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dzne.science
DZNE research center
@dzne.science
1.1K followers 300 following 220 posts
Dedicated to advancing the scientific understanding of neurodegenerative diseases - from mechanisms to diagnosis, therapy, and prevention (such as AD, PD or ALS).

🔗 Imprint: https://dzne.de/en/imprint
🔗 Data Protection: https://dzne.de/en/data-protection/
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dzne.science
DZNE research center @dzne.science · 3d
DZNE is part of the European research initiative ACCESS-AD, receiving ~€1M to improve Alzheimer’s diagnosis and care. The project explores innovative tools like app-based cognitive tests to support earlier and better treatment.

👉 www.dzne.de/en/im-fokus/...
DZNE participating in European Research Initiative on Alzheimer’s
ACCESS-AD aims to advance the use of innovative methods in clinical practice.
www.dzne.de
dzne.science
New paper out: Plasma p ‐tau 217 as a suitable biomarker for monitoring cognitive changes in Alzheimer's disease: Biel, Davina; Steward, Anna; Dewenter, Anna; et al.
Alzheimer's and dementia Vol. 21, no. S2, p. e104771 | Thanks for sharing #dzne #papers
Plasma p ‐tau 217 as a suitable biomarker for monitoring cognitive changes in Alzheimer's disease
Biel, Davina; Steward, Anna; Dewenter, Anna; et al. Alzheimer's and dementia Vol. 21, no. S2, p. e104771
dlvr.it
January 16, 2026 at 6:13 PM
dzne.science
New paper out: Multi‐tracer PET monitoring of an immunomodulatory therapy in 4R tauopathy: Evaluating a novel drug's impact on glial function and protein pathology: Bathe, Tim; Salomasova, Svetlana; Lalia, Manvir; et al.
Alzheimer's and dementia Vol. 21, no. S2,… | Thanks for sharing #dzne #papers
Multi‐tracer PET monitoring of an immunomodulatory therapy in 4R tauopathy: Evaluating a novel drug's impact on glial function and protein pathology
Bathe, Tim; Salomasova, Svetlana; Lalia, Manvir; et al. Alzheimer's and dementia Vol. 21, no. S2, p. e104796
dlvr.it
January 16, 2026 at 1:53 PM
dzne.science
New paper out: Integrating simulated and experimental data to identify mitochondrial bioenergetic defects in Parkinson's Disease models.: Chenna, Sandeep; Joselin, Alvin; Theurey, Pierre; et al.
PLOS ONE Vol. 21, no. 1, p. e0339326 - | Thanks for sharing #dzne #papers
Integrating simulated and experimental data to identify mitochondrial bioenergetic defects in Parkinson's Disease models.
Chenna, Sandeep; Joselin, Alvin; Theurey, Pierre; et al. PLOS ONE Vol. 21, no. 1, p. e0339326 -
dlvr.it
January 16, 2026 at 10:53 AM
dzne.science
New paper out: AI Superresolution: Converting T1‐weighted MRI from 3T to 7T resolution toward enhanced imaging biomarkers for Alzheimer's disease: Gicquel, Malo; Flood, Gabrielle; Zhao, Ruoyi; et al.
Alzheimer's and dementia Vol. 21, no. S2, p. e106600 | Thanks for sharing #dzne #papers
AI Superresolution: Converting T1‐weighted MRI from 3T to 7T resolution toward enhanced imaging biomarkers for Alzheimer's disease
Gicquel, Malo; Flood, Gabrielle; Zhao, Ruoyi; et al. Alzheimer's and dementia Vol. 21, no. S2, p. e106600
dlvr.it
January 15, 2026 at 6:13 PM
dzne.science
New paper out: Nucleus Basalis of Meynert: Functional Connectivity and Morphometry in Alzheimer's Disease and Frontotemporal Dementia: Kindler, Christine; Gillis, Grace; Bhalerao, Gaurav V; et al.
Alzheimer's and dementia Vol. 21, no. S2, p. e105620 | Thanks for sharing #dzne #papers
Nucleus Basalis of Meynert: Functional Connectivity and Morphometry in Alzheimer's Disease and Frontotemporal Dementia
Kindler, Christine; Gillis, Grace; Bhalerao, Gaurav V; et al. Alzheimer's and dementia Vol. 21, no. S2, p. e105620
dlvr.it
January 15, 2026 at 1:53 PM
dzne.science
New paper out: Early changes in basal forebrain volume and cognitive function in preclinical autosomal dominant Alzheimer's disease: He, Bing; Ospina, Paula; Espinosa, Alejandro; et al.
Alzheimer's and dementia Vol. 21, no. S2, p. e105027 | Thanks for sharing #dzne #papers
Early changes in basal forebrain volume and cognitive function in preclinical autosomal dominant Alzheimer's disease
He, Bing; Ospina, Paula; Espinosa, Alejandro; et al. Alzheimer's and dementia Vol. 21, no. S2, p. e105027
dlvr.it
January 15, 2026 at 10:54 AM
Reposted by DZNE research center
institutducerveau.bsky.social
🔬 As part of the World Brain Health Forum 2026, the second session of the day explored emerging perspectives in neuroscience through the insights of early-career researchers.

