Eleonora Pali
@elepali.bsky.social
Postdoc at University of Pavia.
Interested in cerebellar synaptic transmission and plasticity in health and disease.
#cerebellum #neurophysiology #patchclamp #STDP
Interested in cerebellar synaptic transmission and plasticity in health and disease.
#cerebellum #neurophysiology #patchclamp #STDP
Pinned
Eleonora Pali
@elepali.bsky.social
· May 13
Coincidence detection between apical and basal dendrites drives STDP in cerebellar Golgi cells
Communications Biology - Cerebellar mf-GoC synapses show anti-symmetric STDP, driven by action potential timing, NMDA receptor activation, and Ca²⁺ dynamics, with inhibitory input...
rdcu.be
Excited to share my PhD work on spike-timing dependent plasticity in cerebellar Golgi cells, just published with @springernature.com in @commsbio.nature.com.
Read here: rdcu.be/elN6L
Read here: rdcu.be/elN6L
Reposted by Eleonora Pali
One of the most beautiful things in the world❤️ #patchclamp #EIRatio
October 17, 2025 at 5:14 PM
One of the most beautiful things in the world❤️ #patchclamp #EIRatio
Reposted by Eleonora Pali
🧠 Opportunity for a post-doctoral position on human neurobiology, funded by the @erc.europa.eu!
🧫You want to use human pluripotent stem cell based models to understand the evolution of human cerebellar neurons and disorders, this position is for you!
🔗Apply here: emploi.cnrs.fr/Offres/CDD/U...
🧫You want to use human pluripotent stem cell based models to understand the evolution of human cerebellar neurons and disorders, this position is for you!
🔗Apply here: emploi.cnrs.fr/Offres/CDD/U...
Portail Emploi CNRS - Offre d'emploi - Postdoctoral researcher in human neurobiology (M/F)
emploi.cnrs.fr
July 30, 2025 at 8:26 AM
🧠 Opportunity for a post-doctoral position on human neurobiology, funded by the @erc.europa.eu!
🧫You want to use human pluripotent stem cell based models to understand the evolution of human cerebellar neurons and disorders, this position is for you!
🔗Apply here: emploi.cnrs.fr/Offres/CDD/U...
🧫You want to use human pluripotent stem cell based models to understand the evolution of human cerebellar neurons and disorders, this position is for you!
🔗Apply here: emploi.cnrs.fr/Offres/CDD/U...
Had such wonderful days in Oslo for #FRM2025. It was a well-organized and truly inspiring conference! Thanks to everyone who stopped by my poster on the role of #cerebellar Purkinje cells in a mouse model of #autism, I really appreciated all your comments and feedback!
June 21, 2025 at 4:12 PM
Had such wonderful days in Oslo for #FRM2025. It was a well-organized and truly inspiring conference! Thanks to everyone who stopped by my poster on the role of #cerebellar Purkinje cells in a mouse model of #autism, I really appreciated all your comments and feedback!
Reposted by Eleonora Pali
A very nice Insight article in eLife by Ikuko Smith on our forthcoming eLife paper on non-ionotropic presynaptic NMDA receptor signalling in spike-timing-dependent long-term depression. elifesciences.org/articles/107...
Synaptic Plasticity: A new mode of action for unconventional NMDA receptors
Presynaptic NMDA receptors can shape timing-dependent long-term depression in a way that departs from their classic postsynaptic role.
elifesciences.org
May 24, 2025 at 7:10 PM
A very nice Insight article in eLife by Ikuko Smith on our forthcoming eLife paper on non-ionotropic presynaptic NMDA receptor signalling in spike-timing-dependent long-term depression. elifesciences.org/articles/107...
Reposted by Eleonora Pali
New preprint alert 📣
#Cerebellum, organoid, autism & brain evolution 🧪 🧫🧠🧬
Collaboration with G. Testa; fruit of years of work by smart students, led by postdoc Davide Aprile. Organoids to understand better the developmental basis of autism (focus: CHD8) & sapiens brain evolution (focus: CADPS2) 🧵
#Cerebellum, organoid, autism & brain evolution 🧪 🧫🧠🧬
Collaboration with G. Testa; fruit of years of work by smart students, led by postdoc Davide Aprile. Organoids to understand better the developmental basis of autism (focus: CHD8) & sapiens brain evolution (focus: CADPS2) 🧵
Benchmarking cerebellar organoids to model autism spectrum disorder and human brain evolution
While cortical organoids have been used to model different facets of neurodevelopmental conditions and human brain evolution, cerebellar organoids have not yet featured so prominently in the same cont...
