Dr Dan Campbell-Meiklejohn
@drdanielcm.bsky.social
Research psychologist,
neuroscientist and associate professor at the University of Sussex looking at interoception, affective processing, empathy, social motivation and kindness through the lens of neuroimaging, physiology, pharmacology, and behaviour
neuroscientist and associate professor at the University of Sussex looking at interoception, affective processing, empathy, social motivation and kindness through the lens of neuroimaging, physiology, pharmacology, and behaviour
Also preliminary is that the neural SSRI effect on cardiac interoception in the amygdala predicted our previously published effects metacognitive cardiac interoceptive insight (this is in the supplemental material). 8/10
June 6, 2024 at 6:20 PM
Also preliminary is that the neural SSRI effect on cardiac interoception in the amygdala predicted our previously published effects metacognitive cardiac interoceptive insight (this is in the supplemental material). 8/10
Exploratory post hoc analysis also showed that the effects of the SSRI on the stomach response in the amygdala predicted effects on anxiety (increases and decreases) across the sample. 7/10
June 6, 2024 at 6:20 PM
Exploratory post hoc analysis also showed that the effects of the SSRI on the stomach response in the amygdala predicted effects on anxiety (increases and decreases) across the sample. 7/10
Excitingly, we replicated the already-known interoception response that is proportional to anxiety in the anterior insula on a placebo. But the SSRI BREAKS that link, with a significant change in the interoception-anxiety relationship in the region. 6/10
June 6, 2024 at 6:18 PM
Excitingly, we replicated the already-known interoception response that is proportional to anxiety in the anterior insula on a placebo. But the SSRI BREAKS that link, with a significant change in the interoception-anxiety relationship in the region. 6/10
This SSRI effect also happened during attention to the heart in the amygdala, possibly reflecting an effect on the integration of cardiac interoception in affective processes 5/10
June 6, 2024 at 6:18 PM
This SSRI effect also happened during attention to the heart in the amygdala, possibly reflecting an effect on the integration of cardiac interoception in affective processes 5/10
The SSRI reduced viscerosensory (posterior insula and surrounding) and integrative (amygdala) interoceptive processing of attended stomach sensation on BOTH sides of the brain (relative to effects on exteroception). 4/10
June 6, 2024 at 6:17 PM
The SSRI reduced viscerosensory (posterior insula and surrounding) and integrative (amygdala) interoceptive processing of attended stomach sensation on BOTH sides of the brain (relative to effects on exteroception). 4/10
21 healthy volunteers focused their attention on their stomach, heart or a pulsing visual stimulus. They did this on a single oral SSRI dose (20mg citalopram) and, at another time, did the same on a placebo. This design is WITHIN-subjects, people! 42 scan sessions. 3/10
June 6, 2024 at 6:17 PM
21 healthy volunteers focused their attention on their stomach, heart or a pulsing visual stimulus. They did this on a single oral SSRI dose (20mg citalopram) and, at another time, did the same on a placebo. This design is WITHIN-subjects, people! 42 scan sessions. 3/10