Dan Jeffries
@danjeffries.bsky.social
Postdoc/bioinformatician/cyclist - genomics and evolution of reproductive systems 🪴🐸🦎🐟🐞. Co-leader of the Tree of Sex consortium (v2.0) @treeofsex.bsky.social Join us here -> treeofsex.sanger.ac.uk 👍
Have you done any Kmer spectra analyses on the short read data Dan? That might give some clues as to what’s going on.
August 27, 2025 at 7:44 PM
Have you done any Kmer spectra analyses on the short read data Dan? That might give some clues as to what’s going on.
November 11, 2024 at 7:22 AM
Would love to be added. Thanks for putting it together 👍
November 10, 2024 at 6:47 PM
Would love to be added. Thanks for putting it together 👍
Yeh good point. TEs not slowing on Ys might be due to the lower gene density. Most will probably insert into other repeats. So reduced selection against new TEs in degenerated Ys could explain why there’s no slow down(?). No idea why they don’t colonise mt though, maybe mechanistic explanation?
October 23, 2023 at 7:15 PM
Yeh good point. TEs not slowing on Ys might be due to the lower gene density. Most will probably insert into other repeats. So reduced selection against new TEs in degenerated Ys could explain why there’s no slow down(?). No idea why they don’t colonise mt though, maybe mechanistic explanation?
+1 for this answer! Y’s lose dosage insensitive genes rapidly after recomb loss. Degeneration slows a lot as the gene content reduces to those genes which can’t be lost. So all about strength of purifying selection for me
October 23, 2023 at 6:59 PM
+1 for this answer! Y’s lose dosage insensitive genes rapidly after recomb loss. Degeneration slows a lot as the gene content reduces to those genes which can’t be lost. So all about strength of purifying selection for me