DZNE research center
@dzne.science
Dedicated to advancing the scientific understanding of neurodegenerative diseases - from mechanisms to diagnosis, therapy, and prevention (such as AD, PD or ALS).
🔗 Imprint: https://dzne.de/en/imprint
🔗 Data Protection: https://dzne.de/en/data-protection/
🔗 Imprint: https://dzne.de/en/imprint
🔗 Data Protection: https://dzne.de/en/data-protection/
🏆 Congrats Lars Lannfelt! The Swedish #Alzheimer’s researcher, who paved the way for the drug #Lecanemab has received the "Hartwig Piepenbrock-DZNE Prize". The award recognizes exceptional research on neurodegenerative diseases.
👉 www.linkedin.com/posts/dzne_d...
👉 www.linkedin.com/posts/dzne_d...
November 20, 2025 at 8:02 PM
🏆 Congrats Lars Lannfelt! The Swedish #Alzheimer’s researcher, who paved the way for the drug #Lecanemab has received the "Hartwig Piepenbrock-DZNE Prize". The award recognizes exceptional research on neurodegenerative diseases.
👉 www.linkedin.com/posts/dzne_d...
👉 www.linkedin.com/posts/dzne_d...
New paper out: Region-specific drivers of CSF mobility measured with MRI in humans.: Hirschler, Lydiane; Runderkamp, Bobby A; Decker, Andreas; et al.
Nature neuroscience Vol. 28, no. 11, p. 2392 - 2401 Thanks for sharing! #dzne #papers
Nature neuroscience Vol. 28, no. 11, p. 2392 - 2401 Thanks for sharing! #dzne #papers
Region-specific drivers of CSF mobility measured with MRI in humans.
Hirschler, Lydiane; Runderkamp, Bobby A; Decker, Andreas; et al.
Nature neuroscience Vol. 28, no. 11, p. 2392 - 2401
dlvr.it
November 19, 2025 at 12:26 PM
New paper out: Amyloid‐β Seeds in Alzheimer's Disease: Research Challenges and Implications: Beschorner, Natalie; Xu, Ying; Jucker, Mathias; et al.
Journal of neurochemistry Vol. 169, no. 11, p. e70267 Thanks for sharing! #dzne #papers
Journal of neurochemistry Vol. 169, no. 11, p. e70267 Thanks for sharing! #dzne #papers
Amyloid‐β Seeds in Alzheimer's Disease: Research Challenges and Implications
Beschorner, Natalie; Xu, Ying; Jucker, Mathias; et al.
Journal of neurochemistry Vol. 169, no. 11, p. e70267
dlvr.it
November 19, 2025 at 12:26 PM
New paper out: Compound Muscle Action Potential (CMAP) Amplitude Trajectories and Pattern in Adults with 5q-Spinal Muscular Atrophy Receiving Nusinersen Therapy: A Multicenter, Binational Observational Study.: Bjelica, Bogdan; Wohnrade, Camilla; Osmanovic, Alma; et… Thanks for sharing! #dzne #papers
Compound Muscle Action Potential (CMAP) Amplitude Trajectories and Pattern in Adults with 5q-Spinal Muscular Atrophy Receiving Nusinersen Therapy: A Multicenter, Binational Observational Study.
Bjelica, Bogdan; Wohnrade, Camilla; Osmanovic, Alma; et al.
European journal of neurology Vol. 32, no. 11, p. e70405
dlvr.it
November 19, 2025 at 12:26 PM
New paper out: Compound Muscle Action Potential (CMAP) Amplitude Trajectories and Pattern in Adults with 5q-Spinal Muscular Atrophy Receiving Nusinersen Therapy: A Multicenter, Binational Observational Study.: Bjelica, Bogdan; Wohnrade, Camilla; Osmanovic, Alma; et… Thanks for sharing! #dzne #papers
New paper out: Cognitive performance in patients with ischemic stroke and additional myocardial injury - results from the multicenter prospective observational PRAISE study.: von Rennenberg, Regina; Litmeier, Simon; Szabo, Kristina; et al.
Neurological research and… Thanks for sharing! #dzne #papers
Neurological research and… Thanks for sharing! #dzne #papers
Cognitive performance in patients with ischemic stroke and additional myocardial injury - results from the multicenter prospective observational PRAISE study.
von Rennenberg, Regina; Litmeier, Simon; Szabo, Kristina; et al.