#WBHF2026
January 14, 2026 at 5:05 PM
Reposted by DZNE research center
institutducerveau.bsky.social
For its 15th anniversary, the Brain Institute is hosting the World Brain Health Forum in Paris on Jan 14–15, 2026. Experts worldwide will discuss brain health challenges and turning science into solutions.

👉 Registration is mandatory. Program & info: https://2026.worldbrainhealthforum.org/en/
December 17, 2025 at 11:55 AM
dzne.science
DZNE is part of the European research initiative ACCESS-AD, receiving ~€1M to improve Alzheimer’s diagnosis and care. The project explores innovative tools like app-based cognitive tests to support earlier and better treatment.

👉 www.dzne.de/en/im-fokus/...
DZNE participating in European Research Initiative on Alzheimer’s
ACCESS-AD aims to advance the use of innovative methods in clinical practice.
www.dzne.de
January 13, 2026 at 11:01 AM
dzne.science
New paper out: Axon initial segment dynamics during associative fear learning: Benoit, Chloé Maëlle; Ganea, Dan Alin; Paricio-Montesinos, Ricardo; et al.
Nature neuroscience  | Thanks for sharing #dzne #papers
Axon initial segment dynamics during associative fear learning
Benoit, Chloé Maëlle; Ganea, Dan Alin; Paricio-Montesinos, Ricardo; et al. Nature neuroscience 
dlvr.it
January 7, 2026 at 10:54 AM
dzne.science
New paper out: Changes in Task‐evoked Pupil Dilation during Emotional Memory as a Marker of Noradrenergic Function in Healthy Aging and MCI: Zhunussova, Alina; Loane, Clare; Kurt, Elif; et al.
Alzheimer's and dementia Vol. 21, no. S7, p. e108410 | Thanks for sharing #dzne #papers
Changes in Task‐evoked Pupil Dilation during Emotional Memory as a Marker of Noradrenergic Function in Healthy Aging and MCI
Zhunussova, Alina; Loane, Clare; Kurt, Elif; et al. Alzheimer's and dementia Vol. 21, no. S7, p. e108410
dlvr.it
January 6, 2026 at 10:54 AM
dzne.science
New paper out: Cognitive training–related volumetric changes in the A36 perirhinal area are associated with mnemonic discrimination gains in older adults: a 7T MRI study: Iliopoulos, Panagiotis; Gellersen, Helena M.; Rong, Boyan; et al.
Alzheimer's and dementia… | Thanks for sharing #dzne #papers
Cognitive training–related volumetric changes in the A36 perirhinal area are associated with mnemonic discrimination gains in older adults: a 7T MRI study
Iliopoulos, Panagiotis; Gellersen, Helena M.; Rong, Boyan; et al. Alzheimer's and dementia Vol. 21, no. S7, p. e108566
dlvr.it
January 5, 2026 at 6:13 PM
dzne.science
New paper out: Anti‐oligomeric PRI‐002 does not cause ARIA‐E in an ongoing Phase 2 trial: Peters, Oliver; Jürgens, Dagmar; Tischler, Gerhard; et al.
Alzheimer's and dementia Vol. 21, no. S7, p. e108724 | Thanks for sharing #dzne #papers
Anti‐oligomeric PRI‐002 does not cause ARIA‐E in an ongoing Phase 2 trial
Peters, Oliver; Jürgens, Dagmar; Tischler, Gerhard; et al. Alzheimer's and dementia Vol. 21, no. S7, p. e108724
dlvr.it
January 5, 2026 at 1:53 PM
dzne.science
New paper out: Long‐Read Sequencing Reveals Ancestral intragenic APOE Haplotypes with Distinct Roles in Alzheimer’s Disease: Ruiz, Agustin; García-González, Pablo; Puerta, Raquel; et al.
Alzheimer's and dementia Vol. 21, no. S7, p. e108005 | Thanks for sharing #dzne #papers
Long‐Read Sequencing Reveals Ancestral intragenic APOE Haplotypes with Distinct Roles in Alzheimer’s Disease
Ruiz, Agustin; García-González, Pablo; Puerta, Raquel; et al. Alzheimer's and dementia Vol. 21, no. S7, p. e108005
dlvr.it
January 5, 2026 at 10:53 AM
Reposted by DZNE research center
fabmusacchio.bsky.social
Happy to share that our #JOSS paper on MotilA is now published 😊

