@delladavid-lab.bsky.social
Researcher fascinated by protein aggregation and its regulation.
#Proteostasis
@BabrahamInst
https://www.babraham.ac.uk/our-research/signalling/della-david
#Proteostasis
@BabrahamInst
https://www.babraham.ac.uk/our-research/signalling/della-david
Pinned
tinyurl.com
🔬We have a fully funded Cambridge Biosciences DTP PhD postion to study #Proteostasis and #Aging in colloboration with @jrkumita.bsky.social @Pharmacology. Details on the project ▶️https://tinyurl.com/2zhkjjhs + bbsrcdtp.lifesci.cam.ac.uk/how-apply . Please RT.
Reposted
Researchers in Leeds have joined experts from across the world in warning that Earth is reaching the first of many climate tipping points that will cause catastrophic harm without urgent action.
#climatecrisis #tippingpoint #auspol www.leeds.ac.uk/news/article...
#climatecrisis #tippingpoint #auspol www.leeds.ac.uk/news/article...
‘New reality’ as world reaches first climate tipping point
Researchers in Leeds have joined experts from across the world in warning that Earth is reaching the first of many climate tipping points that will cause catastrophic harm without urgent action.
www.leeds.ac.uk
October 13, 2025 at 10:38 AM
Researchers in Leeds have joined experts from across the world in warning that Earth is reaching the first of many climate tipping points that will cause catastrophic harm without urgent action.
#climatecrisis #tippingpoint #auspol www.leeds.ac.uk/news/article...
#climatecrisis #tippingpoint #auspol www.leeds.ac.uk/news/article...
Reposted
Nominate an outstanding mid-career scientist for the prestigious GSA Medal today. This award honors impactful contributions to genetics and dedication to advancing the community. Nominations close October 1!
🔗 buff.ly/YwPhnVq
🔗 buff.ly/YwPhnVq
September 29, 2025 at 4:04 PM
Nominate an outstanding mid-career scientist for the prestigious GSA Medal today. This award honors impactful contributions to genetics and dedication to advancing the community. Nominations close October 1!
🔗 buff.ly/YwPhnVq
🔗 buff.ly/YwPhnVq
Reposted
Please help spread the word about our inaugural public lecture on Wednesday. Sign up and if you are in the ageing field it’s a great opp for your family to finally understand what you do! 😀
Thanks for your support 🙏
bsra.org.uk/events/bsra-...
Thanks for your support 🙏
bsra.org.uk/events/bsra-...
BSRA Online Public Seminar Series - BSRA
In our new Understanding Ageing: Meet the Scientists series, we’ve invited experts in their field to talk about their research and what it means for each of us as we get older. You don’t need any scie...
bsra.org.uk
September 29, 2025 at 5:39 PM
Please help spread the word about our inaugural public lecture on Wednesday. Sign up and if you are in the ageing field it’s a great opp for your family to finally understand what you do! 😀
Thanks for your support 🙏
bsra.org.uk/events/bsra-...
Thanks for your support 🙏
bsra.org.uk/events/bsra-...
Reposted
Learn all things C. elegans #research at the EMBO | The Company of Biologists Workshop "C. elegans Biology: IV LAWM" in Merida, Mexico, 24–28 February 2026.
Registration by 16 January 2026
Abstract submission by 17 October 2025
meetings.embo.org/event/26-worm
#EMBOWorms2026 #EMBOevents 🧪
Registration by 16 January 2026
Abstract submission by 17 October 2025
meetings.embo.org/event/26-worm
#EMBOWorms2026 #EMBOevents 🧪
C. elegans Biology: IV LAWM
This EMBO Workshop on C. elegans Biology is t he IV Latin American Worm Meeting. It will convene in Mérida, Mexico. The overall mission of this meeting is to create an inclusive environment that pro…
meetings.embo.org
September 23, 2025 at 1:17 PM
Learn all things C. elegans #research at the EMBO | The Company of Biologists Workshop "C. elegans Biology: IV LAWM" in Merida, Mexico, 24–28 February 2026.