Neurological research and practice Vol. 7, no. 1, p. 84
dlvr.it
November 18, 2025 at 12:28 PM
New paper out: VGF AQEE- and GGEE-peptides differentiate between dementia types.: Noli, B.; Muqaku, B.; Gouda, M.; et al.
Journal of neurology Vol. 272, no. 11, p. 745 Thanks for sharing! #dzne #papers
Journal of neurology Vol. 272, no. 11, p. 745 Thanks for sharing! #dzne #papers
VGF AQEE- and GGEE-peptides differentiate between dementia types.
Noli, B.; Muqaku, B.; Gouda, M.; et al.
Journal of neurology Vol. 272, no. 11, p. 745
dlvr.it
November 18, 2025 at 12:28 PM
New paper out: Modeling Alzheimer's disease: Bayesian copula graphical model from demographic, cognitive, and neuroimaging data.: Vogels, Lucas; Mohammadi, Reza; Schoonhoven, Marit; et al.
Journal of Alzheimer's disease Vol. 108, no. 1_suppl Thanks for sharing! #dzne #papers
Journal of Alzheimer's disease Vol. 108, no. 1_suppl Thanks for sharing! #dzne #papers
Modeling Alzheimer's disease: Bayesian copula graphical model from demographic, cognitive, and neuroimaging data.
Vogels, Lucas; Mohammadi, Reza; Schoonhoven, Marit; et al.
Journal of Alzheimer's disease Vol. 108, no. 1_suppl
dlvr.it
November 17, 2025 at 12:32 PM
New paper out: A computational ontology framework for the synthesis of multi-level pathology reports from brain MRI scans.: Singh, Devesh; Grazia, Alice; Reiz, Achim; et al.
Journal of Alzheimer's disease Vol. 108, no. 1_suppl Thanks for sharing! #dzne #papers
Journal of Alzheimer's disease Vol. 108, no. 1_suppl Thanks for sharing! #dzne #papers
A computational ontology framework for the synthesis of multi-level pathology reports from brain MRI scans.
Singh, Devesh; Grazia, Alice; Reiz, Achim; et al.
Journal of Alzheimer's disease Vol. 108, no. 1_suppl
dlvr.it
November 17, 2025 at 12:32 PM
New paper out: How can Alzheimer's disease blood-based biomarkers reach clinical practice?: Perneczky, Robert; Quevenco, Frances-Catherine; Hendrix, James; et al.
Alzheimer's & dementia / Diagnosis, assessment & disease monitoring Vol. 17, no. 4, p. e70207 Thanks for sharing! #dzne #papers
Alzheimer's & dementia / Diagnosis, assessment & disease monitoring Vol. 17, no. 4, p. e70207 Thanks for sharing! #dzne #papers
How can Alzheimer's disease blood-based biomarkers reach clinical practice?
Perneczky, Robert; Quevenco, Frances-Catherine; Hendrix, James; et al.
Alzheimer's & dementia / Diagnosis, assessment & disease monitoring Vol. 17, no. 4, p. e70207
dlvr.it
November 17, 2025 at 12:32 PM
New paper out: Heterogeneous plasticity of amygdala interneurons in associative learning and extinction: Favila, Natalia; Capece Marsico, Jessica; Pacheco, Catarina M.; et al.
Nature Communications Vol. 16, no. 1, p. 9926
Nature Communications Vol. 16, no. 1, p. 9926
Heterogeneous plasticity of amygdala interneurons in associative learning and extinction
Favila, Natalia; Capece Marsico, Jessica; Pacheco, Catarina M.; et al.
Nature Communications Vol. 16, no. 1, p. 9926
pub.dzne.de
November 14, 2025 at 12:32 PM
New paper out: Heterogeneous plasticity of amygdala interneurons in associative learning and extinction: Favila, Natalia; Capece Marsico, Jessica; Pacheco, Catarina M.; et al.
Nature Communications Vol. 16, no. 1, p. 9926
Nature Communications Vol. 16, no. 1, p. 9926
🥂 Congrats to Marie Homeyer (RG Harald Prüß) on receiving the Felgenhauer Research Award 2025! Her dissertation at DZNE and Charité provides important insights for further development of autoantibody-specific NMDAR-CAAR T-cell therapy and offers valuable insights for current immunotherapy research.
Congratulations to Marie Alice Homeyer on winning the Felgenhauer Research Award 2025! With her dissertation at @dzne.science and #Charité Berlin, she made an essential contribution to the development of autoantibody-specific NMDAR-CAAR T-cell therapy. #dgnkongress2025 #neuroskyence 📷Claudius Pflug
November 14, 2025 at 8:42 AM
🥂 Congrats to Marie Homeyer (RG Harald Prüß) on receiving the Felgenhauer Research Award 2025! Her dissertation at DZNE and Charité provides important insights for further development of autoantibody-specific NMDAR-CAAR T-cell therapy and offers valuable insights for current immunotherapy research.
