Hanna Julienne
@hanna-julienne.bsky.social
I'm a permanent researcher @ggspasteur.bsky.social @institutpasteur.bsky.social deciphering the #genetic components of complex diseases #GWAS. Cat and art lover. #WomenInScience She/Her
This highlight the heterogeneity encompassed in the asthma umbrella diagnosis, and the molecular differences between adult-onset and childhood-onset asthma ! More detail in the full paper 📑
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Unraveling shared genetics across asthma subtypes and 81 asthma-related traits
Asthma presents clinical and biological heterogeneity.We sought to better understand asthma heterogeneity by investigating the shared genetics between…
www.sciencedirect.com
October 10, 2025 at 4:11 PM
This highlight the heterogeneity encompassed in the asthma umbrella diagnosis, and the molecular differences between adult-onset and childhood-onset asthma ! More detail in the full paper 📑
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
👧Childhood-onset asthma variants were overwhelmingly shared with:
🔸IgE levels,
🔸Eosinophil counts
(MIXeR analysis)
🔸IgE levels,
🔸Eosinophil counts
(MIXeR analysis)
October 10, 2025 at 4:11 PM
👧Childhood-onset asthma variants were overwhelmingly shared with:
🔸IgE levels,
🔸Eosinophil counts
(MIXeR analysis)
🔸IgE levels,
🔸Eosinophil counts
(MIXeR analysis)
🧑 Adult-onset asthma showed stronger genetic links to:
🔸Higher BMI
🔸Reduced lung capacity
compared to childhood-onset asthma
🔸Higher BMI
🔸Reduced lung capacity
compared to childhood-onset asthma
October 10, 2025 at 4:11 PM
🧑 Adult-onset asthma showed stronger genetic links to:
🔸Higher BMI
🔸Reduced lung capacity
compared to childhood-onset asthma
🔸Higher BMI
🔸Reduced lung capacity
compared to childhood-onset asthma
In this study, we curated 254 GWAS summary statistics to explore the shared genetic architecture between:
✔ Asthma (overall)
✔ Asthma subtypes (severity, age-of-onset)
✔ 81 related traits (spirometry, blood counts, interleukins, and more)
✔ Asthma (overall)
✔ Asthma subtypes (severity, age-of-onset)
✔ 81 related traits (spirometry, blood counts, interleukins, and more)
October 10, 2025 at 4:11 PM
In this study, we curated 254 GWAS summary statistics to explore the shared genetic architecture between:
✔ Asthma (overall)
✔ Asthma subtypes (severity, age-of-onset)
✔ 81 related traits (spirometry, blood counts, interleukins, and more)
✔ Asthma (overall)
✔ Asthma subtypes (severity, age-of-onset)
✔ 81 related traits (spirometry, blood counts, interleukins, and more)
Reposted by Hanna Julienne
Alternate stream in case the Twitch audio wasn't working for you! bsky.app/profile/stan...
Getting reports of some sound problems with our Twitch livestream.
Here's another stream while we sort out some technical difficulties!
www.youtube.com/watch?v=eemj...
Here's another stream while we sort out some technical difficulties!
www.youtube.com/watch?v=eemj...
WATCH LIVE: 'Stand up for Science' rally with Bill Nye and others at Lincoln Memorial in Washington
YouTube video by PBS NewsHour
www.youtube.com
March 7, 2025 at 5:26 PM
Alternate stream in case the Twitch audio wasn't working for you! bsky.app/profile/stan...
The march continue with a lot of people @standupforscience.bsky.social
March 7, 2025 at 1:29 PM
The march continue with a lot of people @standupforscience.bsky.social