Corinne Croslyn
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corinnecroslyn.bsky.social
Corinne Croslyn
@corinnecroslyn.bsky.social
Ph.D. Candidate in Developmental Biology 🧪| Blythe Lab 🪰| Northwestern University 💜 | I study how epigenetic modifications function in the context of patterning cues 🧬
Reposted by Corinne Croslyn
Thanks to Ellie, Natalie, and @corinnecroslyn.bsky.social for driving these projects and to everyone who helped along the way.

Check out the full preprint here:
doi.org/10.1101/2025...

10/10 (end)
doi.org
July 29, 2025 at 11:44 PM
Reposted by Corinne Croslyn
Happy to announce a new preprint from my lab looking in to the establishment of polycomb domains in early fly development and contributions from pioneer factors Zelda and GAGA-factor.
Nucleation-dependent propagation of Polycomb modifications emerges during the Drosophila maternal to zygotic transition https://www.biorxiv.org/content/10.1101/2025.07.02.662854v1
July 3, 2025 at 9:44 PM
Reposted by Corinne Croslyn
Very proud to share the latest preprint from my lab by Ellie Degen and co. Here Ellie shows that a concentration threshold in the Bcd morphogen gradient is determined by competition with nucleosomes. Great mix of math, imaging, and genomics!
Bicoid-nucleosome competition sets a concentration threshold for transcription constrained by genome replication https://www.biorxiv.org/content/10.1101/2024.12.10.627802v1
December 12, 2024 at 4:22 PM