Reposted by DZNE research center
🎉🏅We congratulate 🌟Zeynep Dokuzluoglu🌟 (German Center for #Neurodegenerative Diseases, #DZNE, Dresden) on winning the FEBS Letters #PosterPrize at the EMBO/EMBL Symposium on #organoids, held in Heidelberg, Germany!
#EESOrgan
@events.embl.org
#EESOrgan
@events.embl.org
November 13, 2025 at 12:17 PM
🎉🏅We congratulate 🌟Zeynep Dokuzluoglu🌟 (German Center for #Neurodegenerative Diseases, #DZNE, Dresden) on winning the FEBS Letters #PosterPrize at the EMBO/EMBL Symposium on #organoids, held in Heidelberg, Germany!
#EESOrgan
@events.embl.org
#EESOrgan
@events.embl.org
Congratulations to DZNE’s Martin Dichgans, Brit Mollenhauer, @joachimschultze.bsky.social and Mikael Simons for their notable scientific impact and ongoing contributions to advancing our understanding of neurodegenerative diseases.
They are listed as Highly Cited Researchers 2025 by @clarivate.com
They are listed as Highly Cited Researchers 2025 by @clarivate.com
November 13, 2025 at 9:12 AM
Congratulations to DZNE’s Martin Dichgans, Brit Mollenhauer, @joachimschultze.bsky.social and Mikael Simons for their notable scientific impact and ongoing contributions to advancing our understanding of neurodegenerative diseases.
They are listed as Highly Cited Researchers 2025 by @clarivate.com
They are listed as Highly Cited Researchers 2025 by @clarivate.com
Reposted by DZNE research center
Out now: Favila, Capece Marsico et al. 2025, Nature Communications: Using longitudinal deep-brain imaging, we report that amygdala interneurons exhibit complex and heterogeneous plasticity during associative learning, at both the single-cell and population level.
👉 www.nature.com/articles/s41...
👉 www.nature.com/articles/s41...
Heterogeneous plasticity of amygdala interneurons in associative learning and extinction - Nature Communications
In this study, the authors uncover how diverse inhibitory interneurons in the amygdala flexibly contribute to fear and safety learning, revealing a key role for inhibition in emotional memory and adap...
www.nature.com
November 12, 2025 at 6:55 PM
Out now: Favila, Capece Marsico et al. 2025, Nature Communications: Using longitudinal deep-brain imaging, we report that amygdala interneurons exhibit complex and heterogeneous plasticity during associative learning, at both the single-cell and population level.
👉 www.nature.com/articles/s41...
👉 www.nature.com/articles/s41...
Reposted by DZNE research center
Latest from the lab: Laura Haetzel finds that excitatory transmission from auditory thalamus to tail of striatum is accompanied by a sparse inhibitory projection. This allows for state-dependent control of striatal output.
www.cell.com/iscience/ful...
www.cell.com/iscience/ful...
Inhibitory inputs from thalamus promote resilient spiking in tail of striatum
Neuroscience; Sensory neuroscience
www.cell.com
November 11, 2025 at 3:04 PM
Latest from the lab: Laura Haetzel finds that excitatory transmission from auditory thalamus to tail of striatum is accompanied by a sparse inhibitory projection. This allows for state-dependent control of striatal output.
www.cell.com/iscience/ful...
www.cell.com/iscience/ful...
Reposted by DZNE research center
Join us for 𝗦𝘁𝗲𝗺 𝗖𝗲𝗹𝗹𝘀 𝗶𝗻 𝗡𝗲𝘂𝗿𝗼𝘀𝗰𝗶𝗲𝗻𝗰𝗲, 𝟮𝟱𝘁𝗵-𝟮𝟳𝘁𝗵 𝗼𝗳 𝗙𝗲𝗯𝗿𝘂𝗮𝗿𝘆, 𝟮𝟬𝟮𝟲 in Tübingen, Germany.
Register here until 30th of November:
👉 www.stemcelltuebingen.com 👈
Please repost and spread the news!
@dzne.science
@hih-tuebingen.bsky.social
@tueneurocampus.bsky.social
@unituebingen.bsky.social
Register here until 30th of November:
👉 www.stemcelltuebingen.com 👈
Please repost and spread the news!
