Thanks, Khaled! We don't know how it works. 🙈 Junctions would be one possibility.

Applause to Victoria Klimenko and huge thanks to @sander1507.bsky.social and the whole HHU Center for Structural Studies team for an amazing collaboration!🥳🥳🥳 (2/2)

In Angomonas, the host and endosymbiont divide in sync. We discovered that ETP2 helps recruit the dynamin-like protein ETP9 to the symbiont division site, revealing a new piece of the host-encoded machinery controlling endosymbiont division.
Beautiful artwork by @anaymaurya.bsky.social 2/2

By sidestepping the complexities of polycistronic transcription (typical for trypanosomatids like Angomonas) Lena’s new system lays the groundwork for a long-awaited conditional expression platform which will be a game changer for dissecting host-symbiont molecular interactions in real time.

Fantastic news! Congrats!!!🎉

If interested in developing a proposal around microbial endosymbionts in protists (Paulinella, Angomonas or other systems), contact me by PM or email. (2/2)

Thank you!😊

Send your 'friend' over! I'll be happy to discuss!😆

The host-encoded dynamin-like protein ETP9 forms a contractile ring around the endosymbiont. ETP9 knock down results in division-impaired, filamentous endosymbionts before cells eventually die. 2/2