Geula Hanin
banner
geula.bsky.social
Geula Hanin
@geula.bsky.social
Group Leader @pdncambridge.bsky.social‬ 🔬👩🏻‍🔬🧬🤱
Exploring #Lactation, #ImprintedGenes, #MammaryGlandDevelopment, #Metabolism and #DOHaD
Big shoutout to Boshra Alsulaiti for driving this review! @geneticscam.bsky.social
November 14, 2025 at 12:52 PM
If this sounds like you - send me a DM/email with your CV + transcript + a few lines on your interests. I’d be happy to discuss ideas and support a competitive application.

www.findaphd.com/phds/program...
FindAPhD : PhD Opportunities in the Department of Physiology, Development and Neuroscience at University of Cambridge
Apply for a PhD: PhD Opportunities in the Department of Physiology, Development and Neuroscience at University of Cambridge
www.findaphd.com
November 6, 2025 at 3:04 PM
If you’re excited by lactation biology / mammary gland development / milk composition and want to do mechanistic work in vivo, get in touch.

You’ll need:
• strong academic track record (min good 2:1 or equivalent)
• essential: hands-on molecular biology experience
November 6, 2025 at 3:04 PM
Our atlas is open & ready to explore in this link: geulahanin-mammarygland.shinyapps.io/mammary_data...
Excited to see what the community will do with it!
Mammary ASE Explorer
geulahanin-mammarygland.shinyapps.io
September 10, 2025 at 9:14 AM
Big shoutout to my amazing co-authors 👏 thank you for your ideas and teamwork. A real privilege to work together on this! A special thank you to my mentor Anne Ferguson-Smith, for her guidance and support! @geneticscam.bsky.social
September 10, 2025 at 9:14 AM
Why does it matter?
💡 We identify new targets for lactation failure
💡 Early risk markers for postpartum breast cancer
💡 Insight into how maternal vs paternal genes control lactation
💡 We provide a comprehensive public atlas for the community
September 10, 2025 at 9:14 AM
We also find that postpartum breast cancer–associated genes are activated after weaning in a cell type often overlooked in the mammary gland, revealing early molecular signals specific to postpartum breast cancer.
September 10, 2025 at 9:14 AM
Interestingly, we found that genes linked to lactation problems aren’t confined to milk-producing cells. They’re also active in other mammary cells like mammary adipocytes and stromal cells, broadening our view of what drives successful lactation.
September 10, 2025 at 9:14 AM
Our atlas revealed 25 imprinted genes in the mammary gland, uncovered novel regulators of lactation and showed that genes linked to breastfeeding failure & postpartum breast cancer are active in unexpected cell types.
September 10, 2025 at 9:14 AM
So address this, we built the most detailed mammary dataset yet: 480 transcriptomes, 6 cell types, 10 developmental stages and reciprocal hybrid crosses with 4 biological replicates: A time-lapse map of gene activity across motherhood.
September 10, 2025 at 9:14 AM
Why?
Breastfeeding is vital for both mother & infant, but the genetic & epigenetic regulation of lactation remains poorly understood. Imprinted genes, which exert parent-of-origin-specific effects, drive prenatal growth. We asked if they also shape early nutrition by regulating lactation.
September 10, 2025 at 9:14 AM
We’ll explore topics ranging from public health and global milk banking to molecular biology and lived experiences of breastfeeding.
Alongside thought-provoking talks, there will be plenty of opportunities for discussion, networking and sharing ideas over drinks and light bites.
August 14, 2025 at 3:40 PM