Dr. David Boulware, MD MPH
@drboulware.bsky.social
Professor of Medicine at U of MN; Practicing infectious disease doc; budding mycologist; interested in cryptococcal & TB meningitis. Ran some RCTs during COVID, but more excited to return to focus on RCTs on HIV-related meningitis & advanced HIV disease
Reposted by Dr. David Boulware, MD MPH
As @gregggonsalves.bsky.social said, here is the main winner in the forced departure of Carl Dieffenbach.
November 24, 2025 at 11:59 AM
As @gregggonsalves.bsky.social said, here is the main winner in the forced departure of Carl Dieffenbach.
Reposted by Dr. David Boulware, MD MPH
New "Osterholm Update" podcast episode! @mtosterholm & @cvdall review the latest flu trends and how this year's vaccine compares to circulating strains. Dr. O also discusses H5N1 impact on mammals in Antarctica and answers an ID Query on infant botulism
www.cidrap.umn.edu/a...
www.cidrap.umn.edu/a...
November 20, 2025 at 7:13 PM
New "Osterholm Update" podcast episode! @mtosterholm & @cvdall review the latest flu trends and how this year's vaccine compares to circulating strains. Dr. O also discusses H5N1 impact on mammals in Antarctica and answers an ID Query on infant botulism
www.cidrap.umn.edu/a...
www.cidrap.umn.edu/a...
Why are CLSI breakpoints for Candida so low? 8 mcg/mL is considered "resistant" in Candida yet this is the MIC50 for Cryptococcus species where we just use higher dose fluconazole 800-1200mg/day.
Is the problem that the FDA package insert says the Candida dose is 100 mg or 200mg once daily?
Is the problem that the FDA package insert says the Candida dose is 100 mg or 200mg once daily?
November 20, 2025 at 5:26 PM
Why are CLSI breakpoints for Candida so low? 8 mcg/mL is considered "resistant" in Candida yet this is the MIC50 for Cryptococcus species where we just use higher dose fluconazole 800-1200mg/day.
Is the problem that the FDA package insert says the Candida dose is 100 mg or 200mg once daily?
Is the problem that the FDA package insert says the Candida dose is 100 mg or 200mg once daily?
Reposted by Dr. David Boulware, MD MPH
#idboardreview A Pt w/travel to Mexico a few months prior (drank tap water, ate raw vegetables) noticed a small worm-like object on inner surface of her lower lip. She removed the object with a needle. Dx? #medEd #idmeded #IDsky #parasitology
November 19, 2025 at 11:17 PM
#idboardreview A Pt w/travel to Mexico a few months prior (drank tap water, ate raw vegetables) noticed a small worm-like object on inner surface of her lower lip. She removed the object with a needle. Dx? #medEd #idmeded #IDsky #parasitology
Is a 28 Point Munich Agrement the solution?
Peace in Our Time.
Peace in Our Time.
Following the Russian missile strike on Ternopil, 26 people have been confirmed killed and 22 remain missing. Search and rescue efforts are still underway.
November 20, 2025 at 2:11 PM
Is a 28 Point Munich Agrement the solution?
Peace in Our Time.
Peace in Our Time.
Webinar: Attributes of pathogen genomic data platforms supporting timely and equitable sharing - Pathogen Forum.
24-Nov-2025, 1 pm CET / 7am EST
pathogenforum.org/webinar-attr...
24-Nov-2025, 1 pm CET / 7am EST
pathogenforum.org/webinar-attr...
Webinar: Attributes of pathogen genomic data platforms supporting timely and equitable sharing - Pathogen Forum
This is part of a series organized by WHO/IPSN in collaboration with the Pathogen Genomics Funders Forum.
pathogenforum.org
November 19, 2025 at 1:47 PM
Webinar: Attributes of pathogen genomic data platforms supporting timely and equitable sharing - Pathogen Forum.
24-Nov-2025, 1 pm CET / 7am EST
pathogenforum.org/webinar-attr...
24-Nov-2025, 1 pm CET / 7am EST
pathogenforum.org/webinar-attr...
Great northern lights night in Minnesota
November 12, 2025 at 2:48 AM
Great northern lights night in Minnesota
Should one be flattered when a published manuscript that is clearly AI written hallucinates and creates citations by you that you never wrote? Paper is not very good, omitting from the abstract use of a bad CrAg test which has poor performance.
What should one do? Contact editor? Or author?
What should one do? Contact editor? Or author?
November 9, 2025 at 1:04 PM
Should one be flattered when a published manuscript that is clearly AI written hallucinates and creates citations by you that you never wrote? Paper is not very good, omitting from the abstract use of a bad CrAg test which has poor performance.
What should one do? Contact editor? Or author?
What should one do? Contact editor? Or author?
