Dr Lipid
@drlipid.bsky.social
Longtime Lipid/Lipoprotein Educator with an extensive resume including Associate Editor of Journal of Clinical Lipidology. Practiced in NJ for 37 years. Has done 4000 lectures in all 50 states & authored many publications. Has two major awards from NLA
LDL Education Post 2: More important LDL facts that for the most part are not taught, hard to find and therefore so frequently mischaracterized (misused) on social media and sadly in too many manuscripts. Enjoy. @nationallipid.bsky.social @aspcardio.bsky.social @familyheartfdn.bsky.social
November 24, 2025 at 12:26 AM
LDL Education Post 2: More important LDL facts that for the most part are not taught, hard to find and therefore so frequently mischaracterized (misused) on social media and sadly in too many manuscripts. Enjoy. @nationallipid.bsky.social @aspcardio.bsky.social @familyheartfdn.bsky.social
LDL education: (1) never confuse the term LDL, the name of a specific lipoprotein with LDL-P a particle concentration metric. (2) LDL is named by its density via ultracentrifugation (3) What is LDL size, peak particle size or Pattern? (4) How many LDL particles exist per liter of plasma?
November 23, 2025 at 1:18 AM
LDL education: (1) never confuse the term LDL, the name of a specific lipoprotein with LDL-P a particle concentration metric. (2) LDL is named by its density via ultracentrifugation (3) What is LDL size, peak particle size or Pattern? (4) How many LDL particles exist per liter of plasma?
Many thanks to FUNDACION CARDIOINFANTIL of Bogota Columbia, for the invitation and high honor to lecture virtually at their Cardiovascular Congress today on the topic of Lipid and Lipoprotein complexities. It was a pleasure to join with my long-time Argentinian colleague & Lipidologist Pablo Coral
October 3, 2025 at 12:21 AM
Many thanks to FUNDACION CARDIOINFANTIL of Bogota Columbia, for the invitation and high honor to lecture virtually at their Cardiovascular Congress today on the topic of Lipid and Lipoprotein complexities. It was a pleasure to join with my long-time Argentinian colleague & Lipidologist Pablo Coral
What is the size of the thrombus in a coronary artery that can send one to Heaven or the CCU? Coronary artery lumens are quite small, and a cholesterol-rich plaque rupture or erosion will induce a thrombus. A tiny thrombus will partially block (cause ischemia) or totally block (cause infarction).
September 21, 2025 at 12:32 PM
What is the size of the thrombus in a coronary artery that can send one to Heaven or the CCU? Coronary artery lumens are quite small, and a cholesterol-rich plaque rupture or erosion will induce a thrombus. A tiny thrombus will partially block (cause ischemia) or totally block (cause infarction).
On this podcast, I along with an oncologist (speaking about cancer) and I on lipids had the opportunity to educate a very different crowd - the Finance World - I was a guest on Jimmie Lee's The Bull of Wall Street Podcast - My section starts at 21:23 - Enjoy www.youtube.com/watch?v=FPSE...
September 19, 2025 at 11:17 PM
On this podcast, I along with an oncologist (speaking about cancer) and I on lipids had the opportunity to educate a very different crowd - the Finance World - I was a guest on Jimmie Lee's The Bull of Wall Street Podcast - My section starts at 21:23 - Enjoy www.youtube.com/watch?v=FPSE...
To further confuse the EPA vs EPA+DHA story. Here is new data from STRENGTH showing EPA + DHA reduced MACE in Asian patients. Authors had no reasons but perhaps due to Asian incidence of IR and TG issues. www.atherosclerosis-journal.com/article/S002...
September 17, 2025 at 4:50 PM
To further confuse the EPA vs EPA+DHA story. Here is new data from STRENGTH showing EPA + DHA reduced MACE in Asian patients. Authors had no reasons but perhaps due to Asian incidence of IR and TG issues. www.atherosclerosis-journal.com/article/S002...
DHA is crucial for maintaining brain neuron integrity and may inhibit tau phosphorylation. High doses (0.9–1.8 g/d) of DHA/EPA have shown improvements in cognitive function, while low doses (0.3–0.7 g/d) did not. www.sciencedirect.com/science/article/pii/S0002916523463204?via%3Dihub
September 16, 2025 at 4:01 PM
DHA is crucial for maintaining brain neuron integrity and may inhibit tau phosphorylation. High doses (0.9–1.8 g/d) of DHA/EPA have shown improvements in cognitive function, while low doses (0.3–0.7 g/d) did not. www.sciencedirect.com/science/article/pii/S0002916523463204?via%3Dihub
"Understanding the Lipid Panel" - next are insights on Non-HDL-C which refers (1) to the mass (weight) in mg of cholesterol within all of the apoB-containing lipoproteins per dL or (2) the number (in mmols) of cholesterol molecules in all the apoB-particles per L.
September 1, 2025 at 11:54 PM
"Understanding the Lipid Panel" - next are insights on Non-HDL-C which refers (1) to the mass (weight) in mg of cholesterol within all of the apoB-containing lipoproteins per dL or (2) the number (in mmols) of cholesterol molecules in all the apoB-particles per L.
