Eduard Unterauer
@eduardunterauer.bsky.social
Physicist | PhD Student @JungmannLab @MPI_Biochem @LMU_Muenchen
Super-resolution microscopy 🔬🧬 Spatial-omics technology 👨🎨🌈 Neuroscience Applications 🧠
Super-resolution microscopy 🔬🧬 Spatial-omics technology 👨🎨🌈 Neuroscience Applications 🧠
Reposted by Eduard Unterauer
Left-handed DNA with conventional right-handed as probes boosts multiplex labelling
📷 @eduardunterauer.bsky.social @evaschentarra.bsky.social Isabelle Pachmayr & @taishatashrin.bsky.social et al
@lmumuenchen.bsky.social @mpibiochem.bsky.social in @natcomms.nature.com
➡️ bpod.org.uk/archive/2025...
📷 @eduardunterauer.bsky.social @evaschentarra.bsky.social Isabelle Pachmayr & @taishatashrin.bsky.social et al
@lmumuenchen.bsky.social @mpibiochem.bsky.social in @natcomms.nature.com
➡️ bpod.org.uk/archive/2025...
October 7, 2025 at 1:33 PM
Left-handed DNA with conventional right-handed as probes boosts multiplex labelling
📷 @eduardunterauer.bsky.social @evaschentarra.bsky.social Isabelle Pachmayr & @taishatashrin.bsky.social et al
@lmumuenchen.bsky.social @mpibiochem.bsky.social in @natcomms.nature.com
➡️ bpod.org.uk/archive/2025...
📷 @eduardunterauer.bsky.social @evaschentarra.bsky.social Isabelle Pachmayr & @taishatashrin.bsky.social et al
@lmumuenchen.bsky.social @mpibiochem.bsky.social in @natcomms.nature.com
➡️ bpod.org.uk/archive/2025...
Reposted by Eduard Unterauer
Thrilled to announce some big news!
Excited to share that I’ve been awarded a Wellcome Trust Early Career Award to establish my research as a Group Leader in the Glycosciences Program at the Institute of Biology and Experimental Medicine (IBYME) in Buenos Aires, Argentina, beginning in early 2026.
Excited to share that I’ve been awarded a Wellcome Trust Early Career Award to establish my research as a Group Leader in the Glycosciences Program at the Institute of Biology and Experimental Medicine (IBYME) in Buenos Aires, Argentina, beginning in early 2026.
October 6, 2025 at 6:24 AM
Thrilled to announce some big news!
Excited to share that I’ve been awarded a Wellcome Trust Early Career Award to establish my research as a Group Leader in the Glycosciences Program at the Institute of Biology and Experimental Medicine (IBYME) in Buenos Aires, Argentina, beginning in early 2026.
Excited to share that I’ve been awarded a Wellcome Trust Early Career Award to establish my research as a Group Leader in the Glycosciences Program at the Institute of Biology and Experimental Medicine (IBYME) in Buenos Aires, Argentina, beginning in early 2026.
