Dame lab at Leiden University
@damelab.bsky.social
Interested in the organisation of chromatin in bacteria and archaea, its interplay with transcription and evolution. Methods: single-molecule and ensemble biochemistry, genetics, molecular microbiology, 3D genomics, (computational) structural biology.
Thanks a lot, Harsh!
November 6, 2025 at 9:03 AM
Thanks a lot, Harsh!
DNA bridging has also been established as a DNA binding mode shared by many architectural proteins across the domains of life, with DNA bridging histone proteins in archaea as latest highlight.
September 15, 2025 at 8:21 AM
DNA bridging has also been established as a DNA binding mode shared by many architectural proteins across the domains of life, with DNA bridging histone proteins in archaea as latest highlight.
Research in many different labs has revealed that DNA bridging is key to many of its functions in vivo. 2.5 decades later novel functions of H-NS and mechanisms of functional modulation are still being discovered.
September 15, 2025 at 8:21 AM
Research in many different labs has revealed that DNA bridging is key to many of its functions in vivo. 2.5 decades later novel functions of H-NS and mechanisms of functional modulation are still being discovered.
Great to see it published, Daniela!
July 23, 2025 at 11:30 AM
Great to see it published, Daniela!
So very nice to see the pre-print online - it’s a beautiful story! We’re happy to have been involved.
May 26, 2025 at 8:31 PM
So very nice to see the pre-print online - it’s a beautiful story! We’re happy to have been involved.
It’s great to see this online. We are very glad to have been able to contribute to this work on yet an other very interesting type of bacterial histone.
May 12, 2025 at 3:32 PM
It’s great to see this online. We are very glad to have been able to contribute to this work on yet an other very interesting type of bacterial histone.