Robert Grosse @ grosselab
@grosselab.bsky.social
all things cytoskeleton - nuclear actin dynamics and genome - nucleoskeleton and nuclear organisation - cancer cell invasion and pharmacology
@University of Freiburg
https://www.pharmakologie.uni-freiburg.de/en/i/research/grosse
@University of Freiburg
https://www.pharmakologie.uni-freiburg.de/en/i/research/grosse
It was inspiring and fun hosting Patrick Lusk @luskinglab.bsky.social as our seminar guest, here looking at cell nuclei and peppers with AFM expert Dennis @denfra.bsky.social
November 17, 2025 at 3:00 PM
It was inspiring and fun hosting Patrick Lusk @luskinglab.bsky.social as our seminar guest, here looking at cell nuclei and peppers with AFM expert Dennis @denfra.bsky.social
Svenja Ulferts @sulferts.bsky.social receiving a wonderful doctoral thesis award from our @uni-freiburg.de president 🥳🍾 - well done and well deserved!
October 22, 2025 at 2:43 PM
Svenja Ulferts @sulferts.bsky.social receiving a wonderful doctoral thesis award from our @uni-freiburg.de president 🥳🍾 - well done and well deserved!
#FluorescenceFriday : happy MitoFriday
September 26, 2025 at 2:31 PM
#FluorescenceFriday : happy MitoFriday
we found that nuclear envelope rupture triggers rapid DIAPH3 formin influx to generate a actin mesh to prevent further chromatin leakage from damaged nuclei. thanks to Pitter Huesgen @degradomics.bsky.social and @cibss.bsky.social, @chrkam.bsky.social
September 22, 2025 at 11:00 AM
we found that nuclear envelope rupture triggers rapid DIAPH3 formin influx to generate a actin mesh to prevent further chromatin leakage from damaged nuclei. thanks to Pitter Huesgen @degradomics.bsky.social and @cibss.bsky.social, @chrkam.bsky.social
cloud tsunami
September 9, 2025 at 6:17 PM
cloud tsunami
☝️and YAP binds G-actin with even higher affinity than the RPEL domain of MRTF-A (MAL, MKL1) the SRF co-activator
August 1, 2025 at 12:01 PM
☝️and YAP binds G-actin with even higher affinity than the RPEL domain of MRTF-A (MAL, MKL1) the SRF co-activator
from our 'older' paper Baarlink et al. 2017, live imaging of a dividing mouse fibroblast stably expressing a shuttling chromobody detecting actin - showing nuclear actin filaments during postmitotic nuclear expansion and chromatin decompaction as well as simultaneous membrane dynamics
June 27, 2025 at 11:07 AM
from our 'older' paper Baarlink et al. 2017, live imaging of a dividing mouse fibroblast stably expressing a shuttling chromobody detecting actin - showing nuclear actin filaments during postmitotic nuclear expansion and chromatin decompaction as well as simultaneous membrane dynamics
Great seminar and discussion with Shangqin Guo from
@yaleschoolofmed.bsky.social Department of Cell Biology on cell fate control and nuclear @actin. Science is one of the best ways to connect people from allover.
@yaleschoolofmed.bsky.social Department of Cell Biology on cell fate control and nuclear @actin. Science is one of the best ways to connect people from allover.
May 29, 2025 at 7:12 AM
Great seminar and discussion with Shangqin Guo from
@yaleschoolofmed.bsky.social Department of Cell Biology on cell fate control and nuclear @actin. Science is one of the best ways to connect people from allover.
@yaleschoolofmed.bsky.social Department of Cell Biology on cell fate control and nuclear @actin. Science is one of the best ways to connect people from allover.
it was an amazing @actin meeting in Szeged aaif2025-szeged.hu/programme/ with Stefan @raunser-lab.bsky.social as keynote + great talks covering actin in evolution, plants, muscle, endocytosis, in vitro systems and genome org. Thanks to all participants and see you at the 4th AAIF.