Reposted by Eduard Unterauer
Mirror, mirror on the wall... 🪞 I'm super proud to have contributed to our latest work on left-handed DNA-PAINT! Here we introduce 6 new sequences using the left-handed enantiomers of our speed-optimized DNA-PAINT palette, enabling out-of-the-box 12-plex imaging without extra hybridization steps. 🌈🔬
Highly efficient 12-color multiplexing with speed-optimized DNA-PAINT. We are excited to share our latest paper in @natcomms.nature.com, using left-handed DNA to extend speed-optimized DNA-PAINT to 12 targets in a simple and straightforward way! 🧬👈🚀https://www.nature.com/articles/s41467-025-64228-x
October 2, 2025 at 11:58 AM
Mirror, mirror on the wall... 🪞 I'm super proud to have contributed to our latest work on left-handed DNA-PAINT! Here we introduce 6 new sequences using the left-handed enantiomers of our speed-optimized DNA-PAINT palette, enabling out-of-the-box 12-plex imaging without extra hybridization steps. 🌈🔬
Grateful to be part of this work 😊. We are bringing single protein resolved super-resolution microscopy closer to the investigation of systems biological questions 🎨🪄🌈. Congratulations to all authors 🥳
Highly efficient 12-color multiplexing with speed-optimized DNA-PAINT. We are excited to share our latest paper in @natcomms.nature.com, using left-handed DNA to extend speed-optimized DNA-PAINT to 12 targets in a simple and straightforward way! 🧬👈🚀https://www.nature.com/articles/s41467-025-64228-x
October 2, 2025 at 1:34 PM
Grateful to be part of this work 😊. We are bringing single protein resolved super-resolution microscopy closer to the investigation of systems biological questions 🎨🪄🌈. Congratulations to all authors 🥳
Reposted by Eduard Unterauer
Next on stage is Eduard Unterauer @eduardunterauer.bsky.social from @jungmannlab.bsky.social reporting spatial proteomics with DNA PAINT #SMLMS2025
August 27, 2025 at 12:17 PM
Next on stage is Eduard Unterauer @eduardunterauer.bsky.social from @jungmannlab.bsky.social reporting spatial proteomics with DNA PAINT #SMLMS2025
Reposted by Eduard Unterauer
Congratulations to everyone involved: @ipachmayr.bsky.social, @lumasullo.bsky.social, @susannereinhardt.bsky.social, Jisoo Kwon, Ondřej Skořepa, Maite Llop, Sylvia Herter, Marina Bacac and Christian Klein. (6/6)
Read the full story here: www.nature.com/articles/s41...
Read the full story here: www.nature.com/articles/s41...
Resolving the structural basis of therapeutic antibody function in cancer immunotherapy with RESI - Nature Communications
The nanoscale organization of the antigen-antibody complexes influences the therapeutic action of monoclonal antibodies. Here, the authors present a multi-target 3D RESI imaging assay for the nanomete...
www.nature.com
July 28, 2025 at 8:36 AM
Congratulations to everyone involved: @ipachmayr.bsky.social, @lumasullo.bsky.social, @susannereinhardt.bsky.social, Jisoo Kwon, Ondřej Skořepa, Maite Llop, Sylvia Herter, Marina Bacac and Christian Klein. (6/6)
Read the full story here: www.nature.com/articles/s41...
Read the full story here: www.nature.com/articles/s41...
Reposted by Eduard Unterauer
Spatial and stoichiometric in situ analysis of biomolecular oligomerization at single-protein resolution
We are excited to present our latest work published in @natcomms.nature.com
www.nature.com/articles/s41...
We are excited to present our latest work published in @natcomms.nature.com
www.nature.com/articles/s41...
Spatial and stoichiometric in situ analysis of biomolecular oligomerization at single-protein resolution - Nature Communications
Extracting quantitative information on biomolecular oligomerisation with high resolution remains a significant challenge. Here, the authors propose SPINNA, a framework that compares nearest-neighbour ...
www.nature.com
May 7, 2025 at 2:43 PM
Spatial and stoichiometric in situ analysis of biomolecular oligomerization at single-protein resolution
We are excited to present our latest work published in @natcomms.nature.com
www.nature.com/articles/s41...
We are excited to present our latest work published in @natcomms.nature.com
www.nature.com/articles/s41...
Reposted by Eduard Unterauer
Very excited to present our latest work: SPINNA, an analysis framework and software package for single-protein resolution data! 🖥️🤩
We can directly quantify stoichiometry and oligomerization from super-res (DNA-PAINT, RESI) images!! 🧬🎨
We can directly quantify stoichiometry and oligomerization from super-res (DNA-PAINT, RESI) images!! 🧬🎨
Spatial and stoichiometric in situ analysis of biomolecular oligomerization at single-protein resolution
We are excited to present our latest work published in @natcomms.nature.com
www.nature.com/articles/s41...
We are excited to present our latest work published in @natcomms.nature.com
www.nature.com/articles/s41...
