Dr. Mouse
@drmusmusculus.bsky.social
Happily inhabiting cage 42, rack 13, room 02.321 of the animal facility building. Will work hard for chow and publications. Generally unafraid of cats, but animal activists scare the hell out of me.
Reposted by Dr. Mouse
Check out the latest from Mike and I on how to be a scientist in a post-journal world
9/9
thescientistpapers.substack.com/p/how-to-be-...
9/9
thescientistpapers.substack.com/p/how-to-be-...
How to be a scientist in a post-journal world
When we created this site to write about things in science that need to be fixed, we chose not to start with publishing, even though it has been our preoccupation for decades.
thescientistpapers.substack.com
September 8, 2025 at 7:52 PM
Check out the latest from Mike and I on how to be a scientist in a post-journal world
9/9
thescientistpapers.substack.com/p/how-to-be-...
9/9
thescientistpapers.substack.com/p/how-to-be-...
What a shortsighted take. Crypto is bigger than Trump. The dumbass is only interested because he wants to make more easy money for himself and his friends. That is all he cares about.
September 5, 2025 at 12:36 PM
What a shortsighted take. Crypto is bigger than Trump. The dumbass is only interested because he wants to make more easy money for himself and his friends. That is all he cares about.
Maybe you got only 3'UTRs and not introns bc drosophila introns are too small so you're dealing with a biased coin toss. Great opportunity to shift towards a furry cute mammal model that will drown you in paperwork and leave you bankrupt! ;)
August 18, 2025 at 11:07 AM
Maybe you got only 3'UTRs and not introns bc drosophila introns are too small so you're dealing with a biased coin toss. Great opportunity to shift towards a furry cute mammal model that will drown you in paperwork and leave you bankrupt! ;)
not an expert but: occasional intron retention as a mechanism for antisense capture of these guys? Intron retention higher in germ cells (evolutionary benefits to expose sneaky TEs hitchhiking euchromatin?) + offer a sorting mech for mRNAs via weird spliceosome, NMD, or ribosome engagement or else.
August 18, 2025 at 11:03 AM
not an expert but: occasional intron retention as a mechanism for antisense capture of these guys? Intron retention higher in germ cells (evolutionary benefits to expose sneaky TEs hitchhiking euchromatin?) + offer a sorting mech for mRNAs via weird spliceosome, NMD, or ribosome engagement or else.
cannot argue with that. you all work for the corporations that manage to hijack science while profiting from its work AND convincing scientists that what you provide is the best proxy for career success. Masterclass in Stockholm syndrome.
August 17, 2025 at 3:05 PM
cannot argue with that. you all work for the corporations that manage to hijack science while profiting from its work AND convincing scientists that what you provide is the best proxy for career success. Masterclass in Stockholm syndrome.