The Helix Brief
@helixbrief.bsky.social
Heliix Brief delivers fast, accessible updates on the latest biomedical research. We scan new papers published in Europe PMC and bring you clear, concise digests focused on relevance and impact.
📊 Research like this, explained daily
Join researchers getting:
✓ Daily breakthroughs
✓ Expert analysis
✓ Clear summaries
Subscribe: https://helixbrief.com
Join researchers getting:
✓ Daily breakthroughs
✓ Expert analysis
✓ Clear summaries
Subscribe: https://helixbrief.com
November 17, 2025 at 10:37 AM
📊 Research like this, explained daily
Join researchers getting:
✓ Daily breakthroughs
✓ Expert analysis
✓ Clear summaries
Subscribe: https://helixbrief.com
Join researchers getting:
✓ Daily breakthroughs
✓ Expert analysis
✓ Clear summaries
Subscribe: https://helixbrief.com
These findings shed light on the fundamental physics of spin frustration in van der Waals magnetic heterostructures and have implications for the design of novel spintronic devices.
November 17, 2025 at 10:37 AM
These findings shed light on the fundamental physics of spin frustration in van der Waals magnetic heterostructures and have implications for the design of novel spintronic devices.
Remarkably, the antiferromagnetic order induces perpendicular magnetic anisotropy in the Fe5GeTe2 layer, and an unconventional out-of-plane surface spin canting state emerges, where the Fe5GeTe2 spins transition from out-of-plane near the interface to in-plane away from the interface.
November 17, 2025 at 10:37 AM
Remarkably, the antiferromagnetic order induces perpendicular magnetic anisotropy in the Fe5GeTe2 layer, and an unconventional out-of-plane surface spin canting state emerges, where the Fe5GeTe2 spins transition from out-of-plane near the interface to in-plane away from the interface.
Using advanced characterization techniques, the researchers found that the in-plane zig-zag antiferromagnetic order in NiPS3 remains robust, even in the presence of the adjacent ferromagnetic Fe5GeTe2 layer.
November 17, 2025 at 10:37 AM
Using advanced characterization techniques, the researchers found that the in-plane zig-zag antiferromagnetic order in NiPS3 remains robust, even in the presence of the adjacent ferromagnetic Fe5GeTe2 layer.
This study investigates the intriguing magnetic properties of Fe5GeTe2/NiPS3 van der Waals heterostructures.
November 17, 2025 at 10:37 AM
This study investigates the intriguing magnetic properties of Fe5GeTe2/NiPS3 van der Waals heterostructures.
📊 Research like this, explained daily
Join researchers getting:
✓ Daily breakthroughs
✓ Expert analysis
✓ Clear summaries
Subscribe: https://helixbrief.com
Join researchers getting:
✓ Daily breakthroughs
✓ Expert analysis
✓ Clear summaries
Subscribe: https://helixbrief.com
November 17, 2025 at 10:17 AM
📊 Research like this, explained daily
Join researchers getting:
✓ Daily breakthroughs
✓ Expert analysis
✓ Clear summaries
Subscribe: https://helixbrief.com
Join researchers getting:
✓ Daily breakthroughs
✓ Expert analysis
✓ Clear summaries
Subscribe: https://helixbrief.com
Notably, IA patients underwent less joint surgery and had lower rates of osteoporosis, suggesting potential disparities in access to specialized rheumatological care.
November 17, 2025 at 10:17 AM
Notably, IA patients underwent less joint surgery and had lower rates of osteoporosis, suggesting potential disparities in access to specialized rheumatological care.
However, IA patients presented at a younger age, had higher rates of comorbidities like diabetes and obesity, and experienced greater mortality, despite similar rates of extraarticular manifestations.
November 17, 2025 at 10:17 AM
However, IA patients presented at a younger age, had higher rates of comorbidities like diabetes and obesity, and experienced greater mortality, despite similar rates of extraarticular manifestations.
The researchers found that RA incidence and prevalence rates were similar between IA and non-Indigenous patients.
November 17, 2025 at 10:17 AM
The researchers found that RA incidence and prevalence rates were similar between IA and non-Indigenous patients.
This population-based cohort study examined the epidemiology and clinical outcomes of rheumatoid arthritis (RA) in the Indigenous Australian (IA) population over 30 years.
November 17, 2025 at 10:17 AM
This population-based cohort study examined the epidemiology and clinical outcomes of rheumatoid arthritis (RA) in the Indigenous Australian (IA) population over 30 years.
