Michele Frison
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frisophagy.bsky.social
Michele Frison
@frisophagy.bsky.social
Postdoc in the lab of Patrick Chinnery at the University of Cambridge. Lover of mitophagy and quality control. Fervid European. Obsessive environmentalist. Yoga enthusiast. Way too excited. Curator of mitophagy newsletter - https://biomed.news/bims-tofagi
Not gonna lie, it does kind of feel like that
November 28, 2025 at 8:55 AM
Really nice and clear summary :)
November 22, 2025 at 3:29 PM
Reposted by Michele Frison
Here's the link to the system, try it! qedscience.com
@qedscience.bsky.social
q.e.d Science
Critical Thinking AI for constructive criticism and science evaluation
qedscience.com
October 15, 2025 at 12:22 PM
Thank you so much 🥹 🗑️🪫❤️🥚
October 12, 2025 at 9:42 AM
Thank you so much Cory! Keeping a look out for more great science from your side
October 11, 2025 at 2:18 PM
Thank you so much Alessandro! Hopefully see you again sometime soon!
October 10, 2025 at 2:22 PM
Thank you Alex, for your help throughout this project and your ubiquitin and mitophagy wisdom! I was really luck to end up working in the same institute as your lab
October 10, 2025 at 2:19 PM
Thank you so much Elias!! The situation in vivo is quite complex, but there's evidence for a role of receptor-mediated mitophagy in germline purifying selection. We still don't know though, if it's two parts of the same mechanisms, or two consecutive QC phenomena

journals.plos.org/plosgenetics...
A role for BCL2L13 and autophagy in germline purifying selection of mtDNA
Author summary We have addressed the role of autophagy on purifying selection of mtDNA by mating different autophagy-deficient mouse models, including knockouts of Parkin, Bcl2l13, Ulk1, and Ulk2, to ...
journals.plos.org
October 10, 2025 at 2:17 PM
Thank you so much Viktor :) Thank god you published your paper on NAD+, autophagy and cell death! The choice of galactose in Figure 4 is all thanks to your lab!! And seeing that the survival experiments followed what you observed was such an important sanity check
October 10, 2025 at 10:58 AM
Thank youuu 😍😍 This would have been nothing without your Western blotting teachings
October 10, 2025 at 10:01 AM