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dev-journal.bsky.social
Development
@dev-journal.bsky.social
6.2K followers 580 following 560 posts
Development is a leading research journal in the field of developmental biology, covering stem cells, regeneration, evo-devo, epigenetics, morphogenesis and more. @biologists.bsky.social
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Development @dev-journal.bsky.social · 3d
Issue 21 is now complete!

The cover features a human cerebral cortex rosette from Nicolas Loyer.

See the associated Research Article by Alwyn Dady, @profkatestorey.bsky.social and colleagues:
doi.org/10.1242/dev....
The cover Issue 21 of Development featuring a sun-like image of a golden neural rosette.
dev-journal.bsky.social
Midline tissue formation in zebrafish development

This Research Highlight showcases the work from Robert Morabito, Benjamin Martin (@blmartin.bsky.social) and colleagues @stonybrooku.bsky.social :

journals.biologists.com/dev/article/...
Figure 6 - Changing the Wnt:sox2 ratio prevents the dorsal midline NMP to notochord transition. (A-B‴) Transplanting wild-type (WT) rhodamine dextran-labeled cells into the midline progenitor region of host embryos shows transplanted cells contributing to both the floor plate and notochord (A-A‴; red boxes in A and A″ show regions in A′ and A‴, respectively; n=7; all show donor contribution to both notochord and floor plate). When the sox2 level is elevated in transplanted cells, using the HS:sox2 transgenic line, cells stay in the dorsal midline progenitor zone but fail to generate notochord (B-B‴; red boxes in B and B″ show regions in B′ and B‴, respectively; n=11; 11/11 show contribution of donor cells to the floor plate, 7/11 show complete lack of donor cells in notochord after heat-shock induction, 4/11 show a minor amount of notochord contribution at the very posterior tip of the notochord; see Fig. S7).
November 21, 2025 at 12:40 PM
dev-journal.bsky.social
In preprints: folding from the top – apical forces drive eye cup formation

Adrian Perez-Ramos and Paola Bovolenta discuss the recent preprint by Ramos et al. (2025) “The Optic cup is actively shape programmed by independently patterned apical forces”:

journals.biologists.com/dev/article/...
November 21, 2025 at 12:19 PM
dev-journal.bsky.social
Issue 21 is now complete!

The cover features a human cerebral cortex rosette from Nicolas Loyer.

See the associated Research Article by Alwyn Dady, @profkatestorey.bsky.social and colleagues:
doi.org/10.1242/dev....
The cover Issue 21 of Development featuring a sun-like image of a golden neural rosette.
November 19, 2025 at 5:40 PM
dev-journal.bsky.social
Our Editor-in-Chief, @jamesbriscoe.bsky.social, will be attending the 'Engineering Stem Cells and Stem Cell Niches' conference by @novo-nordisk.bsky.social, which starts this weekend.

Please take the opportunity to speak to James about submitting your next paper to Development.
James Briscoe Editor-in-Chief, Development The Francis Crick Institute, UK "Community journals such as Development play a crucial role. Every issue of Development has papers handled by academic editors who are leaders in the field, so it offers a curate collection of the latest developmental biology research selected by experts." Key topics: cell fate control and differentiation, computational biology and modelling, gene regulation and stem cells, neural development and patterning, tissue engineering and organoids
November 19, 2025 at 10:56 AM
dev-journal.bsky.social
Searching for physical principles of morphogenesis

In this #OpenAccess Spotlight, Nikolas Claussen, Fridtjof Brauns and @streichan.bsky.social highlight the ‘physics of development’, focusing on the interplay between quantitative experiments and mathematical theory

doi.org/10.1242/dev....
A figure illustrating examples of physics-inspired theory in developmental biology. Please read the linked article for more information.
November 19, 2025 at 10:28 AM
Reposted by Development
wythelab.bsky.social
New paper from the lab on a new Gateway compatible toolkit for transgenesis in eukaryotes, led by former technician Will Gillespie.

Open access @dev-journal.bsky.social

journals.biologists.com/dev/article/...
MultiSite Assembly of Gateway Induced Clones (MAGIC): a flexible cloning toolbox for use in vertebrate model systems
Summary: A comprehensive suite of Gateway-compatible plasmids for in vitro and in vivo transgenesis in vertebrate model systems has been developed, together with a relational, modifiable, open-source ...
journals.biologists.com
November 14, 2025 at 5:33 PM
dev-journal.bsky.social
In preprints: cell type-specific gene regulation through the lens of echinoderms

Periklis Paganos and @arnonelab.bsky.social discuss a recent #preprint by Jonas Maurice Brandenburg, David Aaron Garfield and colleagues

doi.org/10.1242/dev....
In preprints: a new preprint curation initative from Development
November 18, 2025 at 3:06 PM
Reposted by Development
dev-journal.bsky.social
Development Reviews Editor, Saanjbati Adhikari will also be attending, along with some of our popular 'Development at a glance' poster articles.