Registration by 16 January 2026
Abstract submission by 17 October 2025
meetings.embo.org/event/26-worm
#EMBOWorms2026 #EMBOevents 🧪
Registration by 16 January 2026
Abstract submission by 17 October 2025
meetings.embo.org/event/26-worm
#EMBOWorms2026 #EMBOevents 🧪
🔬We have a fully funded Cambridge Biosciences DTP PhD postion to study #Proteostasis and #Aging in colloboration with @jrkumita.bsky.social @Pharmacology. Details on the project ▶️https://tinyurl.com/2zhkjjhs + bbsrcdtp.lifesci.cam.ac.uk/how-apply . Please RT.
tinyurl.com
September 19, 2025 at 10:53 AM
🔬We have a fully funded Cambridge Biosciences DTP PhD postion to study #Proteostasis and #Aging in colloboration with @jrkumita.bsky.social @Pharmacology. Details on the project ▶️https://tinyurl.com/2zhkjjhs + bbsrcdtp.lifesci.cam.ac.uk/how-apply . Please RT.
Reposted
Exciting news📣: #ProteostasisUK is hiring a network manager to help drive an ambitious, #BBSRC funded initiative connecting and expanding #Proteostasis research across the UK. Position initially for 3 years. Deadline September 28th. More info: tinyurl.com/f83rp673 & proteostasisuk.co.uk Please RT
hireful.
tinyurl.com
September 2, 2025 at 3:04 PM
Exciting news📣: #ProteostasisUK is hiring a network manager to help drive an ambitious, #BBSRC funded initiative connecting and expanding #Proteostasis research across the UK. Position initially for 3 years. Deadline September 28th. More info: tinyurl.com/f83rp673 & proteostasisuk.co.uk Please RT
Reposted
The Vienna BioCenter PhD program in Molecular BioSciences will offer 20+ fully-funded positions in the Autumn Call which is now open. Please share. Further details: www.vbcphd.at
September 5, 2025 at 12:18 PM
The Vienna BioCenter PhD program in Molecular BioSciences will offer 20+ fully-funded positions in the Autumn Call which is now open. Please share. Further details: www.vbcphd.at
Reposted
Exciting FULL PROFESSORSHIP at the Vienna BioCenter - Molecular Mechanisms of Disease Mechanisms: www.maxperutzlabs.ac.at/news/open-po... Come be our colleague!
Full Professorship in Molecular Mechanisms of Disease
The Max Perutz Labs - one of Europe’s leading institutes for basic research in the life sciences - invite applications for a Full Professorship in Molecular Mechanisms of Disease. We are seeking outst...
www.maxperutzlabs.ac.at
September 4, 2025 at 10:25 AM
Exciting FULL PROFESSORSHIP at the Vienna BioCenter - Molecular Mechanisms of Disease Mechanisms: www.maxperutzlabs.ac.at/news/open-po... Come be our colleague!
Beautiful work revealing functional chaperone condensates in the ER.
Happy to share my first publication, where we present our discovery of multi-chaperone condensates that orchestrate protein folding in the endoplasmic reticulum!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
September 2, 2025 at 5:14 PM
Beautiful work revealing functional chaperone condensates in the ER.
Reposted
💫NEW: Mauthe et al. find that protein aggregate clearance requires fragmentation of the aggregate by a chaperone module and a proteasomal regulatory particle for recruitment and clustering of selective #autophagy receptors to initiate phagophore formation.
bit.ly/3JJeJPp
bit.ly/3JJeJPp
A chaperone-proteasome-based fragmentation machinery is essential for aggrephagy - Nature Cell Biology
Mauthe et al. find that protein aggregate clearance requires fragmentation of the aggregate by a chaperone module and a proteasomal regulatory particle for recruitment and clustering of selective auto...
bit.ly
September 2, 2025 at 3:28 PM
💫NEW: Mauthe et al. find that protein aggregate clearance requires fragmentation of the aggregate by a chaperone module and a proteasomal regulatory particle for recruitment and clustering of selective #autophagy receptors to initiate phagophore formation.
