Freya Allen
@freyaallen.bsky.social
PhD student at the University of Birmingham | AMR, evolution and enterococci
Reposted by Freya Allen
Delighted that our review on resistance to last-resort antibiotics in Enterococci has been published in FEMS Microbiology Reviews
academic.oup.com/femsre/advan... (accepted manuscript version)
TL;DR: the Enterococci are really good at evolving resistance to antibiotics in new and creative ways.
academic.oup.com/femsre/advan... (accepted manuscript version)
TL;DR: the Enterococci are really good at evolving resistance to antibiotics in new and creative ways.
Resistance to last-resort antibiotics in enterococci
Abstract. The genus Enterococcus comprises a diverse group of species, many of which are commensal members of the gut microbiota of humans and animals. The
academic.oup.com
November 8, 2025 at 5:41 PM
Delighted that our review on resistance to last-resort antibiotics in Enterococci has been published in FEMS Microbiology Reviews
academic.oup.com/femsre/advan... (accepted manuscript version)
TL;DR: the Enterococci are really good at evolving resistance to antibiotics in new and creative ways.
academic.oup.com/femsre/advan... (accepted manuscript version)
TL;DR: the Enterococci are really good at evolving resistance to antibiotics in new and creative ways.
Reposted by Freya Allen
Absolutely delighted (and proud) that @freyaallen.bsky.social passed her viva with minor corrections today.
Thanks very much @jessicamablair.bsky.social @robfagan.bsky.social for examining!
Thanks very much @jessicamablair.bsky.social @robfagan.bsky.social for examining!
November 6, 2025 at 10:09 PM
Absolutely delighted (and proud) that @freyaallen.bsky.social passed her viva with minor corrections today.
Thanks very much @jessicamablair.bsky.social @robfagan.bsky.social for examining!
Thanks very much @jessicamablair.bsky.social @robfagan.bsky.social for examining!
Reposted by Freya Allen
🚨New pre-print 🚨
We introduce our new tool GOLD-GWAS and demonstrate its use by digging into the evolution of MRSA facilitated by SCCmec
This work was led by talented PhD student @seungwonko.bsky.social who did most of the computational heavylifting 1/n
www.biorxiv.org/content/10.1...
We introduce our new tool GOLD-GWAS and demonstrate its use by digging into the evolution of MRSA facilitated by SCCmec
This work was led by talented PhD student @seungwonko.bsky.social who did most of the computational heavylifting 1/n
www.biorxiv.org/content/10.1...
Genome co-adaptation and the evolution of methicillin resistant Staphylococcus aureus (MRSA)
Background: Antimicrobial resistance (AMR) in bacterial pathogens is a major threat to global health, rendering standard treatments ineffective and increasing the risk of severe infection or death. Re...
www.biorxiv.org
July 23, 2025 at 10:50 AM
🚨New pre-print 🚨
We introduce our new tool GOLD-GWAS and demonstrate its use by digging into the evolution of MRSA facilitated by SCCmec
This work was led by talented PhD student @seungwonko.bsky.social who did most of the computational heavylifting 1/n
www.biorxiv.org/content/10.1...
We introduce our new tool GOLD-GWAS and demonstrate its use by digging into the evolution of MRSA facilitated by SCCmec
This work was led by talented PhD student @seungwonko.bsky.social who did most of the computational heavylifting 1/n
www.biorxiv.org/content/10.1...
Reposted by Freya Allen
🚨 New preprint klaxon 🚨
We characterised the structure of a PNGaseA superfamily member from Bifidobacterium bifidum LMG13195 and highlight its preference for N-glycan structures attached to a peptide, rather than to a native or denatured protein 💫 @imibirmingham.bsky.social
We characterised the structure of a PNGaseA superfamily member from Bifidobacterium bifidum LMG13195 and highlight its preference for N-glycan structures attached to a peptide, rather than to a native or denatured protein 💫 @imibirmingham.bsky.social
PNGaseA-mediated N-glycan stripping from peptides by infant-derived Bifidobacterium bifidum
N-glycans are highly common sources of nutrition for human colonic-dwelling bacteria. These microbes have evolved a several methods to remove N-glycans from proteins; herein we describe the biochemica...
www.biorxiv.org
July 18, 2025 at 11:22 AM
🚨 New preprint klaxon 🚨
We characterised the structure of a PNGaseA superfamily member from Bifidobacterium bifidum LMG13195 and highlight its preference for N-glycan structures attached to a peptide, rather than to a native or denatured protein 💫 @imibirmingham.bsky.social
We characterised the structure of a PNGaseA superfamily member from Bifidobacterium bifidum LMG13195 and highlight its preference for N-glycan structures attached to a peptide, rather than to a native or denatured protein 💫 @imibirmingham.bsky.social
Reposted by Freya Allen
New manuscript from the group
'IS1216 drives the evolution of pRUM-like multidrug resistance plasmids in Enterococcus faecium'
www.biorxiv.org/content/10.1...
/1
'IS1216 drives the evolution of pRUM-like multidrug resistance plasmids in Enterococcus faecium'
www.biorxiv.org/content/10.1...
/1
IS1216 drives the evolution of pRUM-like multidrug resistance plasmids in Enterococcus faecium
pRUM-like plasmids are commonly found in multidrug-resistant Enterococcus faecium , but the evolution of these plasmids has not been characterised in detail. When we analysed the genome sequences of t...
www.biorxiv.org
July 17, 2025 at 8:39 AM
New manuscript from the group
'IS1216 drives the evolution of pRUM-like multidrug resistance plasmids in Enterococcus faecium'
www.biorxiv.org/content/10.1...
/1
'IS1216 drives the evolution of pRUM-like multidrug resistance plasmids in Enterococcus faecium'
www.biorxiv.org/content/10.1...
/1