www.biorxiv.org
May 16, 2025 at 11:08 AM
New preprint alert 📣
#Cerebellum, organoid, autism & brain evolution 🧪 🧫🧠🧬
Collaboration with G. Testa; fruit of years of work by smart students, led by postdoc Davide Aprile. Organoids to understand better the developmental basis of autism (focus: CHD8) & sapiens brain evolution (focus: CADPS2) 🧵
#Cerebellum, organoid, autism & brain evolution 🧪 🧫🧠🧬
Collaboration with G. Testa; fruit of years of work by smart students, led by postdoc Davide Aprile. Organoids to understand better the developmental basis of autism (focus: CHD8) & sapiens brain evolution (focus: CADPS2) 🧵
Reposted by Eleonora Pali
Cerebellar mf-GoC synapses show anti-symmetric STDP, driven by action potential timing, NMDA receptor activation, and Ca²⁺ dynamics, with inhibitory input capable of reversing the plasticity rules. @elepali.bsky.social
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Coincidence detection between apical and basal dendrites drives STDP in cerebellar Golgi cells - Communications Biology
Cerebellar mf-GoC synapses show anti-symmetric STDP, driven by action potential timing, NMDA receptor activation, and Ca²⁺ dynamics, with inhibitory input capable of reversing the plasticity rules.
www.nature.com
May 15, 2025 at 6:23 PM
Cerebellar mf-GoC synapses show anti-symmetric STDP, driven by action potential timing, NMDA receptor activation, and Ca²⁺ dynamics, with inhibitory input capable of reversing the plasticity rules. @elepali.bsky.social
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Excited to share my PhD work on spike-timing dependent plasticity in cerebellar Golgi cells, just published with @springernature.com in @commsbio.nature.com.
Read here: rdcu.be/elN6L
Read here: rdcu.be/elN6L
Coincidence detection between apical and basal dendrites drives STDP in cerebellar Golgi cells
Communications Biology - Cerebellar mf-GoC synapses show anti-symmetric STDP, driven by action potential timing, NMDA receptor activation, and Ca²⁺ dynamics, with inhibitory input...
rdcu.be
May 13, 2025 at 8:40 AM
Excited to share my PhD work on spike-timing dependent plasticity in cerebellar Golgi cells, just published with @springernature.com in @commsbio.nature.com.
Read here: rdcu.be/elN6L
Read here: rdcu.be/elN6L
Reposted by Eleonora Pali
Made a starter pack for researchers who are actively working on or have an interest in the cerebellum.
DM me to be added or reply to this thread!
🧠🤏🏻
go.bsky.app/7X4ekSH
#neuroscience #neuroskyence #cerebellum #neuroimaging #dbs #fmri
DM me to be added or reply to this thread!
🧠🤏🏻
go.bsky.app/7X4ekSH
#neuroscience #neuroskyence #cerebellum #neuroimaging #dbs #fmri
November 25, 2024 at 9:06 PM
Made a starter pack for researchers who are actively working on or have an interest in the cerebellum.
DM me to be added or reply to this thread!
🧠🤏🏻
go.bsky.app/7X4ekSH
#neuroscience #neuroskyence #cerebellum #neuroimaging #dbs #fmri
DM me to be added or reply to this thread!
🧠🤏🏻
go.bsky.app/7X4ekSH
#neuroscience #neuroskyence #cerebellum #neuroimaging #dbs #fmri
Reposted by Eleonora Pali
A black and white offering for the post-Thanksgiving #FluorescenceFriday.
Cerebellum, because one never forgets one's first love 🤍🖤🐭
#neuroskyence #microscopy
Cerebellum, because one never forgets one's first love 🤍🖤🐭
#neuroskyence #microscopy
November 29, 2024 at 2:11 PM
A black and white offering for the post-Thanksgiving #FluorescenceFriday.
Cerebellum, because one never forgets one's first love 🤍🖤🐭
#neuroskyence #microscopy
Cerebellum, because one never forgets one's first love 🤍🖤🐭
#neuroskyence #microscopy
Reposted by Eleonora Pali
Could not believe such thing did not exist. Let me know if you want to be added (/removed)
go.bsky.app/RuCRCgX
go.bsky.app/RuCRCgX
November 16, 2024 at 2:16 PM
Could not believe such thing did not exist. Let me know if you want to be added (/removed)
go.bsky.app/RuCRCgX
go.bsky.app/RuCRCgX
Reposted by Eleonora Pali
Are you building a patch-clamp setup, and would like a cheap heating system? Have you ever wondered how temperature changes the membrane properties of MSNs? Then you might like our latest paper, out now!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A low-cost perfusion heating system for slice electrophysiology - Scientific Reports
Scientific Reports - A low-cost perfusion heating system for slice electrophysiology
www.nature.com
November 18, 2024 at 7:04 PM
Are you building a patch-clamp setup, and would like a cheap heating system? Have you ever wondered how temperature changes the membrane properties of MSNs? Then you might like our latest paper, out now!
www.nature.com/articles/s41...
www.nature.com/articles/s41...