Spatial and stoichiometric in situ analysis of biomolecular oligomerization at single-protein resolution - Nature Communications
Extracting quantitative information on biomolecular oligomerisation with high resolution remains a significant challenge. Here, the authors propose SPINNA, a framework that compares nearest-neighbour ...
www.nature.com
May 7, 2025 at 2:56 PM
Very excited to present our latest work: SPINNA, an analysis framework and software package for single-protein resolution data! 🖥️🤩
We can directly quantify stoichiometry and oligomerization from super-res (DNA-PAINT, RESI) images!! 🧬🎨
We can directly quantify stoichiometry and oligomerization from super-res (DNA-PAINT, RESI) images!! 🧬🎨
Reposted by Eduard Unterauer
Excited for our latest work! We developed nanobinders for the luminal domain of Synaptotagmin 1 (calcium sensor for synaptic vesicles). Thanks among others to @verstrekenlab.bsky.social @opazo.bsky.social @meunierlab.bsky.social @volkerhaucke-lab.bsky.social www.biorxiv.org/content/10.1...
Nanobinders for Synaptotagmin 1 enable the analysis of synaptic vesicle dynamics in rodent and human models.
Synaptic neurotransmission is a critical hallmark of brain activity and one of the first processes to be affected in neural diseases. Monitoring this process, and in particular synaptic vesicle recycl...
www.biorxiv.org
April 22, 2025 at 9:27 AM
Excited for our latest work! We developed nanobinders for the luminal domain of Synaptotagmin 1 (calcium sensor for synaptic vesicles). Thanks among others to @verstrekenlab.bsky.social @opazo.bsky.social @meunierlab.bsky.social @volkerhaucke-lab.bsky.social www.biorxiv.org/content/10.1...
Reposted by Eduard Unterauer
IMAGING LIGAND-RECEPTOR INTERACTIONS AT SINGLE-PROTEIN RESOLUTION WITH DNA-PAINT🔬
Ever wonder how cells "talk"? It starts when ligands bind to receptors on cell surfaces. We have cracked the challenge of imaging small ligands on cell surfaces. #DNAPAINT #celltalk 💬
doi.org/10.1002/smtd...
Ever wonder how cells "talk"? It starts when ligands bind to receptors on cell surfaces. We have cracked the challenge of imaging small ligands on cell surfaces. #DNAPAINT #celltalk 💬
doi.org/10.1002/smtd...
April 10, 2025 at 11:40 AM
IMAGING LIGAND-RECEPTOR INTERACTIONS AT SINGLE-PROTEIN RESOLUTION WITH DNA-PAINT🔬
Ever wonder how cells "talk"? It starts when ligands bind to receptors on cell surfaces. We have cracked the challenge of imaging small ligands on cell surfaces. #DNAPAINT #celltalk 💬
doi.org/10.1002/smtd...
Ever wonder how cells "talk"? It starts when ligands bind to receptors on cell surfaces. We have cracked the challenge of imaging small ligands on cell surfaces. #DNAPAINT #celltalk 💬
doi.org/10.1002/smtd...
Reposted by Eduard Unterauer
One month ago today, I published my first paper with the @jungmannlab.bsky.social 🥳
What better way to celebrate #MicroscopyMonday than with this STAR Protocol on SUM-PAINT spatial proteomic imaging: a guide for highly multiplexed DNA-PAINT imaging in neurons. star-protocols.cell.com/protocols/4066
What better way to celebrate #MicroscopyMonday than with this STAR Protocol on SUM-PAINT spatial proteomic imaging: a guide for highly multiplexed DNA-PAINT imaging in neurons. star-protocols.cell.com/protocols/4066
Cell Press: STAR Protocols
STAR Protocols is an open access, peer-reviewed journal from Cell Press. We offer structured, transparent, accessible, and repeatable step-by-step experimental and computational protocols from all are...
star-protocols.cell.com
April 7, 2025 at 7:58 PM
One month ago today, I published my first paper with the @jungmannlab.bsky.social 🥳
What better way to celebrate #MicroscopyMonday than with this STAR Protocol on SUM-PAINT spatial proteomic imaging: a guide for highly multiplexed DNA-PAINT imaging in neurons. star-protocols.cell.com/protocols/4066
What better way to celebrate #MicroscopyMonday than with this STAR Protocol on SUM-PAINT spatial proteomic imaging: a guide for highly multiplexed DNA-PAINT imaging in neurons. star-protocols.cell.com/protocols/4066
Reposted by Eduard Unterauer
ÅNGSTRÖM-RESOLUTION IMAGING OF CELL-SURFACE GLYCANS 🧬🎨🍬
The glycocalyx, our cells' sugar coat, holds secrets in immunology, cancer, viral infections, and more. Visualizing its molecular architecture was impossible… until now. #glycotime #microscopy
www.biorxiv.org/content/10.1...
