1) stepwise mutation capabilities, but the direction of those is very diverging . So more than the subs rate i am worried about "innate" antigenic evolution capability
2) intra host saltation capability (like Tamiflu resistance mutation) despite very little diffused immuno pressure
1) stepwise mutation capabilities, but the direction of those is very diverging . So more than the subs rate i am worried about "innate" antigenic evolution capability
2) intra host saltation capability (like Tamiflu resistance mutation) despite very little diffused immuno pressure