It was a pleasure to present our findings at the Ernst Strungmann Institute in Frankfurt last week - on the psychedelic effects that breathwork can induce 🧠

A genuine joy to speak amongst heavyweights in the field of the neuroscience of altered states of consciousness!

Unfortunately I can't make it, but there in academic spirit at @assc28.bsky.social.

If you're there, do check out our poster on the dose-dependent neurophenomenology of the psychedelic DMT 👇

@trisbek.bsky.social will be there to answer any q's 🧠
P165 Tuesday @12:30-13:30

Yesterday I submitted my PhD thesis! 🥂

I'm now awaiting on the viva (17th June) to finalise everything, but am looking for job opportunities following this. If you could share this post far and wide, I'd really appreciate it.

Below is a (very) brief about me.

I'm doing a talk for @aliusresearch.org about our recent study on the dose-dependent effects of DMT on the brain and the mind🧠

Tomorrow!
10:00am Eastern/NY
15:00pm GMT/London
16:00pm CET/Berlin

RSVP here: rb.gy/630099

Briefly, we found that alpha power and permutation entropy were most strongly associated with phenomenology, highlighting how these markers may be the most useful in future neurophenomenological studies on psychedelics [14/20]

Next, we analysed a range of neural features on the EEG data, taking a more agnostic approach to analysing the neural effects (however, we do state our hypotheses and motivations in the paper).

Broadly, we looked at complexity/entropy, connectivity, and spectral measures [12/20]

However, taking time into account, we found some nuanced dose-dependent differences:

The 40mg dose induced more emotionally intense and salient experiences, with more complex and elementary eyes-closed visual imagery, showing that participants are "breaking through" [10/20]

So, what did we find?

Well, first we found that a "Likert Scale" statistical approach did not yield many significant differences in experiences induced between doses [9/20]

To rectify this, we used Temporal Experience Tracing (TET) and EEG (🧠) to measure experiences generated from a medium dose (20mg) and high dose (40mg) of DMT in a repeated-measures counterbalanced design (19 participants x 2 sessions each) [7/20]

However, like any other psychedelic, experiences of DMT aren't constant over time - they undulate with the pharmacodynamics of the substance [5/20]