Reposted by Dr. David Boulware, MD MPH
Career Opportunity! The California Department of Public Health, TB Control Branch is recruiting for an epidemiologist position.
Interested persons may apply via this website: sjobs.brassring.com/TGnewUI/Sear...
#Tuberculosis #TBSKy
Interested persons may apply via this website: sjobs.brassring.com/TGnewUI/Sear...
#Tuberculosis #TBSKy
Job Search Welcome | University of California San Francisco
Search for Internet job openings.
sjobs.brassring.com
October 24, 2025 at 5:23 PM
Career Opportunity! The California Department of Public Health, TB Control Branch is recruiting for an epidemiologist position.
Interested persons may apply via this website: sjobs.brassring.com/TGnewUI/Sear...
#Tuberculosis #TBSKy
Interested persons may apply via this website: sjobs.brassring.com/TGnewUI/Sear...
#Tuberculosis #TBSKy
Is there a fungus amongst us?
Dr. Fungus App for medical mycology on your phone.
Apple iOS Store: apps.apple.com/us/app/dr-fu...
Google Play Store: play.google.com/store/apps/d...
Dr. Fungus App for medical mycology on your phone.
Apple iOS Store: apps.apple.com/us/app/dr-fu...
Google Play Store: play.google.com/store/apps/d...
Dr. Fungus
The Dr. Fungus app serves as a companion to the official Dr. Fungus website, the Mycoses Study Group Education and Research Consortium resource for fungal disease education. This app provides up-to-d...
apps.apple.com
October 22, 2025 at 12:48 AM
Is there a fungus amongst us?
Dr. Fungus App for medical mycology on your phone.
Apple iOS Store: apps.apple.com/us/app/dr-fu...
Google Play Store: play.google.com/store/apps/d...
Dr. Fungus App for medical mycology on your phone.
Apple iOS Store: apps.apple.com/us/app/dr-fu...
Google Play Store: play.google.com/store/apps/d...
Insurance via ACA marketplace is projected to rise by 21% in Minnesota in 2026.
October 16, 2025 at 12:04 AM
Insurance via ACA marketplace is projected to rise by 21% in Minnesota in 2026.
No longer... CDC EIS RIF'ed.
October 11, 2025 at 1:57 AM
No longer... CDC EIS RIF'ed.
Reposted by Dr. David Boulware, MD MPH
Vaccine for typhoid, invasive Salmonella shows promise in phase 1 trial
Researchers say the investigational three-strain vaccine produced a strong immune response and was well-tolerated in its first human trial.
www.cidrap.umn.edu/s...
Researchers say the investigational three-strain vaccine produced a strong immune response and was well-tolerated in its first human trial.
www.cidrap.umn.edu/s...
October 8, 2025 at 8:31 PM
Vaccine for typhoid, invasive Salmonella shows promise in phase 1 trial
Researchers say the investigational three-strain vaccine produced a strong immune response and was well-tolerated in its first human trial.
www.cidrap.umn.edu/s...
Researchers say the investigational three-strain vaccine produced a strong immune response and was well-tolerated in its first human trial.
www.cidrap.umn.edu/s...
Predictive value of C-reactive protein for hospitalization and mortality among people with advanced HIV disease in Uganda receiving the WHO-recommended package of care
Nice paper by U of MN MD/PhD student Eli Schwartz on behalf of the ENCORE Team.
track.smtpsendmail.com/9032119/c?p=...
Nice paper by U of MN MD/PhD student Eli Schwartz on behalf of the ENCORE Team.
track.smtpsendmail.com/9032119/c?p=...
Predictive value of C-reactive protein for hospitalization and mortality among people with advanced HIV disease in Uganda receiving the WHO-recommended package of care
Among Ugandan outpatients with advanced HIV, elevated serum CRP (≥10 mg/L) predicted 30-day risk of opportunistic infection, hospitalization, and death. Ea
track.smtpsendmail.com
October 8, 2025 at 5:54 PM
Predictive value of C-reactive protein for hospitalization and mortality among people with advanced HIV disease in Uganda receiving the WHO-recommended package of care
Nice paper by U of MN MD/PhD student Eli Schwartz on behalf of the ENCORE Team.
track.smtpsendmail.com/9032119/c?p=...
Nice paper by U of MN MD/PhD student Eli Schwartz on behalf of the ENCORE Team.
track.smtpsendmail.com/9032119/c?p=...
Twin Cities Marathon Day.
Brunch with neighbors on front lawn cheering on runners.
Brunch with neighbors on front lawn cheering on runners.
October 5, 2025 at 2:51 PM
Twin Cities Marathon Day.
Brunch with neighbors on front lawn cheering on runners.
Brunch with neighbors on front lawn cheering on runners.
