dalvalab.bsky.social
@dalvalab.bsky.social
Excited to see our paper out at Science today! Congratulations to all of the authors! Great job, everyone! Thank you!! @dalvalab @science.org
www.science.org/doi/10.1126/...
The synaptic ectokinase VLK triggers the EphB2–NMDAR interaction to drive injury-induced pain
Phosphorylation of hundreds of protein extracellular domains is mediated by two kinase families but the functional role of these kinases is underexplored. We find that the presynaptic release of the t...
www.science.org
November 20, 2025 at 7:37 PM
Want to know more about what those nanoscale puncta of synaptic proteins at synapses might do? The latest work from our lab - a project led by Haani Jafri - addresses this question.
www.biorxiv.org/content/10.1...
Nano-organization of synapses defines synaptic release properties at cortical neuron dendritic spines
Visualization of the submicron organization of excitatory synapses has revealed an unexpectedly ordered architecture consisting of nanocolumns of synaptic proteins that group into nanomodules which sc...
www.biorxiv.org
February 25, 2025 at 9:48 PM
I am excited to use my first post here to highlight new work from the lab on Biorxiv - A new area for us - EphBs and how they regulate migration and cell fate in the RMS - Please let me know what you think! www.biorxiv.org/content/10.1...
Specific neuroblast-derived signals control both cell migration and fate in the rostral migratory stream
Functional neuronal circuits require neuroblasts migrate to appropriate locations and then differentiate into neuronal subtypes. However, it remains unknown how neuroblasts in the subventricular zone ...
www.biorxiv.org
February 25, 2025 at 9:46 PM