Shuangshuang Niu
doubleshuang.bsky.social
Shuangshuang Niu
@doubleshuang.bsky.social
Reposted by Shuangshuang Niu
Nature research paper: ZAK activation at the collided ribosome

go.nature.com/4a9cika
ZAK activation at the collided ribosome - Nature
The kinase ZAK is activated at collided ribosomes to mediate the ribotoxic stress response.
go.nature.com
November 25, 2025 at 10:56 AM
Reposted by Shuangshuang Niu
Check out our latest work on how collided ribosomes activate the MAP3K ZAK! 💫

www.nature.com/articles/s41...

A fun collaboration with @beckmannlab.bsky.social @doubleshuang.bsky.social
ZAK activation at the collided ribosome - Nature
The kinase ZAK is activated at collided ribosomes to mediate the ribotoxic stress response.
www.nature.com
November 24, 2025 at 9:12 PM
Thrilled that our ZAK structures are finally out! It’s been a long but rewarding project. Big thanks to everyone who made this happen - especially to @Vienna Huso for her wonderful biochemistry experiments. It was great teamwork!
How does the kinase ZAK sense ribosome collisions? Find out in our latest collaboration with the @greenlab.bsky.social @doubleshuang.bsky.social @Vienna Huso: 1/4
rdcu.be/eRmJl
#ribosome #cryoEM #LMU #JHMI
November 23, 2025 at 4:12 PM