@dzne.science
@hih-tuebingen.bsky.social
@tueneurocampus.bsky.social
@unituebingen.bsky.social
November 6, 2025 at 7:31 AM
Join us for 𝗦𝘁𝗲𝗺 𝗖𝗲𝗹𝗹𝘀 𝗶𝗻 𝗡𝗲𝘂𝗿𝗼𝘀𝗰𝗶𝗲𝗻𝗰𝗲, 𝟮𝟱𝘁𝗵-𝟮𝟳𝘁𝗵 𝗼𝗳 𝗙𝗲𝗯𝗿𝘂𝗮𝗿𝘆, 𝟮𝟬𝟮𝟲 in Tübingen, Germany.
Register here until 30th of November:
👉 www.stemcelltuebingen.com 👈
Please repost and spread the news!
@dzne.science
@hih-tuebingen.bsky.social
@tueneurocampus.bsky.social
@unituebingen.bsky.social
Register here until 30th of November:
👉 www.stemcelltuebingen.com 👈
Please repost and spread the news!
@dzne.science
@hih-tuebingen.bsky.social
@tueneurocampus.bsky.social
@unituebingen.bsky.social
Congratulations to Dr Dr Ahmad Aziz, who has been appointed to a joint professorship at the @unibonn.bsky.social and the DZNE! The appointment was made within the framework of the “Jülich Model”, which enables joint professorial appointments across institutions.
More 👉 www.dzne.de/en/im-fokus/...
More 👉 www.dzne.de/en/im-fokus/...
November 5, 2025 at 1:38 PM
Congratulations to Dr Dr Ahmad Aziz, who has been appointed to a joint professorship at the @unibonn.bsky.social and the DZNE! The appointment was made within the framework of the “Jülich Model”, which enables joint professorial appointments across institutions.
More 👉 www.dzne.de/en/im-fokus/...
More 👉 www.dzne.de/en/im-fokus/...
📆Preview: @embo.org Global Lecture by DZNE scientist Frank Bradke on November 10 at National Brain Research Centre, India
📺https://www.youtube.com/watch?v=3NT0x3oWI8I
📺https://www.youtube.com/watch?v=3NT0x3oWI8I
EMBO Global Lecture Series in India
YouTube video by National Brain Research Centre
www.youtube.com
November 5, 2025 at 10:55 AM
📆Preview: @embo.org Global Lecture by DZNE scientist Frank Bradke on November 10 at National Brain Research Centre, India
📺https://www.youtube.com/watch?v=3NT0x3oWI8I
📺https://www.youtube.com/watch?v=3NT0x3oWI8I
Study: Innovative home care model for #dementia demonstrates practical effectiveness and shows the potential of employing specially qualified nurses with extended roles
👉 scienmag.com/innovative-h...
👉 scienmag.com/innovative-h...
Innovative Home Care Model for Dementia Demonstrates Practical
A groundbreaking clinical trial has brought new hope for the care of individuals living with dementia at home, highlighting the profound impact of specialized nursing roles tailored to this vulnerable
scienmag.com
October 29, 2025 at 8:38 AM
Study: Innovative home care model for #dementia demonstrates practical effectiveness and shows the potential of employing specially qualified nurses with extended roles
👉 scienmag.com/innovative-h...
👉 scienmag.com/innovative-h...
Reposted by DZNE research center
📢 New Preprint 📢
After 3 years of work, I’m proud to present DRIPS (Domain Randomisation for Image-based PVS Segmentation), a new method for accurate & generalisable perivascular space (PVS) segmentation across diverse MRI contrasts and resolutions. @fau.de @dzne.science @svdresearch.bsky.social
After 3 years of work, I’m proud to present DRIPS (Domain Randomisation for Image-based PVS Segmentation), a new method for accurate & generalisable perivascular space (PVS) segmentation across diverse MRI contrasts and resolutions. @fau.de @dzne.science @svdresearch.bsky.social
DRIPS: Domain Randomisation for Image-based Perivascular spaces Segmentation https://www.medrxiv.org/content/10.1101/2025.10.22.25337423v1
October 24, 2025 at 8:42 PM
📢 New Preprint 📢
After 3 years of work, I’m proud to present DRIPS (Domain Randomisation for Image-based PVS Segmentation), a new method for accurate & generalisable perivascular space (PVS) segmentation across diverse MRI contrasts and resolutions. @fau.de @dzne.science @svdresearch.bsky.social
After 3 years of work, I’m proud to present DRIPS (Domain Randomisation for Image-based PVS Segmentation), a new method for accurate & generalisable perivascular space (PVS) segmentation across diverse MRI contrasts and resolutions. @fau.de @dzne.science @svdresearch.bsky.social
🏆Congrats! @cboeger.bsky.social, PhD student at DZNE, was honored with the „3rd annual Drs. Ayeez and Shelena Lalji & Family Student Scholar Award for Repair and Regenerative Mechanisms in ALS“, worth 5,000 US Dollars.
👉 www.dzne.de/en/im-fokus/...
👉 www.dzne.de/en/im-fokus/...
October 23, 2025 at 4:37 PM
🏆Congrats! @cboeger.bsky.social, PhD student at DZNE, was honored with the „3rd annual Drs. Ayeez and Shelena Lalji & Family Student Scholar Award for Repair and Regenerative Mechanisms in ALS“, worth 5,000 US Dollars.
👉 www.dzne.de/en/im-fokus/...
👉 www.dzne.de/en/im-fokus/...
🏆Congrats to Dr. Anna Aschenbrenner for the "Tobias Welte Prize” of the German Sepsis Society, which recognizes her research on the life-saving effects of the drug #dexamethasone in #COVID-19 patients.
👉 www.dzne.de/en/im-fokus/...
👉 www.dzne.de/en/im-fokus/...
October 22, 2025 at 1:33 PM
🏆Congrats to Dr. Anna Aschenbrenner for the "Tobias Welte Prize” of the German Sepsis Society, which recognizes her research on the life-saving effects of the drug #dexamethasone in #COVID-19 patients.
👉 www.dzne.de/en/im-fokus/...
👉 www.dzne.de/en/im-fokus/...
Registration open: eveeno.com/applicationb...
Under the theme “From Genes to Circuits and Behavior”, top neuroscientists - incl. Cori Bargmann, @edvardmoser.bsky.social, Rosa Paolicelli, Maude Baldwin & Zachary Knight - will meet at to explore how neural circuits drive behavior.
Under the theme “From Genes to Circuits and Behavior”, top neuroscientists - incl. Cori Bargmann, @edvardmoser.bsky.social, Rosa Paolicelli, Maude Baldwin & Zachary Knight - will meet at to explore how neural circuits drive behavior.
October 20, 2025 at 12:53 PM
Registration open: eveeno.com/applicationb...
Under the theme “From Genes to Circuits and Behavior”, top neuroscientists - incl. Cori Bargmann, @edvardmoser.bsky.social, Rosa Paolicelli, Maude Baldwin & Zachary Knight - will meet at to explore how neural circuits drive behavior.
Under the theme “From Genes to Circuits and Behavior”, top neuroscientists - incl. Cori Bargmann, @edvardmoser.bsky.social, Rosa Paolicelli, Maude Baldwin & Zachary Knight - will meet at to explore how neural circuits drive behavior.
Reposted by DZNE research center
I'm incredibly honoured and excited to share the great news, that I am awarded #Attempto-Preis 2025! 🎉🥳
This recognition is for our recently published paper, “Layer-specific changes in sensory cortex across the life span in mice and humans.” at #Nature Neuroscience. It truly is a career highlight.
This recognition is for our recently published paper, “Layer-specific changes in sensory cortex across the life span in mice and humans.” at #Nature Neuroscience. It truly is a career highlight.
October 15, 2025 at 6:50 PM
I'm incredibly honoured and excited to share the great news, that I am awarded #Attempto-Preis 2025! 🎉🥳
This recognition is for our recently published paper, “Layer-specific changes in sensory cortex across the life span in mice and humans.” at #Nature Neuroscience. It truly is a career highlight.
This recognition is for our recently published paper, “Layer-specific changes in sensory cortex across the life span in mice and humans.” at #Nature Neuroscience. It truly is a career highlight.
Recording of the recent panel discussion at the @worldhealthsummit.bsky.social on translation in biomedicine 🧠 with dementia researcher and DZNE scientist Emrah Düzel
📺 youtu.be/wiu8UxRMNnY
📺 youtu.be/wiu8UxRMNnY
Rethinking Early-Stage Biomedical Translation | GHL 03
YouTube video by World Health Summit
youtu.be
October 12, 2025 at 7:29 PM
Recording of the recent panel discussion at the @worldhealthsummit.bsky.social on translation in biomedicine 🧠 with dementia researcher and DZNE scientist Emrah Düzel
📺 youtu.be/wiu8UxRMNnY
📺 youtu.be/wiu8UxRMNnY