📊 Research like this, explained daily
Join researchers getting:
✓ Daily breakthroughs
✓ Expert analysis
✓ Clear summaries
Subscribe: https://helixbrief.com
Join researchers getting:
✓ Daily breakthroughs
✓ Expert analysis
✓ Clear summaries
Subscribe: https://helixbrief.com
November 17, 2025 at 9:57 AM
📊 Research like this, explained daily
Join researchers getting:
✓ Daily breakthroughs
✓ Expert analysis
✓ Clear summaries
Subscribe: https://helixbrief.com
Join researchers getting:
✓ Daily breakthroughs
✓ Expert analysis
✓ Clear summaries
Subscribe: https://helixbrief.com
Limitations include the use of a porcine model and the need for further validation in human subjects.
November 17, 2025 at 9:57 AM
Limitations include the use of a porcine model and the need for further validation in human subjects.
Using qCEST-derived biomarkers, a machine learning model achieved 80% accuracy in predicting pain scores, outperforming the correlation with Modic changes. This accelerated, whole-spine qCEST approach at 3T provides a promising tool for diagnosing and monitoring lower back pain.
November 17, 2025 at 9:57 AM
Using qCEST-derived biomarkers, a machine learning model achieved 80% accuracy in predicting pain scores, outperforming the correlation with Modic changes. This accelerated, whole-spine qCEST approach at 3T provides a promising tool for diagnosing and monitoring lower back pain.
The 3D steady-state qCEST method effectively differentiated healthy and injured discs, with injured discs exhibiting higher exchange rates.
November 17, 2025 at 9:57 AM
The 3D steady-state qCEST method effectively differentiated healthy and injured discs, with injured discs exhibiting higher exchange rates.
This study used a porcine model to assess lower back pain using quantitative chemical exchange saturation transfer (qCEST) imaging. Researchers compared exchange rate maps from a novel multitasking qCEST technique with conventional qCEST, finding strong agreement.
November 17, 2025 at 9:57 AM
This study used a porcine model to assess lower back pain using quantitative chemical exchange saturation transfer (qCEST) imaging. Researchers compared exchange rate maps from a novel multitasking qCEST technique with conventional qCEST, finding strong agreement.
📊 Research like this, explained daily
Join researchers getting:
✓ Daily breakthroughs
✓ Expert analysis
✓ Clear summaries
Subscribe: https://helixbrief.com
Join researchers getting:
✓ Daily breakthroughs
✓ Expert analysis
✓ Clear summaries
Subscribe: https://helixbrief.com
November 17, 2025 at 9:37 AM
📊 Research like this, explained daily
Join researchers getting:
✓ Daily breakthroughs
✓ Expert analysis
✓ Clear summaries
Subscribe: https://helixbrief.com
Join researchers getting:
✓ Daily breakthroughs
✓ Expert analysis
✓ Clear summaries
Subscribe: https://helixbrief.com
Further analyses revealed that ThT has weaker affinities for aptamers and random DNA sequences compared to SGI, and it preferentially binds to single-stranded DNA over double-stranded DNA, the opposite of SGI. Additionally, ThT can influence the binding of G-quadruplex aptamers.
November 17, 2025 at 9:37 AM
Further analyses revealed that ThT has weaker affinities for aptamers and random DNA sequences compared to SGI, and it preferentially binds to single-stranded DNA over double-stranded DNA, the opposite of SGI. Additionally, ThT can influence the binding of G-quadruplex aptamers.
In contrast, SGI exhibited responses with apparent Kd values that often deviated from the true Kd.
November 17, 2025 at 9:37 AM
In contrast, SGI exhibited responses with apparent Kd values that often deviated from the true Kd.
The researchers investigated three non-G-quadruplex aptamers and found that ThT provided consistent dissociation constant (Kd) values and fluorescence reductions, regardless of the aptamer-to-dye ratio.
November 17, 2025 at 9:37 AM
The researchers investigated three non-G-quadruplex aptamers and found that ThT provided consistent dissociation constant (Kd) values and fluorescence reductions, regardless of the aptamer-to-dye ratio.
This study compares the performance of Thioflavin T (ThT) and SYBR Green I (SGI) as probes for label-free fluorescent binding assays in the aptamer field.
November 17, 2025 at 9:37 AM
This study compares the performance of Thioflavin T (ThT) and SYBR Green I (SGI) as probes for label-free fluorescent binding assays in the aptamer field.
📊 Research like this, explained daily
Join researchers getting:
✓ Daily breakthroughs
✓ Expert analysis
✓ Clear summaries
Subscribe: https://helixbrief.com
Join researchers getting:
✓ Daily breakthroughs
✓ Expert analysis
✓ Clear summaries
Subscribe: https://helixbrief.com
November 17, 2025 at 9:17 AM
📊 Research like this, explained daily
Join researchers getting:
✓ Daily breakthroughs
✓ Expert analysis
✓ Clear summaries
Subscribe: https://helixbrief.com
Join researchers getting:
✓ Daily breakthroughs
✓ Expert analysis
✓ Clear summaries
Subscribe: https://helixbrief.com