bit.ly/3JJeJPp
bit.ly/3JJeJPp
Reposted
Will you be at the @bsrageing.bsky.social #BSRA2025 this week? Look out for Institute contributions:
- @martint-babraham.bsky.social: RNA binding proteins in Tregs (Friday)
- Rahul Samant: proteostasis strategies, stress resilience & senescence (Friday)
- Institute facilities showcase
- @martint-babraham.bsky.social: RNA binding proteins in Tregs (Friday)
- Rahul Samant: proteostasis strategies, stress resilience & senescence (Friday)
- Institute facilities showcase
September 2, 2025 at 10:50 AM
Will you be at the @bsrageing.bsky.social #BSRA2025 this week? Look out for Institute contributions:
- @martint-babraham.bsky.social: RNA binding proteins in Tregs (Friday)
- Rahul Samant: proteostasis strategies, stress resilience & senescence (Friday)
- Institute facilities showcase
- @martint-babraham.bsky.social: RNA binding proteins in Tregs (Friday)
- Rahul Samant: proteostasis strategies, stress resilience & senescence (Friday)
- Institute facilities showcase
Exciting news📣: #ProteostasisUK is hiring a network manager to help drive an ambitious, #BBSRC funded initiative connecting and expanding #Proteostasis research across the UK. Position initially for 3 years. Deadline September 28th. More info: tinyurl.com/f83rp673 & proteostasisuk.co.uk Please RT
hireful.
tinyurl.com
September 2, 2025 at 3:04 PM
Exciting news📣: #ProteostasisUK is hiring a network manager to help drive an ambitious, #BBSRC funded initiative connecting and expanding #Proteostasis research across the UK. Position initially for 3 years. Deadline September 28th. More info: tinyurl.com/f83rp673 & proteostasisuk.co.uk Please RT
Reposted
VACANCY - We’re recruiting for a visionary group leader to lead fundamental research on Discovery Plant Science as part of our vibrant research community
Successful candidate will be offered a six-year tenure-track position with the opportunity to apply for tenure:
www.jic.ac.uk/vacancies/gr...
Successful candidate will be offered a six-year tenure-track position with the opportunity to apply for tenure:
www.jic.ac.uk/vacancies/gr...
August 9, 2025 at 5:15 PM
VACANCY - We’re recruiting for a visionary group leader to lead fundamental research on Discovery Plant Science as part of our vibrant research community
Successful candidate will be offered a six-year tenure-track position with the opportunity to apply for tenure:
www.jic.ac.uk/vacancies/gr...
Successful candidate will be offered a six-year tenure-track position with the opportunity to apply for tenure:
www.jic.ac.uk/vacancies/gr...
Reposted
🚨 Deadline for nominations extended! 🚨
You have one week to nominate someone doing exceptional neuroscience work! 🧠
Whether they’re in the lab, behind the scenes, or amplifying science through communication—nominate them now before the window closes 👩🔬 👨🔬
You have one week to nominate someone doing exceptional neuroscience work! 🧠
Whether they’re in the lab, behind the scenes, or amplifying science through communication—nominate them now before the window closes 👩🔬 👨🔬
August 9, 2025 at 7:32 PM
🚨 Deadline for nominations extended! 🚨
You have one week to nominate someone doing exceptional neuroscience work! 🧠
Whether they’re in the lab, behind the scenes, or amplifying science through communication—nominate them now before the window closes 👩🔬 👨🔬
You have one week to nominate someone doing exceptional neuroscience work! 🧠
Whether they’re in the lab, behind the scenes, or amplifying science through communication—nominate them now before the window closes 👩🔬 👨🔬
Reposted
Exciting news for @ukproteostasis.bsky.social and for #proteostasis researchers across the UK! Funding from BBSRC will support the development of the UK Proteostasis network, including:
- connecting & building the community to accelerate research
- supporting ECRs
www.babraham.ac.uk/news/2025/07...
- connecting & building the community to accelerate research
- supporting ECRs
www.babraham.ac.uk/news/2025/07...
July 31, 2025 at 9:23 AM
Exciting news for @ukproteostasis.bsky.social and for #proteostasis researchers across the UK! Funding from BBSRC will support the development of the UK Proteostasis network, including:
- connecting & building the community to accelerate research
- supporting ECRs
www.babraham.ac.uk/news/2025/07...
- connecting & building the community to accelerate research
- supporting ECRs
www.babraham.ac.uk/news/2025/07...
Reposted
📣Exciting opportunity at @maxperutzlabs.bsky.social 👇
A great chance to join an outstanding research environment, based at campus @viennabiocenter.bsky.social Spread the word or apply!
🆕 #professorship #Professur
🔗 www.maxperutzlabs.ac.at/fileadmin/us...
A great chance to join an outstanding research environment, based at campus @viennabiocenter.bsky.social Spread the word or apply!