#OpenSource #Python pipeline for reproducible, batch-scale analysis of #microglia fine-process motility in 3D/4D in vivo multiphoton imaging:

📄 doi.org/10.21105/jos...
💻 github.com/FabrizioMusa...

#Neuroscience 🧪 #OpenScience
MotilA – A Python pipeline for the analysis of microglial fine process motility in 3D time-lapse multiphoton microscopy data
Musacchio et al., (2025). MotilA – A Python pipeline for the analysis of microglial fine process motility in 3D time-lapse multiphoton microscopy data. Journal of Open Source Software, 10(116), 9267, ...
doi.org
December 23, 2025 at 6:58 PM
dzne.science
New paper out: Risk of Epilepsy and Factors Associated With Time to Seizure Remission in Anti-LGI1 Encephalitis: Long-Term Outcome in 236 Patients.: Baumgartner, Tobias; Freyberg, Moritz; Campetella, Lucia; et al.
Neurology: Neuroimmunology & Neuroinflammation ;… | Thanks for sharing #dzne #papers
Risk of Epilepsy and Factors Associated With Time to Seizure Remission in Anti-LGI1 Encephalitis: Long-Term Outcome in 236 Patients.
Baumgartner, Tobias; Freyberg, Moritz; Campetella, Lucia; et al. Neurology: Neuroimmunology & Neuroinflammation ; official journal of the American Academy of Neurology Vol. 12, no. 6, p. e200469
dlvr.it
January 4, 2026 at 6:13 PM
dzne.science
New paper out: CSF Biomarkers of Neuroinflammation in Prediction of Brain Atrophy: Özlü, Serap; Grazia, Alice; Dyrba, Martin; et al.
Alzheimer's and dementia Vol. 21, no. S7, p. e108159 | Thanks for sharing #dzne #papers
CSF Biomarkers of Neuroinflammation in Prediction of Brain Atrophy
Özlü, Serap; Grazia, Alice; Dyrba, Martin; et al. Alzheimer's and dementia Vol. 21, no. S7, p. e108159
dlvr.it
January 4, 2026 at 1:54 PM
dzne.science
New paper out: Episodic memory network connectivity with aging and Alzheimer’s disease pathology in cognitively unimpaired older adults: Gatzen, Julia; Fischer, Larissa; Behrenbruch, Niklas; et al.
Alzheimer's and dementia Vol. 21, no. S7, p. e108678 | Thanks for sharing #dzne #papers
Episodic memory network connectivity with aging and Alzheimer’s disease pathology in cognitively unimpaired older adults
Gatzen, Julia; Fischer, Larissa; Behrenbruch, Niklas; et al. Alzheimer's and dementia Vol. 21, no. S7, p. e108678
dlvr.it
January 4, 2026 at 10:53 AM
dzne.science
New paper out: Bridging Immunity and Hemostasis: Technical Foundations of Platelet-Leukocyte Co-cultures.: Secchim Ribeiro, Lucas
  | Thanks for sharing #dzne #papers
Bridging Immunity and Hemostasis: Technical Foundations of Platelet-Leukocyte Co-cultures.
Secchim Ribeiro, Lucas  
dlvr.it
January 3, 2026 at 6:14 PM
dzne.science
New paper out: Direct Inoculation of Pathogenic Yeasts into Mouse Lung by Trans-tracheal Instillation.: Campi Santos, Patricia
  | Thanks for sharing #dzne #papers
Direct Inoculation of Pathogenic Yeasts into Mouse Lung by Trans-tracheal Instillation.