Take a browse through our digital collection of posters here:
Page 1 | Search Results | Development | The Company of Biologists
journals.biologists.com
November 10, 2025 at 5:02 PM
Reposted by Development
dev-journal.bsky.social
Development Editor Peter Rugg-Gunn will be attending the upcoming Westlake x Nature Stem Cell 2025 conference, 'Stem cells across the lifespan Embryogenesis | Aging | Therapy,' which starts next week in Hangzhou, China.

Speak to Peter about your next Development paper.
Peter Rugg-Gunn Editor, Development Babraham Institute, UK "Development publishes important, interesting and high-quality papers, as well as a community-centred approach, preprint-friendly policies and a not-for-proft model, which invests back into community support for early-career scientists, etc." Key topics: Early embryogenesis, stem cells, cell fate control and differentiation, chromatin and epigenetics.
November 10, 2025 at 5:02 PM
Reposted by Development
biologists.bsky.social
Looking to publish your paper #OpenAccess? Check if your institution is signed up to our Read & Publish initiative and you can publish #OA for free: www.biologists.com/library-hub/...
November 13, 2025 at 8:33 AM
dev-journal.bsky.social
Plant development: from sessile to fertile.

As part of the #biologists100 anniversary, Ben Scheres discusses the features of plants that make their developmental strategy ‘special’
journals.biologists.com/dev/article/...
The Company of Biologists 100 logo
November 12, 2025 at 5:35 PM
Reposted by Development
researchmar.bsky.social
Dr. Anna Bigas begins a new chapter in @dev-journal.bsky.social 📰

She just joined as as an #AssociateEditor of the journal, which focuses on developmental #biology and diseases associated with embryonic processes

#TalentMAR @biologists.bsky.social @prbb.org

researchmar.net/noticies/139...
November 11, 2025 at 8:50 AM
dev-journal.bsky.social
We are delighted to welcome Anna Bigas from @researchmar.bsky.social and Josep Carreras Leukemia Research Institute as a new Associate Editor at Development, handling papers on #haematopoiesis, #signalling and #cancer.

journals.biologists.com/dev/pages/ed...
Anna Bigas Associate Editor, Development Hospital de Mar Research Institute (HMRIB) and Josep Carreras Lukaemia Research Institute (IJC), Spain "I look forward to handling appers on developmental haematopoiesis and haematopoietic stem cells. I can also handle Notch signalling papers in different systems, as well as papers on cancer and leukaemia mechanisms." Key topics: development and disease, haematopoiesis, signalling, stem cells.
November 11, 2025 at 10:47 AM
dev-journal.bsky.social
Development Editor Peter Rugg-Gunn will be attending the upcoming Westlake x Nature Stem Cell 2025 conference, 'Stem cells across the lifespan Embryogenesis | Aging | Therapy,' which starts next week in Hangzhou, China.

Speak to Peter about your next Development paper.
Peter Rugg-Gunn Editor, Development Babraham Institute, UK "Development publishes important, interesting and high-quality papers, as well as a community-centred approach, preprint-friendly policies and a not-for-proft model, which invests back into community support for early-career scientists, etc." Key topics: Early embryogenesis, stem cells, cell fate control and differentiation, chromatin and epigenetics.
November 10, 2025 at 5:02 PM
dev-journal.bsky.social
Development's academic and in-house team regularly attends conferences in the fields of #DevBio and #StemCells. Use our conference calendar to see our plans and reach out to us if you want to discuss your research or journal news.

journals.biologists.com/dev/pages/co...
A small screenshot of Development's conference calendar webpage encouraging readers to click the link.
November 10, 2025 at 4:55 PM
Reposted by Development
hannahlong.bsky.social
📣 Paper alert!

I am delighted that our paper exploring the impact of Neanderthal-derived variants on the activity of a disease-associated craniofacial enhancer has been published in Development today!
journals.biologists.com/dev/article/...
November 10, 2025 at 11:11 AM
dev-journal.bsky.social
Neanderthal DNA enhances our understanding of face development

This Research Highlight showcases the work from Hannah Long @hannahlong.bsky.social, Kirsty Uttley @kirstyuttley.bsky.social, Hannah Jüllig @hannahjuellig.bsky.social and colleagues: journals.biologists.com/dev/article/...
November 10, 2025 at 1:04 PM
dev-journal.bsky.social
A new reporter mouse for visualising Hedgehog/GLI signalling activity