Part 2 of my discussion with @_CynthiaThurlow on her Everyday Wellness Podcast where we continue the journey into lipid/lipoprotein issues with an emphasis on women www.youtube.com/watch?v=IoKZvN8BWbg&t=139s @aspcardio.bsky.social @familyheartfdn.bsky.social @nationallipid.bsky.social
August 27, 2025 at 4:18 PM
Part 2 of my discussion with @_CynthiaThurlow on her Everyday Wellness Podcast where we continue the journey into lipid/lipoprotein issues with an emphasis on women www.youtube.com/watch?v=IoKZvN8BWbg&t=139s @aspcardio.bsky.social @familyheartfdn.bsky.social @nationallipid.bsky.social
Insights on HDL-C reported as (1) mass (weight in mg) of all of the cholesterol molecules within all of the HDLs per dL of plasma or (2) the NUMBER of all of the cholesterol molecules in HDLs er liter [mmols). HDL-C or HDL-P have no relationship HDL functionality or reverse cholesterol transport
August 22, 2025 at 1:24 PM
Insights on HDL-C reported as (1) mass (weight in mg) of all of the cholesterol molecules within all of the HDLs per dL of plasma or (2) the NUMBER of all of the cholesterol molecules in HDLs er liter [mmols). HDL-C or HDL-P have no relationship HDL functionality or reverse cholesterol transport
"Understanding the Lipid Panel" - LDL-C reported as (1) the mass (weight in mg) or the # (mmols) of all of the cholesterol molecules within all of the IDLs and LDLs circulating in a dL of plasma LDL-C is calculated, directly measured, or assayed as the gold standard assay termed beta-quantification
August 18, 2025 at 4:48 PM
"Understanding the Lipid Panel" - LDL-C reported as (1) the mass (weight in mg) or the # (mmols) of all of the cholesterol molecules within all of the IDLs and LDLs circulating in a dL of plasma LDL-C is calculated, directly measured, or assayed as the gold standard assay termed beta-quantification
Revisiting my series "Understanding the Lipid Panel" - 1 metric at a time starting with Total Cholesterol. The lipid panel reports lipid mass concentrations but not the lipoprotein concentrations. In essence lipid concentrations are simply guesstimates or surrogates of lipoprotein concentrations.
August 14, 2025 at 7:23 PM
Revisiting my series "Understanding the Lipid Panel" - 1 metric at a time starting with Total Cholesterol. The lipid panel reports lipid mass concentrations but not the lipoprotein concentrations. In essence lipid concentrations are simply guesstimates or surrogates of lipoprotein concentrations.
More fuel to demolish the cholesterol deniers - Combining LDL-C with LDL-Years LDL-C X age (yrs) www.jacc.org/doi/10.1016/j.jacc.2018.06.046 @nationallipid.bsky.social @aspcardio.bsky.social @familyheartfdn.bsky.social
August 13, 2025 at 6:29 PM
More fuel to demolish the cholesterol deniers - Combining LDL-C with LDL-Years LDL-C X age (yrs) www.jacc.org/doi/10.1016/j.jacc.2018.06.046 @nationallipid.bsky.social @aspcardio.bsky.social @familyheartfdn.bsky.social
Lipoproteinology Lessons - Some interesting but sobering facts about LDL and HDL particle concentrations @aspcardio.bsky.social @nationallipid.bsky.social @escardio.bsky.social @familyheartfdn.bsky.social
August 11, 2025 at 4:04 PM
Lipoproteinology Lessons - Some interesting but sobering facts about LDL and HDL particle concentrations @aspcardio.bsky.social @nationallipid.bsky.social @escardio.bsky.social @familyheartfdn.bsky.social
Here is a thorough updated meta-analysis of the lipid-lowering efficacy of Obicetrapib: looking at a comprehensive review of randomized controlled trials. An amazing new drug. Hard to imagine a better novel primary care drug. www.lipidjournal.com/action/showPdf?pii=S1933-2874%2825%2900356-3
August 7, 2025 at 3:28 PM
Here is a thorough updated meta-analysis of the lipid-lowering efficacy of Obicetrapib: looking at a comprehensive review of randomized controlled trials. An amazing new drug. Hard to imagine a better novel primary care drug. www.lipidjournal.com/action/showPdf?pii=S1933-2874%2825%2900356-3
Lipidologists: Nice study by my friends at NIH on the importance of HDLs, not LDLs, supplying cholesterol to steroidogenic tissues. HDLs in addition to Reverse Cholesterol Transport also do Forward Cholesterol Transport. Check with author @RZubiranS for reprints pubmed.ncbi.nlm.nih.gov/40767551/
August 7, 2025 at 1:04 PM
Lipidologists: Nice study by my friends at NIH on the importance of HDLs, not LDLs, supplying cholesterol to steroidogenic tissues. HDLs in addition to Reverse Cholesterol Transport also do Forward Cholesterol Transport. Check with author @RZubiranS for reprints pubmed.ncbi.nlm.nih.gov/40767551/
