Andrea Corbetta
@corbettandrea.bsky.social
PhD Student in Human Technopole, Milan
Answers seeker in any data
Answers seeker in any data
Reposted by Andrea Corbetta
🧬💥 Do the genetics that make you develop a disease also help you survive it? Not much.
Our new study in Nature Genetics including 9 disease and 7 biobanks shows:
• Susceptibility variants ≠ survival
• PRSs for onset weak at predicting progression
• Lifespan PRS predicts survival better
Our new study in Nature Genetics including 9 disease and 7 biobanks shows:
• Susceptibility variants ≠ survival
• PRSs for onset weak at predicting progression
• Lifespan PRS predicts survival better
September 30, 2025 at 12:50 PM
🧬💥 Do the genetics that make you develop a disease also help you survive it? Not much.
Our new study in Nature Genetics including 9 disease and 7 biobanks shows:
• Susceptibility variants ≠ survival
• PRSs for onset weak at predicting progression
• Lifespan PRS predicts survival better
Our new study in Nature Genetics including 9 disease and 7 biobanks shows:
• Susceptibility variants ≠ survival
• PRSs for onset weak at predicting progression
• Lifespan PRS predicts survival better
Reposted by Andrea Corbetta
💥 New preprint & our first RCT! 💥
Does an extremely high or low BMI polygenic score influence weight loss after a diet intervention?
GENEROOS is a 6-month randomized diet vs. control trial testing if genetic predisposition to higher BMI affects weight loss in overweight adults
Does an extremely high or low BMI polygenic score influence weight loss after a diet intervention?
GENEROOS is a 6-month randomized diet vs. control trial testing if genetic predisposition to higher BMI affects weight loss in overweight adults
October 8, 2025 at 8:01 PM
💥 New preprint & our first RCT! 💥
Does an extremely high or low BMI polygenic score influence weight loss after a diet intervention?
GENEROOS is a 6-month randomized diet vs. control trial testing if genetic predisposition to higher BMI affects weight loss in overweight adults
Does an extremely high or low BMI polygenic score influence weight loss after a diet intervention?
GENEROOS is a 6-month randomized diet vs. control trial testing if genetic predisposition to higher BMI affects weight loss in overweight adults
Reposted by Andrea Corbetta
🎉 New preprint out!
"Removing genetic effects on plasma proteins enhances their utility as disease biomarkers"
We show that adjusting plasma proteins for genetic effects can make them stronger predictors of disease
👉 doi.org/10.1101/2025...
"Removing genetic effects on plasma proteins enhances their utility as disease biomarkers"
We show that adjusting plasma proteins for genetic effects can make them stronger predictors of disease
👉 doi.org/10.1101/2025...
October 16, 2025 at 9:16 PM
🎉 New preprint out!
"Removing genetic effects on plasma proteins enhances their utility as disease biomarkers"
We show that adjusting plasma proteins for genetic effects can make them stronger predictors of disease
👉 doi.org/10.1101/2025...
"Removing genetic effects on plasma proteins enhances their utility as disease biomarkers"
We show that adjusting plasma proteins for genetic effects can make them stronger predictors of disease
👉 doi.org/10.1101/2025...
Reposted by Andrea Corbetta
May 24, 2025 at 8:42 AM
Reposted by Andrea Corbetta
Finally out!🤩
My first first-author publication is now online. We explored the molecular mechanism underlying the genetic correlation between #BMI and #brain morphology.
@cbuunito.bsky.social
journals.plos.org/plosgenetics...
I want to sincerely thank all the co-authors:
My first first-author publication is now online. We explored the molecular mechanism underlying the genetic correlation between #BMI and #brain morphology.
@cbuunito.bsky.social
journals.plos.org/plosgenetics...
I want to sincerely thank all the co-authors:
Exploring the molecular basis of the genetic correlation between body mass index and brain morphological traits
Author summary Obesity is linked to many chronic diseases and its prevalence worldwide is increasing. Susceptibility to obesity is known to be due, to some degree, to genetic factors, and such genetic...
journals.plos.org
April 11, 2025 at 10:32 AM
Finally out!🤩
My first first-author publication is now online. We explored the molecular mechanism underlying the genetic correlation between #BMI and #brain morphology.
@cbuunito.bsky.social
journals.plos.org/plosgenetics...
I want to sincerely thank all the co-authors:
My first first-author publication is now online. We explored the molecular mechanism underlying the genetic correlation between #BMI and #brain morphology.
@cbuunito.bsky.social
journals.plos.org/plosgenetics...
I want to sincerely thank all the co-authors: