Davide Seruggia
@dseruggia.bsky.social
Blood, epigenetics and chromatin biology. PI @StAnna_CCRI
& @CeMM_News @ERC_Research | Postdoc @BostonChildrens and @harvardmed | PhD @cnb_csic
& @CeMM_News @ERC_Research | Postdoc @BostonChildrens and @harvardmed | PhD @cnb_csic
Pinned
I am pleased to share a new preprint from my postdoc in the @dseruggia.bsky.social lab. We discovered a structural dependency within the CORE module of the transcriptional coactivator SAGA, which regulates the stability of its histone acetyl transferase, KAT2A.
www.biorxiv.org/content/10.1... 1/n
www.biorxiv.org/content/10.1... 1/n
Disruption of the SAGA CORE triggers collateral degradation of KAT2A
The SAGA transcriptional co-activator complex regulates gene expression through histone acetylation at promoters, mediated by its histone acetyl transferase, KAT2A. While its structure and function ha...
www.biorxiv.org
⬇️ Our latest work on the #SAGA complex - see thread from @paulbatty1.bsky.social ⬇️
Join us for the second iteration of our yearly, St. Anna CCRI Symposium. This year, we will host experts in Cell Fate in Cancer and Development. Don't miss it!
September 9, 2025 at 1:11 PM
Join us for the second iteration of our yearly, St. Anna CCRI Symposium. This year, we will host experts in Cell Fate in Cancer and Development. Don't miss it!
⬇️ Our latest work on the #SAGA complex - see thread from @paulbatty1.bsky.social ⬇️
I am pleased to share a new preprint from my postdoc in the @dseruggia.bsky.social lab. We discovered a structural dependency within the CORE module of the transcriptional coactivator SAGA, which regulates the stability of its histone acetyl transferase, KAT2A.
www.biorxiv.org/content/10.1... 1/n
www.biorxiv.org/content/10.1... 1/n
Disruption of the SAGA CORE triggers collateral degradation of KAT2A
The SAGA transcriptional co-activator complex regulates gene expression through histone acetylation at promoters, mediated by its histone acetyl transferase, KAT2A. While its structure and function ha...
www.biorxiv.org
August 1, 2025 at 8:47 PM
⬇️ Our latest work on the #SAGA complex - see thread from @paulbatty1.bsky.social ⬇️
Reposted by Davide Seruggia
I am pleased to share a new preprint from my postdoc in the @dseruggia.bsky.social lab. We discovered a structural dependency within the CORE module of the transcriptional coactivator SAGA, which regulates the stability of its histone acetyl transferase, KAT2A.
www.biorxiv.org/content/10.1... 1/n
www.biorxiv.org/content/10.1... 1/n
Disruption of the SAGA CORE triggers collateral degradation of KAT2A
The SAGA transcriptional co-activator complex regulates gene expression through histone acetylation at promoters, mediated by its histone acetyl transferase, KAT2A. While its structure and function ha...
www.biorxiv.org
August 1, 2025 at 5:43 PM
I am pleased to share a new preprint from my postdoc in the @dseruggia.bsky.social lab. We discovered a structural dependency within the CORE module of the transcriptional coactivator SAGA, which regulates the stability of its histone acetyl transferase, KAT2A.
www.biorxiv.org/content/10.1... 1/n
www.biorxiv.org/content/10.1... 1/n
This also reminds us what an emotional rollercoaster science can be! :)
🔬 Today’s #EquationsForLife features Adjunct PI @dseruggia.bsky.social’s group (@stanna-ccri.bsky.social)!
The lab studies how noncoding regulatory sequences influence gene control in childhood #leukemia, using the #PoissonDistribution to identify protein binding sites.
🔎 bit.ly/3FHPUlg
The lab studies how noncoding regulatory sequences influence gene control in childhood #leukemia, using the #PoissonDistribution to identify protein binding sites.
🔎 bit.ly/3FHPUlg
June 10, 2025 at 12:52 PM
This also reminds us what an emotional rollercoaster science can be! :)
In a couple of days at Van Swieten Saal in Vienna: join us for an immersive afternoon with six fantastic speakers, and learn more about #pediatric #cancer & #epigenetics.
🚨Registration deadline for St. Anna CCRI #Cancer #Epigenetics Symposium this Sunday, January 12th! More Info and registration here >>> ccri.at/st-anna-ccri...
Don’t miss this incredible opportunity—secure your spot now!
Don’t miss this incredible opportunity—secure your spot now!
January 22, 2025 at 5:39 AM
In a couple of days at Van Swieten Saal in Vienna: join us for an immersive afternoon with six fantastic speakers, and learn more about #pediatric #cancer & #epigenetics.
Reposted by Davide Seruggia
📣Funded #PhDposition! – Pls RT!
Looking for a passionate PhD student to explore cellular crosstalk in #TumorMicroenvironment combining #organoids #scRNAseq &high-res imaging.
Join us @VetmeduniVienna in a vibrant research environment!
#CancerResearch #PhD
👉 euraxess.ec.europa.eu/jobs/302158
Looking for a passionate PhD student to explore cellular crosstalk in #TumorMicroenvironment combining #organoids #scRNAseq &high-res imaging.
Join us @VetmeduniVienna in a vibrant research environment!
#CancerResearch #PhD
👉 euraxess.ec.europa.eu/jobs/302158
January 3, 2025 at 1:10 PM
📣Funded #PhDposition! – Pls RT!
Looking for a passionate PhD student to explore cellular crosstalk in #TumorMicroenvironment combining #organoids #scRNAseq &high-res imaging.
Join us @VetmeduniVienna in a vibrant research environment!
#CancerResearch #PhD
👉 euraxess.ec.europa.eu/jobs/302158
Looking for a passionate PhD student to explore cellular crosstalk in #TumorMicroenvironment combining #organoids #scRNAseq &high-res imaging.
Join us @VetmeduniVienna in a vibrant research environment!
#CancerResearch #PhD
👉 euraxess.ec.europa.eu/jobs/302158
Let's start with a group picture of the seruggialab.com 🐁🩸🧬 :)
November 28, 2024 at 12:08 PM
Let's start with a group picture of the seruggialab.com 🐁🩸🧬 :)