Ewan Birney
@ewanbirney.bsky.social
Executive Director EMBL. I have an insatiable love of biology. Consultant to ONT and Cantata (Dovetail)
Yup - autocorrect doing its wonders
November 15, 2025 at 7:48 AM
Yup - autocorrect doing its wonders
Too true. A document orientated database before its time. With utterly incomprehensible French error states. Merde!
November 14, 2025 at 10:53 PM
Too true. A document orientated database before its time. With utterly incomprehensible French error states. Merde!
Such a pleasure seeing you recognised like this
November 14, 2025 at 1:54 PM
Such a pleasure seeing you recognised like this
… I was lucky enough to be supervised by him in 1990s in my PhD and collaborated with him ever since
November 14, 2025 at 1:39 PM
… I was lucky enough to be supervised by him in 1990s in my PhD and collaborated with him ever since
Congratulations Zam!
November 14, 2025 at 1:31 PM
Congratulations Zam!
The audience filled up and it was great to talk to a wide range of undergraduates. Excellent questions, as one would expect!
November 12, 2025 at 9:47 AM
The audience filled up and it was great to talk to a wide range of undergraduates. Excellent questions, as one would expect!
And, its direct targets have been well studied (here is one paper amongst many: elifesciences.org/articles/71533). do we understand any part of biology in utter mechanistic detail - not really (not sure the best systems; perhaps some catalytic mechanisms) -definitely not maintenance of pluripotency
Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells
Time-resolved multiomics analysis during Oct4 depletion and recovery reveals concentration-dependent activities of Oct4 in controlling enhancer transcription and chromatin accessibility in mouse embry...
elifesciences.org
November 11, 2025 at 5:14 PM
And, its direct targets have been well studied (here is one paper amongst many: elifesciences.org/articles/71533). do we understand any part of biology in utter mechanistic detail - not really (not sure the best systems; perhaps some catalytic mechanisms) -definitely not maintenance of pluripotency
That's definitely a bad rendering (i don't know where it is from). It looks like a pretty sane DNA binding protein from the (quite a few) protein structures out there. I wouldn't take Wikipedia's choice of protein structure as the best choice (UniProt a far better aggregation point)
November 11, 2025 at 5:11 PM
That's definitely a bad rendering (i don't know where it is from). It looks like a pretty sane DNA binding protein from the (quite a few) protein structures out there. I wouldn't take Wikipedia's choice of protein structure as the best choice (UniProt a far better aggregation point)
This would make me watch it!
November 8, 2025 at 9:10 PM
This would make me watch it!
Reposted by Ewan Birney
Our CEO Prof Sir Rory Collins was speaking at an event at the Labour Party Conference with @zoegrunewald.bsky.social, Andrew McCracken, Nadeem Sarwar & @joshfg.bsky.social MP, a member of the Health and Social Care Committee.
🗞️ Read here: www.newstatesman.com/spotlight/he... by Phin Foster
🗞️ Read here: www.newstatesman.com/spotlight/he... by Phin Foster
Joining the dots through predictive prevention
Predictive prevention could transform healthcare – but only if data, trust and policy align
www.newstatesman.com
November 7, 2025 at 12:12 PM
Our CEO Prof Sir Rory Collins was speaking at an event at the Labour Party Conference with @zoegrunewald.bsky.social, Andrew McCracken, Nadeem Sarwar & @joshfg.bsky.social MP, a member of the Health and Social Care Committee.
🗞️ Read here: www.newstatesman.com/spotlight/he... by Phin Foster
🗞️ Read here: www.newstatesman.com/spotlight/he... by Phin Foster