Campi Santos, Patricia  
dlvr.it
January 3, 2026 at 1:53 PM
dzne.science
New paper out: The diagnostic value of transcranial sonography in Swedish parkinsonism patients: A retrospective cohort study with long-term follow-up.: Stiehm, M.; Nilsson, C.; Skogar, Ö; et al.
Clinical parkinsonism & related disorders Vol. 13, p. 100411 - | Thanks for sharing #dzne #papers
The diagnostic value of transcranial sonography in Swedish parkinsonism patients: A retrospective cohort study with long-term follow-up.
Stiehm, M.; Nilsson, C.; Skogar, Ö; et al. Clinical parkinsonism & related disorders Vol. 13, p. 100411 -
dlvr.it
January 3, 2026 at 10:54 AM
dzne.science
New paper out: Hippocampal vascularization is associated with greater efficiency during a remote real world wayfinding training in older adults: Marquardt, Jonas; Vockert, Niklas; Behrenbruch, Niklas; et al.
Alzheimer's and dementia Vol. 21 Suppl 9, no. Suppl 9,… | Thanks for sharing #dzne #papers
Hippocampal vascularization is associated with greater efficiency during a remote real world wayfinding training in older adults
Marquardt, Jonas; Vockert, Niklas; Behrenbruch, Niklas; et al. Alzheimer's and dementia Vol. 21 Suppl 9, no. Suppl 9, p. e110578
dlvr.it
January 2, 2026 at 6:13 PM
dzne.science
New paper out: Remote and unsupervised monitoring of episodic memory decline in patients with prodromal Alzheimer's disease: Polk, Sarah E; Clark, Lindsay R; Basche, Kristin E; et al.
Alzheimer's and dementia Vol. 21 Suppl 9, no. Suppl 9, p. e110650 | Thanks for sharing #dzne #papers
Remote and unsupervised monitoring of episodic memory decline in patients with prodromal Alzheimer's disease
Polk, Sarah E; Clark, Lindsay R; Basche, Kristin E; et al. Alzheimer's and dementia Vol. 21 Suppl 9, no. Suppl 9, p. e110650
dlvr.it
January 2, 2026 at 1:53 PM
dzne.science
New paper out: CSF biomarkers of neuroinflammation are associated with regional atrophy.: Özlü, Serap; Dyrba, Martin; Grazia, Alice; et al.
Journal of neurology Vol. 273, no. 1, p. 46 | Thanks for sharing #dzne #papers
CSF biomarkers of neuroinflammation are associated with regional atrophy.
Özlü, Serap; Dyrba, Martin; Grazia, Alice; et al. Journal of neurology Vol. 273, no. 1, p. 46
dlvr.it
January 2, 2026 at 10:53 AM
dzne.science
New paper out: Nucleus Basalis of Meynert: Functional Connectivity and Morphometry in Alzheimer’s Disease and Frontotemporal Dementia: Kindler, Christine; Gillis, Grace; Bhalerao, Gaurav V; et al.
Alzheimer's and dementia Vol. 21 Suppl 8, no. Suppl 8, p. e110164 | Thanks for sharing #dzne #papers
Nucleus Basalis of Meynert: Functional Connectivity and Morphometry in Alzheimer’s Disease and Frontotemporal Dementia
Kindler, Christine; Gillis, Grace; Bhalerao, Gaurav V; et al. Alzheimer's and dementia Vol. 21 Suppl 8, no. Suppl 8, p. e110164
dlvr.it
January 1, 2026 at 6:14 PM