🆕 #professorship #Professur
🔗 www.maxperutzlabs.ac.at/fileadmin/us...
📢 Open Call! The Max Perutz Labs invite applications for a Full Professorship in Molecular Mechanisms of Disease. More information ➡️ tinyurl.com/3yn883b8
July 8, 2025 at 2:40 PM
📣Exciting opportunity at @maxperutzlabs.bsky.social 👇
A great chance to join an outstanding research environment, based at campus @viennabiocenter.bsky.social Spread the word or apply!
🆕 #professorship #Professur
🔗 www.maxperutzlabs.ac.at/fileadmin/us...
A great chance to join an outstanding research environment, based at campus @viennabiocenter.bsky.social Spread the word or apply!
🆕 #professorship #Professur
🔗 www.maxperutzlabs.ac.at/fileadmin/us...
Reposted
Exciting Research Professorship Position in Stem Cell and Developmental Biology at the University of Leuven. Amazing research ecosystem, great colleagues, high quality of life, tenure track. For those interested in joining us, please see below:
www.kuleuven.be/personeel/jo...
www.kuleuven.be/personeel/jo...
July 7, 2025 at 2:47 PM
Reposted
We are excited to announce the 11th International Symposium on Autophagy! Deadline for abstraction submission is July 18th, 2025. For more information and registration, please follow this link: www.isa11.org
Speaker opportunities are available for early career researchers and PhD students!
Speaker opportunities are available for early career researchers and PhD students!
July 7, 2025 at 11:33 AM
We are excited to announce the 11th International Symposium on Autophagy! Deadline for abstraction submission is July 18th, 2025. For more information and registration, please follow this link: www.isa11.org
Speaker opportunities are available for early career researchers and PhD students!
Speaker opportunities are available for early career researchers and PhD students!
Reposted
We're recruiting junior team leaders @mrc-lms.bsky.social This time we're looking for those working in human metabolic disease.
It's a great place to start your lab. Fantastic colleagues, exciting science, world class facilities. Join us!
lms.mrc.ac.uk/work/vacanci...
It's a great place to start your lab. Fantastic colleagues, exciting science, world class facilities. Join us!
lms.mrc.ac.uk/work/vacanci...
Programme Leader Track - MRC Laboratory of Medical Sciences
We are recruiting Programme Leader Track positions focusing on 1) Metabolic Physiology using murine and/or human in vivo models and 2) Immunometabolism.
lms.mrc.ac.uk
July 7, 2025 at 8:14 AM
We're recruiting junior team leaders @mrc-lms.bsky.social This time we're looking for those working in human metabolic disease.
It's a great place to start your lab. Fantastic colleagues, exciting science, world class facilities. Join us!
lms.mrc.ac.uk/work/vacanci...
It's a great place to start your lab. Fantastic colleagues, exciting science, world class facilities. Join us!
lms.mrc.ac.uk/work/vacanci...
Reposted
Look out for a Babraham double billing as you plan your schedule for #SEBconference. @delladavid-lab.bsky.social will join @ukproteostasis.bsky.social members in the proteostasis session on day 1, followed by @drsimoncook.bsky.social in the same slot on day 2.
📢 Awesome news
The #SEBconference 2025 Annual Conference programme is now available to download as a PDF!
Check it out and start planning your trip to Antwerp 🇧🇪
www.sebiology.org/events/seb-annual-conference-antwerp-2025/programme.html
The #SEBconference 2025 Annual Conference programme is now available to download as a PDF!
Check it out and start planning your trip to Antwerp 🇧🇪
www.sebiology.org/events/seb-annual-conference-antwerp-2025/programme.html
SEB Annual Conference Antwerp 2025
A full interactive online programme will be made available in the run up to the conference, and printed copies will be available at the venue.
www.sebiology.org
July 7, 2025 at 8:18 AM
Look out for a Babraham double billing as you plan your schedule for #SEBconference. @delladavid-lab.bsky.social will join @ukproteostasis.bsky.social members in the proteostasis session on day 1, followed by @drsimoncook.bsky.social in the same slot on day 2.