Excited to speak at UT Houston-Methodist on Friday on "Innovative Clinical Trial Designs in ID"
First time I have been back to Houston in 26 years. It's still hot... and even more buildings on medical campus.
First time I have been back to Houston in 26 years. It's still hot... and even more buildings on medical campus.
October 2, 2025 at 8:16 PM
Excited to speak at UT Houston-Methodist on Friday on "Innovative Clinical Trial Designs in ID"
First time I have been back to Houston in 26 years. It's still hot... and even more buildings on medical campus.
First time I have been back to Houston in 26 years. It's still hot... and even more buildings on medical campus.
Mycosis Study Group has released DrFungus app for phones as a reference companion for yeast and mold infections.
iPhone apps.apple.com/us/app/dr-fu...
Android play.google.com/store/apps/d...
App designed by Dr Matt Pullen. @msgerc.bsky.social
iPhone apps.apple.com/us/app/dr-fu...
Android play.google.com/store/apps/d...
App designed by Dr Matt Pullen. @msgerc.bsky.social
Dr. Fungus
The Dr. Fungus app serves as a companion to the official Dr. Fungus website, the Mycoses Study Group Education and Research Consortium resource for fungal disease education. This app provides up-to-d...
apps.apple.com
September 18, 2025 at 5:54 AM
Mycosis Study Group has released DrFungus app for phones as a reference companion for yeast and mold infections.
iPhone apps.apple.com/us/app/dr-fu...
Android play.google.com/store/apps/d...
App designed by Dr Matt Pullen. @msgerc.bsky.social
iPhone apps.apple.com/us/app/dr-fu...
Android play.google.com/store/apps/d...
App designed by Dr Matt Pullen. @msgerc.bsky.social
Reposted by Dr. David Boulware, MD MPH
More Than 20 Medical Groups Call For RFK Jr. To Resign
#IDSky #MedSky
www.idsociety.org/news--public...
#IDSky #MedSky
www.idsociety.org/news--public...
Joint statement calling for Secretary Kennedy resignation
www.idsociety.org
September 5, 2025 at 12:10 PM
More Than 20 Medical Groups Call For RFK Jr. To Resign
#IDSky #MedSky
www.idsociety.org/news--public...
#IDSky #MedSky
www.idsociety.org/news--public...
Reposted by Dr. David Boulware, MD MPH
Two studies, same signal👇
📊 COVID-OUT RCT: 41% ↓ long COVID with 14d metformin (1500 mg/day by Day 6).
📊 CID UK cohort (766k pts): 64% ↓ long COVID if metformin started within 90d.
Cheap, safe, generic drug. Replication across RCT + real world = 🔥
#MedSky
📊 COVID-OUT RCT: 41% ↓ long COVID with 14d metformin (1500 mg/day by Day 6).
📊 CID UK cohort (766k pts): 64% ↓ long COVID if metformin started within 90d.
Cheap, safe, generic drug. Replication across RCT + real world = 🔥
#MedSky
Effect of Metformin on the Risk of Post-coronavirus Disease 2019 Condition Among Individuals With Overweight or Obese: A Population-based Retrospective Cohort Study
Early metformin treatment in overweight or obese adults with recent coronavirus disease 2019 infection significantly reduces the risk of developing post–co
academic.oup.com
September 3, 2025 at 7:50 PM
Two studies, same signal👇
📊 COVID-OUT RCT: 41% ↓ long COVID with 14d metformin (1500 mg/day by Day 6).
📊 CID UK cohort (766k pts): 64% ↓ long COVID if metformin started within 90d.
Cheap, safe, generic drug. Replication across RCT + real world = 🔥
#MedSky
📊 COVID-OUT RCT: 41% ↓ long COVID with 14d metformin (1500 mg/day by Day 6).
📊 CID UK cohort (766k pts): 64% ↓ long COVID if metformin started within 90d.
Cheap, safe, generic drug. Replication across RCT + real world = 🔥
#MedSky
Are childhood vaccination requirement to attend public school (with a parental opt out) equivalent to slavery? No.
September 4, 2025 at 3:26 AM
Are childhood vaccination requirement to attend public school (with a parental opt out) equivalent to slavery? No.
IDSA @idsainfo.bsky.social calls for the resignation of RFK Jr. as "Health" Secretary.
Are there other organizations which will call for this?
www.idsociety.org/news--public...
Are there other organizations which will call for this?
www.idsociety.org/news--public...
Joint statement calling for Secretary Kennedy resignation
www.idsociety.org
September 4, 2025 at 12:36 AM
IDSA @idsainfo.bsky.social calls for the resignation of RFK Jr. as "Health" Secretary.
Are there other organizations which will call for this?
www.idsociety.org/news--public...
Are there other organizations which will call for this?
www.idsociety.org/news--public...
