Denis Wirtz
@deniswirtz.bsky.social
VP for Research, T.H. Smoot Professor
Depts Chemical and Biomolecular Engn, Pathology, Oncology, INBT
Johns Hopkins University
3D multi-omic, CAR T therapy, cell migration and mechanics
Lab: https://wirtzlab.johnshopkins.edu
Depts Chemical and Biomolecular Engn, Pathology, Oncology, INBT
Johns Hopkins University
3D multi-omic, CAR T therapy, cell migration and mechanics
Lab: https://wirtzlab.johnshopkins.edu
Still my favorite 3D reconstruction of a pancreatic tissue.
Using the CODA workflow, we mapped a billion individual cells in 3D.
Red: pre-cancer lesions
Navy blue: ducts
Light blue: islets of Langerhans
Purple: acini
Green: blood vessels
Yellow: fat
More here: www.nature.com/articles/s41...
Using the CODA workflow, we mapped a billion individual cells in 3D.
Red: pre-cancer lesions
Navy blue: ducts
Light blue: islets of Langerhans
Purple: acini
Green: blood vessels
Yellow: fat
More here: www.nature.com/articles/s41...
November 20, 2025 at 6:34 PM
Still my favorite 3D reconstruction of a pancreatic tissue.
Using the CODA workflow, we mapped a billion individual cells in 3D.
Red: pre-cancer lesions
Navy blue: ducts
Light blue: islets of Langerhans
Purple: acini
Green: blood vessels
Yellow: fat
More here: www.nature.com/articles/s41...
Using the CODA workflow, we mapped a billion individual cells in 3D.
Red: pre-cancer lesions
Navy blue: ducts
Light blue: islets of Langerhans
Purple: acini
Green: blood vessels
Yellow: fat
More here: www.nature.com/articles/s41...
Color-coded CODA maps of fallopian tubes from premenopausal (left) and postmenopausal women.
Magenta: secretory epithelial cells,
Green: ciliated epithelial cells.
More here: www.biorxiv.org/content/10.1...
Magenta: secretory epithelial cells,
Green: ciliated epithelial cells.
More here: www.biorxiv.org/content/10.1...
November 16, 2025 at 3:46 PM
Color-coded CODA maps of fallopian tubes from premenopausal (left) and postmenopausal women.
Magenta: secretory epithelial cells,
Green: ciliated epithelial cells.
More here: www.biorxiv.org/content/10.1...
Magenta: secretory epithelial cells,
Green: ciliated epithelial cells.
More here: www.biorxiv.org/content/10.1...