old rats”
physoc.onlinelibrary.wiley.com/doi/10.14814...
physoc.onlinelibrary.wiley.com/doi/10.14814...
Submaximal eccentric resistance training increases serial sarcomere number and improves dynamic muscle performance in old rats
The age-related loss of muscle mass is partly accounted for by the loss of sarcomeres in series, contributing to declines in muscle mechanical performance. Resistance training biased to eccentric con....
physoc.onlinelibrary.wiley.com
May 31, 2025 at 2:47 AM
Study 4: “Submaximal eccentric resistance training increases serial sarcomere number and improves dynamic muscle performance in old rats”
physoc.onlinelibrary.wiley.com/doi/10.14814...
physoc.onlinelibrary.wiley.com/doi/10.14814...
Study 3: “Age-related blunting of serial sarcomerogenesis and mechanical adaptations following 4 wk of maximal eccentric resistance training”
journals.physiology.org/doi/full/10....
journals.physiology.org/doi/full/10....
Age-related blunting of serial sarcomerogenesis and mechanical adaptations following 4 wk of maximal eccentric resistance training | Journal of Applied Physiology | American Physiological Society
During aging, muscles undergo atrophy, which is partly accounted for by a loss of sarcomeres in series. Serial sarcomere number (SSN) is associated with aspects of muscle mechanical function including...
journals.physiology.org
May 31, 2025 at 2:47 AM
Study 3: “Age-related blunting of serial sarcomerogenesis and mechanical adaptations following 4 wk of maximal eccentric resistance training”
journals.physiology.org/doi/full/10....
journals.physiology.org/doi/full/10....
Study 2: “Age-related differences in the loss and recovery of serial sarcomere number following disuse atrophy in rats”
skeletalmusclejournal.biomedcentral.com/articles/10....
skeletalmusclejournal.biomedcentral.com/articles/10....
Age-related differences in the loss and recovery of serial sarcomere number following disuse atrophy in rats - Skeletal Muscle
Background Older adults exhibit a slower recovery of muscle mass following disuse atrophy than young adults. At a smaller scale, muscle fibre cross-sectional area (i.e., sarcomeres in parallel) exhibi...
skeletalmusclejournal.biomedcentral.com
May 31, 2025 at 2:47 AM
Study 2: “Age-related differences in the loss and recovery of serial sarcomere number following disuse atrophy in rats”
skeletalmusclejournal.biomedcentral.com/articles/10....
skeletalmusclejournal.biomedcentral.com/articles/10....
Study 1 (under 2nd round of review currently, but here’s the pre-print): “Changes in serial sarcomere number of five hindlimb muscles across adult aging in rats”
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
www.biorxiv.org
May 31, 2025 at 2:47 AM
Study 1 (under 2nd round of review currently, but here’s the pre-print): “Changes in serial sarcomere number of five hindlimb muscles across adult aging in rats”
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
If interested, each chapter of my thesis can be read in these publications…
Literature review: “The importance of serial sarcomere addition for muscle function and the impact of aging”
journals.physiology.org/doi/full/10....
Literature review: “The importance of serial sarcomere addition for muscle function and the impact of aging”
journals.physiology.org/doi/full/10....
The importance of serial sarcomere addition for muscle function and the impact of aging | Journal of Applied Physiology | American Physiological Society
During natural aging, skeletal muscle experiences impairments in mechanical performance due, in part, to changes in muscle architecture and size, notably with a loss of muscle cross-sectional area (CS...
journals.physiology.org
May 31, 2025 at 2:47 AM
If interested, each chapter of my thesis can be read in these publications…
Literature review: “The importance of serial sarcomere addition for muscle function and the impact of aging”
journals.physiology.org/doi/full/10....
Literature review: “The importance of serial sarcomere addition for muscle function and the impact of aging”
journals.physiology.org/doi/full/10....
Thank you so much to my supervisor @geoffpower.bsky.social, my examiners, and everyone who came out to watch and support me today!
May 30, 2025 at 10:36 PM
Thank you so much to my supervisor @geoffpower.bsky.social, my examiners, and everyone who came out to watch and support me today!
Great question Karyn! That definitely reflects the joint position at fixation. These aren’t the “optimal” sarcomere length but rather the sarcomere length at 90-degree joint angles, which seems to represent a different SL for the VL compared to soleus
March 13, 2025 at 3:07 PM
Great question Karyn! That definitely reflects the joint position at fixation. These aren’t the “optimal” sarcomere length but rather the sarcomere length at 90-degree joint angles, which seems to represent a different SL for the VL compared to soleus
Need to shoutout @aurorascientific.bsky.social for their help during the initial piloting of this apparatus!
March 11, 2025 at 4:30 PM
Need to shoutout @aurorascientific.bsky.social for their help during the initial piloting of this apparatus!