gotazu.bsky.social
gotazu.bsky.social
@gotazu.bsky.social
Reposted by gotazu.bsky.social
#eNeuro: Using two mouse models of autism, Sturm et al. highlights how neural activity fluctuations in the olfactory bulb influence behavior in ASD, offering insights into sensory processing mechanisms and potential therapeutic strategies.
https://doi.org/10.1523/ENEURO.0271-25.2025
November 9, 2025 at 6:20 PM
Juvenile male Shank3B het mice have faster learning than WT mice in olfactory task.
www.biorxiv.org/content/10.1...
www.biorxiv.org
February 10, 2025 at 12:03 AM
Reduced number of Thy-1 neurons in three mouse models of ASD in piriform cortex. There was also a lack of exploration of novel odors.
www.biorxiv.org/content/10.1...
www.biorxiv.org
February 4, 2025 at 5:26 PM
Columnar organization in the olfactory bulb revealed using stimulation in slices.
www.biorxiv.org/content/bior...
www.biorxiv.org
February 1, 2025 at 7:38 PM
Olfactory deficits in mouse model of Fragile X. Less exploration of social odors, increase exploration of novel non-social odors. Increased olfactory bulb volume.
www.nature.com/articles/s41...
Altered olfactory responses in Fmr1 KO mice - Scientific Reports
Scientific Reports - Altered olfactory responses in Fmr1 KO mice
www.nature.com
January 27, 2025 at 6:28 PM
Shallow neural response curves proposed as the basis for higher small difference discrimination and more neural response variability in ASD.
www.nature.com/articles/s41...
Autism spectrum disorder variation as a computational trade-off via dynamic range of neuronal population responses - Nature Neuroscience
Individuals with autism spectrum disorder show neural patterns different from those of neurotypical individuals. Here the authors show that this variation reflects a computational trade-off between ac...
www.nature.com
December 26, 2024 at 10:10 PM
Hyperactivity of dopaminergic neurons in substantia nigra in mouse model of fragile X underlies repetitive behaviors.
www.nature.com/articles/s41...
ErbB inhibition rescues nigral dopamine neuron hyperactivity and repetitive behaviors in a mouse model of fragile X syndrome - Molecular Psychiatry
Molecular Psychiatry - ErbB inhibition rescues nigral dopamine neuron hyperactivity and repetitive behaviors in a mouse model of fragile X syndrome
www.nature.com
December 8, 2024 at 2:09 PM