May 28, 2025 at 7:13 AM
it was an amazing @actin meeting in Szeged aaif2025-szeged.hu/programme/ with Stefan @raunser-lab.bsky.social as keynote + great talks covering actin in evolution, plants, muscle, endocytosis, in vitro systems and genome org. Thanks to all participants and see you at the 4th AAIF.
May 15, 2025 at 6:53 AM
To be or not to be nuclear ….
April 22, 2025 at 12:07 PM
To be or not to be nuclear ….
Nuclear F-actin in unperturbed Plasmodium falciparum using electron cryo-tomography from Josie L Ferreira lab - WOW!!
www.embopress.org/doi/full/10....
www.embopress.org/doi/full/10....
March 25, 2025 at 10:42 AM
Nuclear F-actin in unperturbed Plasmodium falciparum using electron cryo-tomography from Josie L Ferreira lab - WOW!!
www.embopress.org/doi/full/10....
www.embopress.org/doi/full/10....
please re-post! we are looking for a PhD candidate:
www.uniklinik-freiburg.de/en/career/jo...
www.uniklinik-freiburg.de/en/career/jo...
March 6, 2025 at 9:22 AM
please re-post! we are looking for a PhD candidate:
www.uniklinik-freiburg.de/en/career/jo...
www.uniklinik-freiburg.de/en/career/jo...
Very interesting study including N2G as an F-actin bundler: Active microtubule-actin cross-talk mediated by a nesprin-2G–kinesin complex | Science Advances www.science.org/doi/10.1126/...
February 25, 2025 at 9:04 AM
Very interesting study including N2G as an F-actin bundler: Active microtubule-actin cross-talk mediated by a nesprin-2G–kinesin complex | Science Advances www.science.org/doi/10.1126/...
The infamous Dr Ulferts @sulferts.bsky.social - with Distinction!! Sooo well done
February 7, 2025 at 6:23 PM
The infamous Dr Ulferts @sulferts.bsky.social - with Distinction!! Sooo well done
a Talin for DNA: Nuclear talin-1 provides a bridge between cell adhesion and gene expression.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
February 4, 2025 at 3:11 PM
a Talin for DNA: Nuclear talin-1 provides a bridge between cell adhesion and gene expression.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
January 31, 2025 at 3:28 PM
Fluorescence Friday party
January 31, 2025 at 3:15 PM
Fluorescence Friday party
won't get tired of looking at these...in case you missed it...nuclear actin assemblies with DAAM2 at ligand-stimulated androgen receptors (biomolecular condensates?)
www.nature.com/articles/s41...
we keep working to figure out all the details
www.nature.com/articles/s41...
we keep working to figure out all the details
December 21, 2024 at 10:20 AM
won't get tired of looking at these...in case you missed it...nuclear actin assemblies with DAAM2 at ligand-stimulated androgen receptors (biomolecular condensates?)
www.nature.com/articles/s41...
we keep working to figure out all the details
www.nature.com/articles/s41...
we keep working to figure out all the details
The 3rd Actin Assembly for Intracellular Functions AAIF during 21-24 May 2025 is coming! Register soon at aaif2025-szeged.hu and lets come together in beautiful Szeged for an amazing program covering all aspects of actin biology. #actin, #cytoskeleton
December 18, 2024 at 8:36 AM
The 3rd Actin Assembly for Intracellular Functions AAIF during 21-24 May 2025 is coming! Register soon at aaif2025-szeged.hu and lets come together in beautiful Szeged for an amazing program covering all aspects of actin biology. #actin, #cytoskeleton
Labview over snowy Freiburg
November 24, 2024 at 8:47 AM
Labview over snowy Freiburg
How much I am enjoying this, finally the scientific community is coming back together. Very significant!
November 21, 2024 at 6:32 PM
How much I am enjoying this, finally the scientific community is coming back together. Very significant!
AAIF 3.0 is coming!! save the date!!!
just dm me or @tinatootle.bsky.social for more info
just dm me or @tinatootle.bsky.social for more info
November 14, 2024 at 6:55 PM
AAIF 3.0 is coming!! save the date!!!
just dm me or @tinatootle.bsky.social for more info
just dm me or @tinatootle.bsky.social for more info