@covolab.bsky.social
Reposted
Very happy to share our new paper on how machine learning predicts gene family expansions which contribute to oxidative stress resistance across diverse yeast species:
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Machine learning reveals genes impacting oxidative stress resistance across yeasts - Nature Communications
Yeasts are exposed to oxidative stress during routine metabolism, bioproduction, and interactions with other organisms. Here, the authors use a machine learning classifier to identify genes that are p...
www.nature.com
July 1, 2025 at 9:04 PM
Very happy to share our new paper on how machine learning predicts gene family expansions which contribute to oxidative stress resistance across diverse yeast species:
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted
It’s out! The evolutionary origins of yeast point centromeres uncovered!
“Ancient co-option of LTR retrotransposons as yeast centromeres”
www.biorxiv.org/content/10.1...
“Ancient co-option of LTR retrotransposons as yeast centromeres”
www.biorxiv.org/content/10.1...
Ancient co-option of LTR retrotransposons as yeast centromeres
The evolutionary origins of the genetic point centromere in the brewer's yeast Saccharomyces cerevisiae, a member of the order Saccharomycetales, are still unknown. Competing hypotheses suggest that t...
www.biorxiv.org
April 25, 2025 at 1:59 PM
It’s out! The evolutionary origins of yeast point centromeres uncovered!
“Ancient co-option of LTR retrotransposons as yeast centromeres”
www.biorxiv.org/content/10.1...
“Ancient co-option of LTR retrotransposons as yeast centromeres”
www.biorxiv.org/content/10.1...
Reposted
Two mycologists profiled here discussing the enormous recent changes in their careers 🍄🟫🍄💔
I am extremely pleased to share this feature articulating why I have lost my sanity lately. www.science.org/content/arti...
U.S. scientists’ lives and careers are being upended. Here are five of their stories
As the second Trump administration sends U.S. science into upheaval, countless researchers are fighting for their futures
www.science.org
May 4, 2025 at 3:39 AM
Two mycologists profiled here discussing the enormous recent changes in their careers 🍄🟫🍄💔
Reposted
Excited to share our latest paper, now online in Molecular Cell. First, it shows that the RNAPII-CTD kinases CDK9 and CDK12 are Ser5-Ser2 kinases. Secondly, it describes the activation mechanism of CDK12/13 by PAF1C complex. Congratulations to David López Martínez and coauthors!
lnkd.in/d_nbfMht
lnkd.in/d_nbfMht
LinkedIn
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lnkd.in
May 3, 2025 at 11:17 AM
Excited to share our latest paper, now online in Molecular Cell. First, it shows that the RNAPII-CTD kinases CDK9 and CDK12 are Ser5-Ser2 kinases. Secondly, it describes the activation mechanism of CDK12/13 by PAF1C complex. Congratulations to David López Martínez and coauthors!
lnkd.in/d_nbfMht
lnkd.in/d_nbfMht
Reposted
In our new paper, we uncover a damaged chromatin marking mechanism that drives the non-random segregation of UV damage through mitosis. Chromatin alterations impinge on genome stability by controlling DNA damage segregation
See Ferrand*, Dabin* et al., Nat Commun 2025.
See Ferrand*, Dabin* et al., Nat Commun 2025.
February 8, 2025 at 3:14 PM
In our new paper, we uncover a damaged chromatin marking mechanism that drives the non-random segregation of UV damage through mitosis. Chromatin alterations impinge on genome stability by controlling DNA damage segregation
See Ferrand*, Dabin* et al., Nat Commun 2025.
See Ferrand*, Dabin* et al., Nat Commun 2025.
Reposted
Janevska @slavi-jan.bsky.social et al engineered an Aspergillus nidulans chassis for psilocybin production by repressing L-tryptophan catabolism. Deleting aminotransferase genes aroH1 and aroH2 led to a 10-fold increase in psilocybin yield. Read ➡️ https://buff.ly/4g8VutI
December 3, 2024 at 11:00 AM
Janevska @slavi-jan.bsky.social et al engineered an Aspergillus nidulans chassis for psilocybin production by repressing L-tryptophan catabolism. Deleting aminotransferase genes aroH1 and aroH2 led to a 10-fold increase in psilocybin yield. Read ➡️ https://buff.ly/4g8VutI
Reposted
This is a wonderful paper by @mfseidl.bsky.social and colleagues doi.org/10.1371/jour...
Pangenome graph analysis reveals extensive effector copy-number variation in spinach downy mildew
Author summary Plant pathogens are known to evolve rapidly and overcome disease resistance of newly introduced crop varieties. This swift adaptation is visible in the genomes of these pathogens, which...
doi.org
November 18, 2024 at 10:46 PM
This is a wonderful paper by @mfseidl.bsky.social and colleagues doi.org/10.1371/jour...