Thé Mercury effect

Cool!

Gene annotations matter for downstream analyses: different structural gene-annotation pipelines yield markedly different orthology calls. We compare four strategies across species and argue for standards & QC before inference. Work led by @silviaprietob.bsky.social. Paper: doi.org/10.1093/bioi...

Congrats, even ALGs in it 😝!

bucolique!

Congrats!

Thanks to all those involved and particularly to Tachiro Goto who promoted this species as a chaetognath model! Please also check also the great News & Views by Lewin & Luo www.nature.com/articles/d41... /6

Finally, the enigmatic MedPost gene finds its place right where it belongs (between Meds and Posts) in an extended Hox cluster of >15 genes /5

We finally identified reversion to ancestral methylation patterns targeting mobile elements whose role in stabilising highly expressed genes was likely taken over by trans-splicing (hereby suggesting a possible role for this puzzling process) /4

We also confirmed the presence of spiralian ALG-fusions in chaetognaths despite fairly rearranged chromosomal architecture, as well as centromeres functioning without the classical CenH3 gene /3

We found that chaetognath genome is as puzzling as their body plan with extensive shuffling of gene repertoire, lots of gene novelty and loss, without evidence of WGD, which appear to be involved in the making of lineage-specific cell types /2

Congrats!