The glycocalyx, our cells' sugar coat, holds secrets in immunology, cancer, viral infections, and more. Visualizing its molecular architecture was impossible… until now. #glycotime #microscopy
www.biorxiv.org/content/10.1...
February 10, 2025 at 8:21 AM
ÅNGSTRÖM-RESOLUTION IMAGING OF CELL-SURFACE GLYCANS 🧬🎨🍬
The glycocalyx, our cells' sugar coat, holds secrets in immunology, cancer, viral infections, and more. Visualizing its molecular architecture was impossible… until now. #glycotime #microscopy
www.biorxiv.org/content/10.1...
The glycocalyx, our cells' sugar coat, holds secrets in immunology, cancer, viral infections, and more. Visualizing its molecular architecture was impossible… until now. #glycotime #microscopy
www.biorxiv.org/content/10.1...
At the end of the PhD journey, you realize the goal was actually only part of the deal. It’s the people you get to know along the way and the experiences you share that shape you to become a wiser and happier human being. Thanks for the great time @JungmannLab
January 28, 2025 at 2:16 PM
At the end of the PhD journey, you realize the goal was actually only part of the deal. It’s the people you get to know along the way and the experiences you share that shape you to become a wiser and happier human being. Thanks for the great time @JungmannLab
Very proud to be part of this exciting work 😊. It's a great step forward in enabling highest resolution DNA-PAINT for everyone 🌈
x.com/PhilippSteen/s…
x.com/PhilippSteen/s…
January 28, 2025 at 2:16 PM
Very proud to be part of this exciting work 😊. It's a great step forward in enabling highest resolution DNA-PAINT for everyone 🌈
x.com/PhilippSteen/s…
x.com/PhilippSteen/s…
Ready to present the SUM-PAINT story at the single molecule approaches to biology @GordonConf in beautiful Maine 😊. If you are interested, stop by Wednesday or Thursday 🙂
January 28, 2025 at 2:16 PM
Ready to present the SUM-PAINT story at the single molecule approaches to biology @GordonConf in beautiful Maine 😊. If you are interested, stop by Wednesday or Thursday 🙂
How many synapses can you detect in a single Field of View? The answer is many😊. Here we have a 7plex image with 450 Synapses imaged with SUM-PAINT @Jungmannlab, that I am excited to share with you. Happy #FluorescenceFriday
January 28, 2025 at 2:16 PM
How many synapses can you detect in a single Field of View? The answer is many😊. Here we have a 7plex image with 450 Synapses imaged with SUM-PAINT @Jungmannlab, that I am excited to share with you. Happy #FluorescenceFriday
We wish you a happy #MicroscopyMonday and if you got interested into applying this technology yourself, get in touch with @Jungmannlab 😊
January 28, 2025 at 2:16 PM
We wish you a happy #MicroscopyMonday and if you got interested into applying this technology yourself, get in touch with @Jungmannlab 😊
If you got curious check out the full publication 😊 @JungmannLab @CellCellPress
doi.org/10.1016/j.cell…
doi.org/10.1016/j.cell…
January 28, 2025 at 2:16 PM
If you got curious check out the full publication 😊 @JungmannLab @CellCellPress
doi.org/10.1016/j.cell…
doi.org/10.1016/j.cell…
Very proud to finally see our huge collaborative work published 😊. Once again, congrats to all authors and thanks for sticking with me through all these times 🙈🚀
x.com/JungmannLab/st…
x.com/JungmannLab/st…
January 28, 2025 at 2:16 PM
Very proud to finally see our huge collaborative work published 😊. Once again, congrats to all authors and thanks for sticking with me through all these times 🙈🚀
x.com/JungmannLab/st…
x.com/JungmannLab/st…