We are hiring a research assistant 👉 tinyurl.com/yxebtjbj to join our lab working on healthy #ageing and protein #aggregation in C. elegans 🪱. Deadline August 4th. 🙏 RT. #proteostasis @babrahaminst.bsky.social
hireful.
tinyurl.com
July 4, 2025 at 9:51 AM
We are hiring a research assistant 👉 tinyurl.com/yxebtjbj to join our lab working on healthy #ageing and protein #aggregation in C. elegans 🪱. Deadline August 4th. 🙏 RT. #proteostasis @babrahaminst.bsky.social
Reposted
This is how to have difficult conversations with vaccine sceptics
July 2, 2025 at 3:07 PM
This is how to have difficult conversations with vaccine sceptics
Reposted
Thrilled to share our new study:
“A lysosomal surveillance response to stress extends healthspan”
Knockdown of vha-6 in C. elegans activates LySR—a protective program that boosts lysosomal activity, clears aggregates, and extends lifespan.
www.nature.com/articles/s41...
#lysosomes #LySR #aging
“A lysosomal surveillance response to stress extends healthspan”
Knockdown of vha-6 in C. elegans activates LySR—a protective program that boosts lysosomal activity, clears aggregates, and extends lifespan.
www.nature.com/articles/s41...
#lysosomes #LySR #aging
A lysosomal surveillance response to stress extends healthspan - Nature Cell Biology
Li et al. uncover a lysosomal surveillance response whereby intestinal lumen deacidification induces a transcriptional programme that boosts lysosomal activity and improves protein aggregate clearance...
www.nature.com
June 26, 2025 at 11:02 AM
Thrilled to share our new study:
“A lysosomal surveillance response to stress extends healthspan”
Knockdown of vha-6 in C. elegans activates LySR—a protective program that boosts lysosomal activity, clears aggregates, and extends lifespan.
www.nature.com/articles/s41...
#lysosomes #LySR #aging
“A lysosomal surveillance response to stress extends healthspan”
Knockdown of vha-6 in C. elegans activates LySR—a protective program that boosts lysosomal activity, clears aggregates, and extends lifespan.
www.nature.com/articles/s41...
#lysosomes #LySR #aging
Reposted
It is finally out! My first Science paper is online and it does not seem real😃. I am Incredibly happy! Really thanks to all my coauthors and special mention to my incredible supervisor Ivan Dikic for all the support and trust ! 🫶. #RNA #Proteostasis #ubiquitin #autophagy #RP
doi.org/10.1126/scie...
doi.org/10.1126/scie...
Pathogenic proteotoxicity of cryptic splicing is alleviated by ubiquitination and ER-phagy
RNA splicing enables the functional adaptation of cells to changing contexts. Impaired splicing has been associated with diseases, including retinitis pigmentosa, but the underlying molecular mechanis...
doi.org
November 15, 2024 at 7:14 PM
It is finally out! My first Science paper is online and it does not seem real😃. I am Incredibly happy! Really thanks to all my coauthors and special mention to my incredible supervisor Ivan Dikic for all the support and trust ! 🫶. #RNA #Proteostasis #ubiquitin #autophagy #RP
doi.org/10.1126/scie...
doi.org/10.1126/scie...
Reposted
#NCB2024
In June, Schuh & co analyzed #proteostasis in mammalian #oocytes and ovaries: found that the maintenance of oocytes involves exceptional protein #longevity, and many of the extremely long-lived proteins decline as the ovary ages.
www.nature.com/articles/s41...
In June, Schuh & co analyzed #proteostasis in mammalian #oocytes and ovaries: found that the maintenance of oocytes involves exceptional protein #longevity, and many of the extremely long-lived proteins decline as the ovary ages.
www.nature.com/articles/s41...
The maintenance of oocytes in the mammalian ovary involves extreme protein longevity - Nature Cell Biology
Harasimov, Gorry, Welp, Penir, Horokhovskyi et al. analyse proteostasis in mammalian oocytes and ovaries: the maintenance of oocytes involves exceptional protein longevity, and many of the extremely l...
www.nature.com
December 19, 2024 at 2:13 PM
#NCB2024
In June, Schuh & co analyzed #proteostasis in mammalian #oocytes and ovaries: found that the maintenance of oocytes involves exceptional protein #longevity, and many of the extremely long-lived proteins decline as the ovary ages.
www.nature.com/articles/s41...
In June, Schuh & co analyzed #proteostasis in mammalian #oocytes and ovaries: found that the maintenance of oocytes involves exceptional protein #longevity, and many of the extremely long-lived proteins decline as the ovary ages.
www.nature.com/articles/s41...