Very excited to be attending #IWAI2025 in Montreal🍁 organised by David Benrimoh!! already heard some great talks by @rssmith.bsky.social and team 🧠💡

If you’re in #Munich 🥨 and curious about decision-making, perception, and cognition through a translational lens, join us for a seminar I’m hosting on Oct 30 with three fantastic speakers: @jkesby.bsky.social (visiting from 🇦🇺), @miguelbengala.bsky.social, and @jacob-lab.bsky.social 🧠💡

Thrilled to share that @cognemo.bsky.social and I are guest editors for a Schizophrenia Bulletin special issue on Computational markers of psychosis: From latent states to neurobiological mechanisms 🧠✨
If you’re working on this topic, we’d love to see your work!
academic.oup.com/schizophreni...

I very much enjoyed our symposium on discussing a mechanistic understanding of psychotic symptoms with Marta Garrido, @drrickadams.bsky.social and Al Powers at #CPConf2025. Thanks, Marta, for bringing us together!🧠🤩

2/2 We then replicated the findings in a second sample, and showed that an overweighting of priors was associated with increased anterior cingulate glutamate, providing a neurobiological basis for over-reliance on top-down predictions with increasing schizotypy.

1/2 Using a mechanistic Bayesian Belief Updating model, we show how the prior weight is shifted towards the semantic prior. Importantly, our model was informed by schizotypy, showing that when schizotypy increases by 1 point (on a 74-point scale) the prior weight increases by 3.5%!

Looking for a few kind folks to spare 5 precious min & help pilot a "gamified" BEAST task🦓 a task on social information use (Molleman et al 2019)🧠 Just need a quick run to fine-tune it! studies.franziskaknolle.com/publix/h60M3...

Built by our brilliant students Zach Tefertiller & Peter Yi Shan.🎉

Finally out 🎉 - Our new paper explores the neuroimaging and computational differences of reward anticipation in kids with and without psychotic-like experiences. Well done, Pritha Sen, for the great work!!🤩
www.sciencedirect.com/science/arti...

Today in Munich 250000 people demonstrated against the Afd, intolerance, discrimination, racism, etc, my kids and I were 5 of them. It felt good and hopeful! 🌈💪

I am very excited to share our new preprint together with @Isabella Goodwin, @Kelly Diederen, @Emily Hird,
@veithweilnhammer.bsky.social, and @Marta Garrido! Where does predictive processing stand in psychosis research - revisiting Sterzer et al (2018) seven years later. 🧠🔍?
osf.io/preprints/ps...

Study 1 (n=109) found that higher schizotypy was linked to greater reliance on prior beliefs over sensory evidence—a pattern suggesting an overweighting of prior beliefs in people at higher risk for psychosis which also manifested in a higher frequency of false percepts in our task.

In our predictive language task, we manipulated sentence predictability, sensory clarity, and surprise. Using a Bayesian belief updating model, we estimated the “prior weights” in how individuals integrated their expectations vs. the sensory data.