Here is an immense treatise on HDLs from @aspcardio.bsky.social which is for advanced students @ASPCardio "The HDL code is yet to be fully deciphered. A polymolecular assembly as complex as mature HDL is not a simple task to study." www.sciencedirect.com/science/article/pii/S2666667725001436
July 22, 2025 at 11:57 AM
Here is an immense treatise on HDLs from @aspcardio.bsky.social which is for advanced students @ASPCardio "The HDL code is yet to be fully deciphered. A polymolecular assembly as complex as mature HDL is not a simple task to study." www.sciencedirect.com/science/article/pii/S2666667725001436
Clinical Chemistry - Lipoprotein Metrics - also a lot to digest @nationallipid.bsky.social @eassociety.bsky.social @aspcardio.bsky.social @familyheartfdn.bsky.social
July 11, 2025 at 4:03 PM
Clinical Chemistry - Lipoprotein Metrics - also a lot to digest @nationallipid.bsky.social @eassociety.bsky.social @aspcardio.bsky.social @familyheartfdn.bsky.social
Here are some lipid/lipoprotein tutorial slides to help all better master the complexities involved. So much to master! @nationallipid.bsky.social @aspcardio.bsky.social @escardio.bsky.social @familyheartfdn.bsky.social @eassociety.bsky.social
July 11, 2025 at 12:29 PM
Here are some lipid/lipoprotein tutorial slides to help all better master the complexities involved. So much to master! @nationallipid.bsky.social @aspcardio.bsky.social @escardio.bsky.social @familyheartfdn.bsky.social @eassociety.bsky.social
Reposting my recent Lp-IR Score graphic which contained a mistake caught by a vigilant Lipidaholic. @nationallipid.bsky.social @aspcardio.bsky.social @escardio.bsky.social
July 7, 2025 at 11:06 PM
Reposting my recent Lp-IR Score graphic which contained a mistake caught by a vigilant Lipidaholic. @nationallipid.bsky.social @aspcardio.bsky.social @escardio.bsky.social
Here is a useful chart of reference ranges for those using the NMR derived Lipoprotein Insulin Resistance Score (LP-IR Score). These metrics do not apply to such metrics derived by Ion Mobility Transfer separation of lipoproteins (Quest methodology) @nationallipid.bsky.social @aspcardio.bsky.social
July 7, 2025 at 3:09 PM
Here is a useful chart of reference ranges for those using the NMR derived Lipoprotein Insulin Resistance Score (LP-IR Score). These metrics do not apply to such metrics derived by Ion Mobility Transfer separation of lipoproteins (Quest methodology) @nationallipid.bsky.social @aspcardio.bsky.social
Important update on Alzheimer's -Need to start prevention much earlier than waiting for symptoms. www.nih.gov/news-events/news-releases/alzheimer-s-disease-may-damage-brain-two-phases @nationallipid.bsky.social @aspcardio.bsky.social @escardio.bsky.social
July 5, 2025 at 3:51 PM
Important update on Alzheimer's -Need to start prevention much earlier than waiting for symptoms. www.nih.gov/news-events/news-releases/alzheimer-s-disease-may-damage-brain-two-phases @nationallipid.bsky.social @aspcardio.bsky.social @escardio.bsky.social
For those who want to view my lecture on Brain and Lipids - here is the link - 1 hour and twenty minutes www.functionalmedicineuniversity.com/Lipids3-Days... @nationallipid.bsky.social @aspcardio.bsky.social @escardio.bsky.social
June 25, 2025 at 11:23 PM
For those who want to view my lecture on Brain and Lipids - here is the link - 1 hour and twenty minutes www.functionalmedicineuniversity.com/Lipids3-Days... @nationallipid.bsky.social @aspcardio.bsky.social @escardio.bsky.social
For those who missed it last night - Here is my Lecture (audio and animated slides) on Lp(a) to the Functional Medicine University - We had > 500 viewers www.functionalmedicineuniversity.com/LipoproteinLittlea.mp4 @familyheartfdn.bsky.social @nationallipid.bsky.social @aspcardio.bsky.social
June 18, 2025 at 3:33 PM
For those who missed it last night - Here is my Lecture (audio and animated slides) on Lp(a) to the Functional Medicine University - We had > 500 viewers www.functionalmedicineuniversity.com/LipoproteinLittlea.mp4 @familyheartfdn.bsky.social @nationallipid.bsky.social @aspcardio.bsky.social
My second lecture for Functional Medicine University is June 17 (tomorrow) - Register for this free informative 1.5-hour lecture on Lipoprotein(a) with my one-of-a-kind graphics at htts://register.gotowebinar.com/register/1416372629896094814 @nationallipid.bsky.social @aspcardio.bsky.social
June 16, 2025 at 11:54 AM
My second lecture for Functional Medicine University is June 17 (tomorrow) - Register for this free informative 1.5-hour lecture on Lipoprotein(a) with my one-of-a-kind graphics at htts://register.gotowebinar.com/register/1416372629896094814 @nationallipid.bsky.social @aspcardio.bsky.social