This Research Highlight showcases the work from Hannah Schrader Dear, Nicole Franks, Benjamin Allen and colleagues:

journals.biologists.com/dev/article/...
Figure 7 - GLI1, GLI2 and GLI3 dynamically localize to primary cilia in GliFHV MEFs. (A) Diagram showing scheme for immunofluorescence staining of MEFs using ARL13b to mark the primary cilium and γ-tubulin (γTUB) to mark the basal body. (B) qPCR analysis of Gli1 expression in GliFHV MEFs before and after SAG stimulation. (C-D′) FLAG antibody detection in NIH/3T3 cells (C,D) and GliFHV MEFs (C′,D′). (E-F′) HA antibody detection in NIH/3T3 cells (E,F) and GliFHV MEFs (E′,F′). (G-H′) V5 antibody detection in NIH/3T3 cells (G,H) and GliFHV MEFs (G′,H′). Insets in E′-H′ show epitope tag-negative cilia. Scale bar: 5 μm
November 7, 2025 at 12:33 PM
dev-journal.bsky.social
Cortical complexity: cooperation between transcriptional and chromatin regulators

This Research Highlight showcases the work from Sophie Warren, Bader El Farran, José-Manuel Baizabal and colleagues:

journals.biologists.com/dev/article/...
Figure 1 - CtBP1/2 interact with PRDM16 and control neuronal migration; Panel E - IUE of Ctbp1/2 shRNAs at E14.5 followed by the analysis of neuronal migration at P5 indicates a significant increase of GFP+ cells in deep layers and adjacent to the white matter (WM) in comparison to controls. In the rescue condition, Ctbp1/2 shRNAs were co-electroporated with plasmids carrying the shRNA-resistant coding sequences of Ctbp1/2, resulting in a significant decrease of ectopic GFP+ cells in deep layers. Data represent mean+s.d. **P<0.01, ****P<0.001 (unpaired Student's t-test). ns, not significant.
November 6, 2025 at 3:47 PM
Reposted by Development
the-node.bsky.social
Beyond the beginning – development that lasts a lifetime.

An introduction to Development’s latest Special Issue, edited by Merixtell Huch and Mansi Srivastava.

#Editorial ⬇️👀
thenode.biologists.com/beyond-the-b...
Beyond the beginning – development that lasts a lifetime - the Node
Traditionally, developmental biology has been considered the study of the embryo, and significant events such as metamorphosis or birth signify the pinnacle of development. However,
thenode.biologists.com
November 6, 2025 at 2:44 PM
Reposted by Development
jamesbriscoe.bsky.social
Development that lasts a life time. Check out the 2025 special issue of @dev-journal.bsky.social on Lifelong Development: the Maintenance, Regeneration and Plasticity of Tissues

journals.biologists.com/dev/issue/15...
Volume 152 Issue 20 | Development | The Company of Biologists
journals.biologists.com
November 5, 2025 at 8:54 AM
Reposted by Development
biologists.bsky.social
One month left for early-career researchers to apply for a funded place at our Workshop 'Novelty, Co-option and Divergence During Gene Network Evolution' organised by James Hombría & Antónia Monteiro Deadline 5 Dec.
biologists.com/workshops/ju...

@isabelalmudi.bsky.social @jlopezrios.bsky.social
Novelty, Co-option and Divergence During Gene Network Evolution
Novelty, Co-option and Divergence During Gene Network Evolution Recent studies on the evolution of novel traits provide a window of opportunity to understand how existing gene-regulatory networks (GRN...
biologists.com
November 5, 2025 at 7:31 AM
dev-journal.bsky.social
In preprints: multiomics of low temperature acclimation in the era of intensifying temperature fluctuations

One of our 2024 PI fellows Girish Kale (@girishkalephd.bsky.social) discusses the recent #preprint by O’Leary et al., 2025:

doi.org/10.1242/dev....
'In Preprints' poster. In Preprints - A new preprint curation initiative from Development
November 4, 2025 at 3:23 PM
dev-journal.bsky.social
Our Special Issue on Lifelong Development #LifelongDevSI is now complete!

Guest edited by Meri Huch and Mansi Srivastava, it contains 26 research and review-type articles.

On the cover: the dorsal vasculature of an adult zebrafish's first gill arch. See Preußner et al. doi.org/10.1242/dev....
November 3, 2025 at 4:35 PM
dev-journal.bsky.social
Beyond the beginning – development that lasts a lifetime

Read this #LifelongDevSI Editorial by Meritxell Huch (@merihuchlab.bsky.social), Mansi Srivastava and Alex Eve (@amjeve.bsky.social).

doi.org/10.1242/dev....
Beyond the beginning – development that lasts a lifetime
Traditionally, developmental biology has been considered the study of the embryo, and significant events such as metamorphosis or birth signify the pinnacle of development. However, we now better appr...
doi.org
November 3, 2025 at 4:12 PM