Reposted by Dr. David Boulware, MD MPH
#Metformin reduces risk on developing #PCC from 27,9% to 11.2% if started within 90 days of #SARS-COV-2 infection in #overweight/#obese patients in real-world settings (624 308 patients propensity-score)
Risk Difference At 1 y (%) -12,58%
Adjusted Hazard Ratio 0.36 academic.oup.com/cid/advance-...
Risk Difference At 1 y (%) -12,58%
Adjusted Hazard Ratio 0.36 academic.oup.com/cid/advance-...
Effect of Metformin on the Risk of Post-coronavirus Disease 2019 Condition Among Individuals With Overweight or Obese: A Population-based Retrospective Cohort Study
Early metformin treatment in overweight or obese adults with recent coronavirus disease 2019 infection significantly reduces the risk of developing post–co
academic.oup.com
September 2, 2025 at 6:57 AM
#Metformin reduces risk on developing #PCC from 27,9% to 11.2% if started within 90 days of #SARS-COV-2 infection in #overweight/#obese patients in real-world settings (624 308 patients propensity-score)
Risk Difference At 1 y (%) -12,58%
Adjusted Hazard Ratio 0.36 academic.oup.com/cid/advance-...
Risk Difference At 1 y (%) -12,58%
Adjusted Hazard Ratio 0.36 academic.oup.com/cid/advance-...
Why is OFID publishing a #covid study from 2021 reporting #paxlovid secondary trial results by Pfizer in high risk unvaccinated results - while burying the same results in the lower risk trial. @ofidjournal.bsky.social
Low risk results were presented at IDweek
academic.oup.com/ofid/article...
Low risk results were presented at IDweek
academic.oup.com/ofid/article...
Patient-Reported Outcomes of Nirmatrelvir Treatment for High-Risk, Nonhospitalized Adults With Symptomatic COVID-19
In a phase 2/3 trial, high-risk adults with confirmed symptomatic COVID-19 receiving nirmatrelvir/ritonavir twice daily for 5 days reported global impressi
academic.oup.com
September 2, 2025 at 12:25 PM
Why is OFID publishing a #covid study from 2021 reporting #paxlovid secondary trial results by Pfizer in high risk unvaccinated results - while burying the same results in the lower risk trial. @ofidjournal.bsky.social
Low risk results were presented at IDweek
academic.oup.com/ofid/article...
Low risk results were presented at IDweek
academic.oup.com/ofid/article...
America First? Not When It Comes to Your Health. www.nytimes.com/2025/08/24/o...
Money saved by impoundment. Opportunities lost. Video explains such opportunities to advance medical research to improve Anetjcan’s health
Money saved by impoundment. Opportunities lost. Video explains such opportunities to advance medical research to improve Anetjcan’s health
Opinion | America First? Not When It Comes to Your Health.
www.nytimes.com
August 25, 2025 at 4:16 AM
America First? Not When It Comes to Your Health. www.nytimes.com/2025/08/24/o...
Money saved by impoundment. Opportunities lost. Video explains such opportunities to advance medical research to improve Anetjcan’s health
Money saved by impoundment. Opportunities lost. Video explains such opportunities to advance medical research to improve Anetjcan’s health
Reposted by Dr. David Boulware, MD MPH
🎙️ Just published a new #Communicable episode: Communi...
Hosted by Angela Huttner @angelahuttner.bsky.social
Josh Nosanchuk @josh-nosanchuk.bsky.social
with invited guests:
Hatim Sati (@who.int)
Dimitrios Kontoyiannis (@mdanderson.bsky.social)
Listen here:
#IDSky #Clinmicro #MedSky
Hosted by Angela Huttner @angelahuttner.bsky.social
Josh Nosanchuk @josh-nosanchuk.bsky.social
with invited guests:
Hatim Sati (@who.int)
Dimitrios Kontoyiannis (@mdanderson.bsky.social)
Listen here:
#IDSky #Clinmicro #MedSky
Communicable E34: WHO's Fungal Priority Pathogens List
Fungal infections and disease have long been overlooked in terms of...
share.transistor.fm
August 24, 2025 at 10:00 PM
🎙️ Just published a new #Communicable episode: Communi...
Hosted by Angela Huttner @angelahuttner.bsky.social
Josh Nosanchuk @josh-nosanchuk.bsky.social
with invited guests:
Hatim Sati (@who.int)
Dimitrios Kontoyiannis (@mdanderson.bsky.social)
Listen here:
#IDSky #Clinmicro #MedSky
Hosted by Angela Huttner @angelahuttner.bsky.social
Josh Nosanchuk @josh-nosanchuk.bsky.social
with invited guests:
Hatim Sati (@who.int)
Dimitrios Kontoyiannis (@mdanderson.bsky.social)
Listen here:
#IDSky #Clinmicro #MedSky