Ed Gilbert
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edmundgilbert.bsky.social
Ed Gilbert
@edmundgilbert.bsky.social
Geneticist at RCSI Dublin and general nerd.
Today our collaborators at University of Edinburgh and I are reporting our paper on haemochromatosis risk in Ireland and the UK using the UK Biobank, NHS DigiTrials, and more!
You can read all about it here: rdcu.be/e17s3

And an accessible review from RCSI: www.rcsi.com/dublin/news-...
The landscape of hereditary haemochromatosis risk and diagnosis across the British Isles and Ireland
Nature Communications - Here the authors analyse genetic data for over 400,000 British and Irish people, showing that the frequency of the major genetic risk factor for haemochromatosis varies from...
rdcu.be
February 3, 2026 at 2:09 PM
Reposted by Ed Gilbert
Pleased to share our latest paper in Science Advances on myeloid cell ‘trained hypercoagulability’! 🚀 Project led by @aislingrehill.bsky.social - huge thanks to our collaborators & funders @tcddublin.bsky.social @researchireland.bsky.social CHI and HRB Ireland tinyurl.com/df4fsrrx
Trained immunity causes myeloid cell hypercoagulability
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tinyurl.com
March 7, 2025 at 7:28 PM
Reposted by Ed Gilbert
New publication from our group in @naturecomms.bsky.social led by Gemma Leon @rcsi.bsky.social
Thanks to our collaborators at @tcddublin.bsky.social, CHI Crumlin, and to @researchireland.bsky.social and Children’s Health Ireland for funding. Open access link: rdcu.be/d93ds
Tissue factor-dependent colitogenic CD4+ T cell thrombogenicity is regulated by activated protein C signalling
Nature Communications - Patients with inflammatory bowel disease (IBD) have increased risk for venous thromboembolism, but mechanistic insight is still lacking. Using both mouse experimental...
rdcu.be
February 16, 2025 at 12:50 PM
Delighted to have part of Ashwini's PhD work published in the EJHG! Here Ashwini drills down into our earlier fine-scale structure work to look at the relative signals of isolation across Ireland and Britain

www.nature.com/articles/s41...
[1]
A genetic perspective on the recent demographic history of Ireland and Britain - European Journal of Human Genetics
European Journal of Human Genetics - A genetic perspective on the recent demographic history of Ireland and Britain
www.nature.com
February 5, 2025 at 2:29 PM