Fabienne Benz
@fabbenz.bsky.social
Working on the spread of antibiotic-resistance plasmids and the role of plasmid-encoded CRISPR-Cas currently postdoc @institut pasteur previously phd @ ETH
4/6 – The big hurdles
🛡️ Bacterial defences — restriction–modification systems, anti-CRISPRs and mutational escape — and how to bypass them
🛡️ Bacterial defences — restriction–modification systems, anti-CRISPRs and mutational escape — and how to bypass them
May 15, 2025 at 6:53 AM
4/6 – The big hurdles
🛡️ Bacterial defences — restriction–modification systems, anti-CRISPRs and mutational escape — and how to bypass them
🛡️ Bacterial defences — restriction–modification systems, anti-CRISPRs and mutational escape — and how to bypass them
3/6 – In-situ delivery
🚚 Engineered phages, conjugative plasmids & more — pros, cons, host range, cargo size and manufacturability. No one-size-fits-all!
🚚 Engineered phages, conjugative plasmids & more — pros, cons, host range, cargo size and manufacturability. No one-size-fits-all!
May 15, 2025 at 6:53 AM
3/6 – In-situ delivery
🚚 Engineered phages, conjugative plasmids & more — pros, cons, host range, cargo size and manufacturability. No one-size-fits-all!
🚚 Engineered phages, conjugative plasmids & more — pros, cons, host range, cargo size and manufacturability. No one-size-fits-all!
2/6 – CRISPR-Cas strategies
🧰 Toolbox & design considerations to eliminate bacteria or their plasmids — and to engineer microbes in situ
🧰 Toolbox & design considerations to eliminate bacteria or their plasmids — and to engineer microbes in situ
May 15, 2025 at 6:53 AM
2/6 – CRISPR-Cas strategies
🧰 Toolbox & design considerations to eliminate bacteria or their plasmids — and to engineer microbes in situ
🧰 Toolbox & design considerations to eliminate bacteria or their plasmids — and to engineer microbes in situ
The honor of being a 'Pasteurian' does not pay rent, certainly not in Paris…
Fingers crossed for today's negotiations with @pasteur.fr
Fingers crossed for today's negotiations with @pasteur.fr
December 17, 2024 at 9:39 AM
The honor of being a 'Pasteurian' does not pay rent, certainly not in Paris…
Fingers crossed for today's negotiations with @pasteur.fr
Fingers crossed for today's negotiations with @pasteur.fr